Exercise prescription for psychosis: new study tests if moving more boosts mind and body
NCT ID NCT07360665
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 24-week supervised exercise program (aerobic, strength, and flexibility) can improve physical fitness, mood, and quality of life in 44 adults with psychosis who are on long-acting injectable medication. Participants are randomly assigned to either the exercise group or usual care. The goal is to see if adding exercise to standard treatment is practical and helpful.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older; * Clinical diagnosis of psychosis; * Currently undergoing treatment with long-acting injectable antipsychotics (LAIs); * Follow-up at the Antipsychotic Clinic of ULSTMAD; * Certificate of autonomy issued by the treating psychiatrist, confirming the participant's capacity to engage in the study procedures; * Ability to provide written informed consent, either personally or through a legal representative; * (Experimental group only) Residence within a reasonable distance from the physical exercise intervention site to allow attendance at supervised sessions. Exclusion Criteria: * Attendance below 85% of the supervised exercise sessions (experimental group); * Failure to complete the four main assessment time points; * Withdrawal or lack of informed consent at any stage of the study; * Not prescribed long-acting injectable antipsychotics (LAIs); * Not affiliated with or followed at the Antipsychotic Clinic of ULSTMAD.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Local Health Unit of Trás-os-Montes and Alto Douro
RECRUITINGVila Real, 5000, Portugal
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