Chinese University Of Hong Kong

This study tests whether the sleep medication trazodone can slow down memory decline in people who have both mild cognitive impairment (MCI) and obstructive sleep apnea (OSA). About 134 participants will take either trazodone or a placebo for one year. Researchers will measure ch…

This study tests a health behavior program designed to help adults with both metabolic syndrome and chronic kidney disease reduce their waist size and improve kidney function. 160 participants will be split into two groups: one receives the program, the other standard care. Resea…

This study tests a new surgical technique to close a macular hole (a small gap in the center of the retina) in people with high nearsightedness. Instead of using a gas bubble after surgery, doctors use a gel-like substance to hold the hole closed. The goal is to see if this appro…

This study tests a new way to deliver chemotherapy for stomach cancer that has spread to the lining of the abdomen. Doctors use a spray of two chemotherapy drugs under pressure during a keyhole surgery. The goal is to see if it is safe and helps control the disease. 30 adults age…

This study compares two radiation treatments for low or intermediate risk prostate cancer in Asian patients. One is a newer, shorter course called stereotactic body radiotherapy (SBRT), and the other is standard intensity-modulated radiotherapy (IMRT). The main goal is to see whi…

This study tests a new robotic tool called the EndoR Surgical System for removing abnormal growths in the colon or rectum. The goal is to see if the robot helps doctors remove these growths more safely and completely than standard methods. Six adults aged 18 to 85 with certain co…

This study looks at two different endoscopic procedures to prevent repeat bleeding from enlarged veins in the esophagus in people with liver cancer. About 70 participants who had already bled once were treated with either a glue injection guided by ultrasound or a standard bandin…

This study looks at whether matching when you eat to your natural sleep-wake pattern (chronotype) helps reduce belly fat and improve health. About 90 adults with central obesity who are not very active will try a 12-week eating plan where they eat only during a set window each da…

This study tested a powerful chemotherapy combination (FOLFOXIRI) followed by chemoradiation before surgery in 40 people with high-risk rectal cancer. The goal was to shrink tumors enough to allow complete removal. Researchers measured how well the tumors responded and tracked si…

This study tests a 10-session talking therapy designed to help people with recent-onset psychosis better understand and accept their medication. Researchers will compare medication adherence and attitudes toward treatment between those who receive the therapy plus usual care and …

This study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy and radiation can help people with stage IVA nasopharyngeal cancer live longer without their cancer growing. About 43 adults with previously untreated, EBV-positive cancer will receive t…

This study is testing a new, non-invasive MRI technique that can measure liver fat, fatty acid makeup, and fibrosis (scarring) all in a single breath-hold of less than 14 seconds. It aims to provide a safer alternative to liver biopsy for diagnosing non-alcoholic steatohepatitis …

This study compares an AI system to standard doctor judgment for diagnosing colon polyps during colonoscopy. About 1,764 adults having a routine colonoscopy will take part. The goal is to see if AI can accurately tell which polyps are harmless and which need removal, potentially …

This study tests a new AI system that helps doctors find early stomach cancer during a scope exam. About 260 people at high risk for stomach cancer will have two endoscopies: one without AI and one with AI. The goal is to see if the AI can catch cancers that might otherwise be mi…

This study tests a new digital scope that lets doctors see inside the bile duct more clearly during a standard procedure. The goal is to better tell apart cancerous from non-cancerous narrowings, which is often difficult with current methods. About 40 adults with suspected bile d…

This study tests whether a vaccine designed for meningitis B can also protect against gonorrhea, a common sexually transmitted infection. Researchers will give two doses of the vaccine or a placebo to 150 men who have sex with men and are at high risk for gonorrhea. The goal is t…

This study tests whether a program of diet counseling, exercise coaching, and an online platform can help women who had gestational diabetes prevent type 2 diabetes. 800 women will be followed for 3 years after giving birth. The goal is to see if this support helps keep blood sug…

This study tests whether mailing HIV self-test kits to men who have sex with men on a subscription basis encourages more frequent testing. 240 participants in Hong Kong will be reminded to test via text messages for part of the year, then receive actual test kits in the mail for …

This study tests a program called Building Respectful Online Space (BROS) to prevent cyberbullying in about 120 Hong Kong secondary school students aged 12 to 15. The program was created with input from teens themselves. Researchers will compare the BROS group to a control group …

This study tests a fixed-dose combination of two drugs, netupitant and palonosetron (NEPA), to prevent nausea and vomiting caused by chemotherapy in breast cancer patients. About 55 women in Hong Kong receiving a specific chemo regimen (adriamycin and cyclophosphamide) will take …

This study tests whether an app that teaches healthy sleep habits, plus an AI chatbot, can help young people aged 18 to 25 with insomnia sleep better. About 168 participants will use either the app with the chatbot or the app alone. The goal is to see if the chatbot makes the sle…

This study tests a special cooling cap (Orbis Paxman system) to prevent hair loss in Chinese women with breast cancer undergoing chemotherapy. 25 participants will use the cap during chemo sessions. The goal is to see if it safely reduces hair loss and improves quality of life.

This study tests a program where trained peer support workers help adults who recently had their first episode of psychosis. The program focuses on self-care and recovery skills. Researchers will follow 198 participants for 18 months to see if it improves their recovery and daily…

This study tests whether using a bright light box for six weeks can improve mood and sleep in people with bipolar depression who naturally feel more alert in the evening. About 70 adults aged 18-65 will either receive the light therapy or a placebo light. The goal is to see if th…

This study tests a nurse-led sailing program for school-aged children with autism. 184 children aged 7 to 12 will either take part in a 6-day sailing program or do craft activities. Researchers will measure changes in resilience, quality of life, and mood to see if sailing helps.

This study tests a gentle ultrasound treatment aimed at a deep brain area (the hippocampus) to see if it can improve sleep and memory in older adults with early signs of Alzheimer's. Twenty participants aged 60-85 with mild memory issues and poor sleep will receive either real or…

This study looks at 1,800 adults in Hong Kong hospitals who have pneumonia. Researchers use a simple urine test to find out which types of pneumococcus bacteria are causing the infection. The goal is to learn which bacterial strains are most common, which can help improve vaccine…

This study looks at 207 liver cancer patients to see if liver stiffness can predict how well treatments like chemotherapy, targeted therapy, or surgery work. Researchers will track overall survival and treatment side effects. The goal is to better understand which patients might …

This study looks at whether special school activities can help primary school students feel better mentally, sleep better, and be more active after the COVID-19 pandemic. About 40 to 408 children in grades 3 to 5 will take part. Researchers will compare kids who join the new prog…

This study is creating a large biobank of 48,000 people with diabetes in Hong Kong. Researchers will collect blood samples and health data to find genetic markers that predict serious complications like kidney failure, heart disease, and stroke. The goal is to improve early detec…

This study enrolls 2,000 women who had gestational diabetes to track their health over three years. Researchers will monitor blood sugar, blood pressure, and other risks to learn why some women later develop diabetes. No new treatments are tested—the goal is to gather data to imp…

This study looks at gut bacteria in 120 adults with and without fatty pancreas (defined by MRI). Researchers want to see if certain bacteria patterns are linked to the condition, which could lead to simple, non-invasive tests in the future. Participants provide stool samples and …

This study looks at 1,600 adults in Hong Kong who have been diagnosed with asthma or COPD to find out how many actually have both conditions (called Asthma-COPD Overlap). Researchers will track their health for 3 years to see how they do and whether their treatments match current…

This study follows 31 Chinese adults with a specific genetic mutation (IVS4+919G>A) that causes Fabry disease, a condition that can damage the heart and kidneys over time. Researchers will use advanced heart scans and blood tests to track how the disease progresses, even before s…

This study looks at a new way to measure liver and spleen stiffness using an ultrasound done through the stomach (EUS elastography). The goal is to see if this method can better predict serious liver problems like bleeding or fluid buildup in people with chronic liver disease. Ab…