New therapy aims to boost medication adherence in early psychosis
NCT ID NCT06192602
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a 10-session program called AIM-AT, which uses acceptance-based techniques to help people with recent-onset psychosis better understand their illness and stick to their medication. The trial involves 126 participants in Hong Kong and tracks their medication adherence and attitudes over 12 months. The goal is to improve long-term disease control by supporting consistent treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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126 people
The number who actually took part.
- Started
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Feb 2023
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * primarily diagnosed with psychosis (termed recent-onset), including brief, first-episode and other psychotic disorders according to the criteria of the DSM-V (American Psychiatric Association, 2013); * had the mental illness ≤5 years (defined as recent-onset psychosis in recent literature) * Hong Kong Chinese residents, aged 18-64 years; * Global Assessment of Functioning scores ≥51, indicating mild to moderate symptoms and difficulties in psychosocial/occupational functioning (American Psychiatric Association, 2013), thus being mentally stable to comprehend AIM\_AT and/or psychoeducation training; * Unsatisfactory medication adherence as indicated by the Adherence Rating Scale of \<2 (Hayward et al.,1995) during screening; and * Able to read/understand Cantonese/Mandarin. Exclusion Criteria: * Participated in/have recently been receiving other psychotherapies; * Having comorbidity of another mental illness (learning disability, cognitive or personality disorder) and/or clinically significant medical disease; and * Having communication and/or visual/hearing difficulty.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Integrated Community Centers for Mental Wellness
Hong Kong, New Territories, Hong Kong
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Other studies related to the condition(s) this trial covers.
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