Chinese University Of Hong Kong

This study tests whether giving laxatives before inserting a peritoneal dialysis catheter can reduce the chance of blockages. About 400 adults with kidney failure needing dialysis will be randomly assigned to receive laxatives or not before surgery. The goal is to see if this sim…

This study tests whether a modified Chinese herbal formula (Qing-Zao-Jiu-Fei Decoction) can help people with pneumoconiosis, a lung disease caused by inhaling dust. Eighty adults will receive either the herbal granules or a placebo for 16 weeks. The main goal is to see if the tre…

This pilot study tests whether adding fludrocortisone to usual hydrocortisone treatment helps control septic shock in 32 critically ill adults. Septic shock is a life-threatening condition where the body's response to infection causes dangerously low blood pressure. The main goal…

This study tests a temporary pacing technique to slow the heart rate in people with atrial fibrillation (AF) who cannot take standard medications. The approach uses high-frequency pacing in a heart vein to calm the electrical signals. If successful, it could provide a safer, reve…

This study tests a new procedure that uses electrical pulses to rejuvenate the lining of the first part of the small intestine (duodenum) in people recently diagnosed with type 2 diabetes. The goal is to see if this can help control blood sugar and possibly allow participants to …

This study will test a new robotic surgical system (Sentire Surgical System with a Patient Side Single Arm) in 12 people who need surgery for colorectal cancer or large polyps. The goal is to see if this lower-cost system works as well as current robotic systems, with fewer compl…

This study tests whether semaglutide, a drug used for diabetes, can slow the buildup of plaque in arteries of people with psoriatic arthritis who do not have diabetes. About 40 participants will receive either semaglutide or standard care for 24 weeks. Researchers will measure ar…

This study tests a 6-week program designed for people with high blood pressure who find health information hard to understand. Participants will attend three in-person and three phone sessions with easy-to-use materials. The goal is to see if this approach helps lower blood press…

This study tests a 3-month coaching program to help people with coronary heart disease reduce their daily sitting time. 232 adults recently diagnosed with heart disease will either receive the coaching (face-to-face and phone sessions) or standard care. The goal is to see if the …

This study compares two surgical methods for a severe tear in the main artery from the heart (acute type A aortic dissection). One method is simpler (hemiarch repair), the other is more complex (total arch replacement with frozen elephant trunk). The goal is to see which approach…

This study will follow 100 adults with von Hippel-Lindau (VHL) disease who choose to take belzutifan. Researchers will track how well the drug shrinks tumors, its side effects, and its effect on quality of life and healthcare costs. The goal is to gather real-world data on this t…

This study tests whether a chatbot can help men who have sex with men in Hong Kong reduce chemsex—using drugs like ketamine or methamphetamine before or during sex. One hundred men will be randomly assigned to either watch weekly educational videos or also interact with a chatbot…

This study tests whether mixing a woman's own platelet-rich plasma (PRP) with her partner's sperm before intrauterine insemination (IUI) can increase the chance of pregnancy. About 288 women with infertility will take part. The goal is to see if this simple addition safely improv…

This study tests whether a daily synbiotic formula (SGR11) can improve symptoms and quality of life in 50 adults with mild to moderate ulcerative colitis, a type of inflammatory bowel disease. Participants take the formula for 8 weeks and complete questionnaires and stool tests. …

This study tests a procedure called ReCET that uses mild electrical pulses to treat the lining of the small intestine. It aims to improve blood sugar control and reduce fat in the liver for people with type 2 diabetes and fatty liver disease who haven't had success with standard …

This study tests whether a respiratory syncytial virus (RSV) vaccine can reduce moderate-to-severe COPD flare-ups in people who have frequent attacks. Researchers will enroll 320 COPD patients who have had at least two flare-ups in the past year despite using standard inhalers. H…

This study compares a new blood test that looks for TB DNA in the blood against the standard method of using a scope to collect lung fluid. Researchers will enroll 600 adults who need a bronchoscopy to check for TB. If the blood test works as well, patients could get a faster, sa…

This study aims to see if a new liquid biopsy test, which measures TB DNA in fluid from around the lungs, can accurately diagnose tuberculous pleuritis (TB in the lining of the lungs). Current tests often miss the infection or require a painful needle biopsy. The researchers will…

This study tests whether adding a special PET scan (18F-PSMA) to an MRI can better detect serious prostate cancer in men whose MRI results are not clear. About 250 men will be randomly assigned to get either an MRI-guided biopsy or a combined MRI+PET-guided biopsy. The goal is to…

This study tests a smartphone app called GoodShleep+ that provides personalized sleep and circadian advice exactly when you need it. Researchers will enroll 80 adults in Hong Kong who have had sleep or circadian problems for at least 3 months. Half will use the app for 8 weeks, w…

This study tests whether myofunctional therapy—special exercises for the tongue, face, and breathing muscles—can improve sleep in children aged 6 to 12 with obstructive sleep apnea. Half of the 174 children will receive the therapy plus standard care, while the other half gets st…

This study looks at whether a 6-week mindfulness program can improve well-being, reduce stress, and boost job performance for hotel employees. About 60 hotel staff in Hong Kong will take part. Researchers will measure changes in emotional labor, burnout, job satisfaction, and str…

This study looks at whether adding a very low dose (4 mg) of the steroid prednisolone to standard rheumatoid arthritis (RA) treatment can improve symptoms in newly diagnosed patients. About 112 adults with active RA will receive either prednisolone or a placebo for 5 weeks, then …

This study tests whether group activities that bring back fond memories can help older adults feel less lonely. About 294 people aged 60 and older living in Hong Kong communities will take part. They will join nostalgia sessions and researchers will measure changes in loneliness,…

This study tests whether a Mediterranean diet, adapted for Chinese tastes, can reduce depression symptoms in 90 Hong Kong adults with moderate to severe depression. Participants will follow the diet and report their mood and diet quality using frequent phone surveys. The study al…

This pilot study will test a 12-week telehealth program for frail adults aged 65 and older who have just left the hospital. Participants will receive weekly coaching sessions and use activity sensors to track their progress. The goal is to see if the program improves physical fit…

This study tests a new, non-invasive brain stimulation method (so-tDCS) in 80 older adults (60-85) who have memory and sleep complaints. Participants will receive either real or sham stimulation for 4 weeks. Researchers will measure changes in memory, sleep quality, and brain hea…

This study explores whether a special blood product called pure platelet-rich plasma (P-PRP) can improve sperm movement. In the first phase, researchers will standardize how to prepare P-PRP. In the second phase, they will mix sperm samples with P-PRP to see if it increases motil…

This study tests whether two natural supplements, butyrate and taurine, can prevent chronic pain after heart surgery. About 216 adults having elective heart surgery will take either the supplements or a placebo daily for three months. The main goal is to see if fewer people devel…

This study tests whether fezolinetant can reduce hot flashes in men with prostate cancer who are on hormone therapy (ADT). About 54 men will be randomly assigned to receive the drug or a placebo. The main goal is to see if the drug lowers the frequency and severity of hot flashes…

This study tests a smartphone app called GoodShleep that gives personalized, in-the-moment tips to help people with sleep and circadian problems. About 77 adults in Hong Kong will wear a sleep tracker and answer quick surveys to see if tailored suggestions work better than generi…

This study aims to see which treatment—lobectomy, segmentectomy, or a newer ablation technique—best preserves lung function in people with early-stage lung cancer. Researchers will use machine learning to combine 3D CT scans and breathing tests to predict recovery over two years.…

This study uses machine learning to predict how well people recover after ACL surgery. Researchers will combine muscle strength and size measurements to identify patients who may not respond well to standard rehab. About 182 participants will be followed for one year after surger…

This pilot study will test whether a thin, flexible camera inserted through the urinary tract can safely monitor people who have had kidney-sparing surgery for upper tract urothelial carcinoma. Ten adults will undergo the procedure under local anesthesia (awake but numb) to see i…

This online study with 2,800 Hong Kong adults tests whether putting warning labels on sugary drinks (like sodas) makes people less likely to buy them. Participants will choose a drink in a simulated shopping task. The goal is to see if these labels can help reduce sugar intake an…

This study follows 160 Hong Kong residents aged 18 to 70 to see if their daily rest-activity rhythms can predict who develops major depressive disorder. Participants wear a device to track sleep and movement and complete questionnaires over time. No treatment is given; the goal i…

This study creates a long-term registry for 200 adults, both with and without Achilles tendon problems. Researchers will track participants over five years using physical tests, ultrasounds, and questionnaires to see which treatments work best and identify injury risk factors. Th…

This early-stage study tests a new robotic system designed to help doctors remove early rectal tumors through the body's natural openings, avoiding any incisions. The robot aims to make a difficult procedure called endoscopic submucosal dissection (ESD) easier and more precise. T…

This study looks at how well ovarian tissue freezing works for young cancer patients (ages 0-18) who may lose fertility due to treatment. Researchers will follow 100 patients in Hong Kong to see pregnancy rates and any surgical complications after the tissue is transplanted back.…

This study looks at how young people (ages 18-45) understand and try to prevent long-term diseases like heart disease and diabetes. Researchers will survey 5,000 Cantonese-speaking adults about their health habits, including smoking, drinking, diet, and exercise. The goal is to f…

This study looks for hidden heart and kidney problems in 150 adults hospitalized for a COPD flare-up. Researchers will screen patients and track their health to understand risks and improve future care. The goal is to learn, not to test a new treatment.

This study will test a new single-port surgical robot called SHURUI for chest surgeries like lung and mediastinal tumor removal. The robot uses flexible tools to operate through one small cut, aiming for less pain and faster recovery. About 40 adults aged 18-75 who need these sur…

This study aims to measure how common RSV infections are in adults with respiratory symptoms in Hong Kong. Researchers will track 10,000 participants to find out how often RSV causes severe illness, such as needing a breathing machine or ICU care. The goal is to fill gaps in know…