PSYCHOTIC DISORDERS

This study tests a special program (LAGOM) designed to improve heart health and quality of life for people with psychotic disorders. 644 adults from six clinics in Gothenburg will take part; some get the program, others get usual care. The program includes regular check-ups, body…

This study tests whether using a person's genetic information to choose psychiatric drugs leads to better recovery than standard prescribing. About 2,500 adults with depression, anxiety, or psychotic disorders will be randomly assigned to either genetic-guided treatment or usual …

This study tests a new, faster version of magnetic seizure therapy (MST) for people with psychotic disorders like schizophrenia. The goal is to see if adding MST to standard antipsychotic medication can improve symptoms and thinking. Fifty adults aged 18-55 will receive the treat…

This study tests a program called Resilience Training for college students who have mild psychotic experiences, like unusual thoughts or perceptions. The goal is to see if this training can prevent the development of serious mental illness. Researchers will enroll 192 students ag…

This study tests a brief group therapy called Resilience Training for Teens. It aims to prevent serious mental illness in high school students aged 14-19 who have mild symptoms of depression, anxiety, or unusual feelings. About 70 teens will participate to see if the training hel…

This study tests whether a 24-week supervised exercise program (aerobic, strength, and flexibility) can improve physical fitness, mood, and quality of life in 44 adults with psychosis who are on long-acting injectable medication. Participants are randomly assigned to either the e…

This study tests whether a yoga-based group program can help outpatients with schizophrenia spectrum disorders feel better. About 60 adults will be randomly assigned to yoga plus usual care, strength training plus usual care, or usual care alone. Researchers will measure stress, …

This study tests a virtual reality cognitive remediation program for people with psychotic disorders like schizophrenia. The program aims to improve thinking, social skills, and daily functioning. Researchers will enroll 52 adults aged 18-60 who are clinically stable. The main go…

This study looks at whether cognitive behavioral therapy (CBT) can help veterans with serious mental illness (like schizophrenia or bipolar disorder) who also have chronic low back pain. About 190 veterans will receive CBT and be monitored for changes in pain interference, qualit…

This study tests a brief, two-session therapy for young adults (ages 18-35) who started early psychosis treatment within the past year. The therapy, co-led by a clinician and a peer support worker, aims to improve treatment engagement and recovery, especially for those who had ne…

This study tests whether a smartphone app called Kiso Mind is acceptable and practical for people with schizophrenia or schizoaffective disorder. About 60 participants will either use the app plus their usual care, or just usual care, for 12 weeks. The main goal is to see if peop…

This study looks at whether cognitive remediation (brain exercises with coaching) can improve thinking skills and reduce problem behaviors in people staying in a forensic mental health unit. About 30 adults with conditions like psychosis, ADHD, or substance use will take part. Th…

This study provides a 9-week education program for family members who care for young adults (ages 17-27) with psychosis. The goal is to see if teaching families practical skills reduces their stress and helps the young person stay stable in the community. Researchers will measure…

This study aims to understand why Black Americans often report higher levels of paranoia than White Americans. Researchers will expose 480 Black American participants to stressful scenarios related to race and measure their feelings of paranoia. The goal is to improve how mental …

This study looks at 200 children and teens (ages 7-20) who have had a psychotic episode, such as in schizophrenia. Researchers will use interviews, brain scans, and genetic tests to group participants by their symptoms. The goal is to see if these groups can predict which antipsy…