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Your words could reveal your risk: AI analyzes speech to predict psychosis

NCT ID NCT03525054

Knowledge-focused Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether subtle changes in how people speak can predict who will develop schizophrenia. Researchers will record and analyze free speech from 215 young people aged 15-30 who are at ultra-high risk for psychosis. By using computer programs to detect semantic and syntactic patterns, they hope to build a predictive model that flags early warning signs before a full psychotic episode occurs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple speech test that helps identify young people at high risk of developing schizophrenia before full symptoms appear.
What could go wrong
This is an observational study, not a treatment trial. The speech markers may not prove reliable enough for clinical use, and results may not apply outside the French-speaking population studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 215 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2018

Expected to finish

May 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Help-seekers patients are recruited during two years from the early psychosis detection centers in Brest, France (CEVUP), Paris, France (CJAAD) and in Lausanne, Switzerland

Ages

15 to 30 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Major and/or minor from 15 to 30 years old * Who alleged a suicidal gesture or idea or behavior that has repercussions in their emotional, social or professional life * If patients receive neuroleptic treatment that impairs cognitive abilities, a one-week wash-out period will be scheduled prior to assessment. * Affiliated with or beneficiary of a health insurance/social security system * Able and willing to provide written informed consent Exclusion Criteria: * History of psychosis * Risk of self-harm or violence not compatible with outpatient treatment * QI\<70 (WAIS) * Neurological disorder or major health problem * Impossibility to interrupt neuroleptic treatment for one week * Refusal to participate

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Conditions

The condition(s) this trial relates to.

psychiatric disorder psychotic disorder Psychotic Disorders schizophrenia schizotypal personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diagnosis, psychiatric Psychosis Psychotic disorders Schizophrenia and related disorders Schizophrenia prodromal

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH de SAINT ANNE

    RECRUITING

    Paris, 750144, France

  • CHRU de Brest

    RECRUITING

    Brest, 29609, France

  • Meunier Sophie

    NOT_YET_RECRUITING

    Caen, France

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