Chinese University Of Hong Kong

This study is testing a new, year-long treatment plan for people with advanced nasopharyngeal cancer (a type of throat cancer). The plan combines an immunotherapy drug (pembrolizumab) with chemotherapy and radiation. The main goal is to see if this approach is safe and can better…

This small pilot study is testing a new robotic surgical system called EndoR. It is designed to help surgeons remove early-stage, pre-cancerous growths in the colon more precisely and safely. The study will enroll 6 patients to see if the system reduces complications like bleedin…

This study tests whether giving strong chemotherapy followed by radiation and another chemotherapy drug before surgery helps shrink rectal tumors in high-risk patients. The goal is to make surgery more successful by reducing tumor size and improving surgical outcomes. Researchers…

This study is testing whether a gentle, non-invasive ultrasound treatment aimed at a deep brain area can help improve sleep quality and memory in older adults showing very early signs of Alzheimer's disease. Participants will receive either the real ultrasound treatment or a sham…

This study is testing whether matching your daily eating window to your natural body clock (whether you're an 'early bird' or 'night owl') is better for reducing belly fat and improving health than a standard eating schedule. Researchers will compare these two time-restricted eat…

This study looked back at medical records to compare two different procedures for preventing dangerous rebleeding in the esophagus of patients with liver cancer. It involved 70 patients who had already experienced a serious bleeding episode. Researchers compared an ultrasound-gui…

This study compares two ways to deliver radiation for early-stage prostate cancer. It tests a shorter treatment schedule (SBRT) against the standard longer schedule (IMRT) in Asian patients. The main goal is to see which approach better preserves patients' quality of life while c…

This study is testing a lifestyle coaching program designed to help people with both metabolic syndrome and chronic kidney disease. The program focuses on improving diet and physical activity. Researchers want to see if this coaching can reduce waist size and help preserve kidney…

This study is testing a new surgical technique to close a hole in the center of the retina (macula) in people with severe nearsightedness. The new method aims to close the hole without using a gas bubble inside the eye, which could help patients recover more easily. Researchers w…

This study is testing whether a special program led by trained peers (people with similar lived experience) can help adults recovering from their first episode of psychosis. The program focuses on teaching self-management skills and fostering hope to improve long-term recovery an…

This study is testing if a common sleep medication called trazodone can slow down memory loss in people who have both early-stage memory problems (mild cognitive impairment) and obstructive sleep apnea. Researchers believe treating sleep apnea might help protect the brain. Over o…

This study is testing a new type of MRI scan designed to diagnose a serious form of fatty liver disease called NASH. The goal is to see if this quick, 14-second scan can accurately measure liver fat, inflammation, and scarring without needing a painful needle biopsy. Researchers …

This study is testing a new digital camera scope to see if it can better tell the difference between cancerous and non-cancerous narrowings in the bile duct. Doctors will use the camera during a standard diagnostic procedure called an ERCP on about 40 patients. The goal is to see…

This study is testing a new computer system designed to help doctors find early stomach cancer during routine exams. High-risk patients will have two back-to-back endoscopies: one with the AI system turned off, and one with it turned on to see if it spots growths the doctor misse…

This study is testing a new type of internal ultrasound to see if it can better predict dangerous complications in people with chronic liver disease. The procedure measures the stiffness of the liver and spleen through the stomach wall, which may be more accurate than external sc…

This study is testing whether special school-based programs can help improve children's mental well-being, physical activity, and sleep after the COVID-19 pandemic. Researchers are comparing a program of interactive games and activities to regular school routines. The goal is to …

This study is testing whether a vaccine designed to prevent meningitis can also protect against gonorrhea, a common sexually transmitted infection. It involves 150 men in Hong Kong who are at risk for gonorrhea. Half will receive the real vaccine and half will receive a placebo (…

This study is testing a comprehensive lifestyle support program designed to prevent type 2 diabetes in women who had diabetes during pregnancy (gestational diabetes). It will enroll 800 eligible mothers in Hong Kong. The program includes personalized diet plans, exercise sessions…

This study is testing if a subscription service that mails free HIV self-test kits makes men who have sex with men (MSM) more likely to get tested regularly. Over 240 participants in Hong Kong will first get text reminders to get tested, then later receive the mailed test kits. R…

This study is testing a new school program called BROS (Building Respectful Online Space) that was co-designed with teenagers to prevent cyberbullying. About 90 students aged 12-15 in Hong Kong will try the program, which involves short workshops, and be compared to a group learn…

This study is testing how well a single pill containing two drugs (netupitant and palonosetron, together called NEPA) works to prevent nausea and vomiting caused by a specific type of chemotherapy for breast cancer. It involves about 55 female patients in Hong Kong who are receiv…

This study is testing whether adding daily bright light therapy to standard medication helps people with bipolar depression who naturally prefer evenings ('night owls'). Over six weeks, 70 participants will use either a real bright light device or a placebo device for 30 minutes …

This study is testing a scalp cooling device to see if it can safely prevent or reduce hair loss in Chinese women undergoing chemotherapy for breast cancer. It involves 25 participants who will use the cooling cap during their treatment cycles. The main goal is to collect data on…

This study is testing whether adding an artificial intelligence (AI) chatbot to a smartphone-based therapy app makes it more effective at reducing insomnia in young adults. Researchers are comparing the AI-enhanced app to a standard version of the same therapy app. The goal is to…

This study aims to understand the connection between gut bacteria and fatty pancreas disease. Researchers will analyze stool samples from 120 adults, comparing those with and without the condition. The goal is to see if specific patterns of gut bacteria can serve as a non-invasiv…

This study aims to understand how many people in Hong Kong with asthma or COPD actually have both conditions overlapping. Researchers will observe 1,600 patients with these lung diseases, tracking their health, treatments, and outcomes over three years. The goal is to gather real…

This study aims to create a registry of 2000 women in Hong Kong who had gestational diabetes during pregnancy. Participants will receive health information and regular check-ups for three years after giving birth to monitor their risk of developing type 2 diabetes and other metab…

This study aims to understand why some people with diabetes develop serious heart and kidney problems while others do not. Researchers are collecting detailed health information and blood samples from 48,000 people with diabetes in Hong Kong to look for genetic and other biologic…

This study aims to understand if the stiffness of a patient's liver can help predict how well they will do after standard liver cancer treatments. Researchers are observing 207 patients with liver cancer who are scheduled for treatments like TACE, surgery, or drug therapy. The ma…

This study aims to understand which specific types of pneumonia-causing bacteria are most common in hospitalized patients in Hong Kong. Researchers will test 1,800 adults admitted to the hospital with community-acquired pneumonia using a simple urine test kit. The goal is to gath…