University Hospital, Brest

This study is testing whether giving botulinum toxin injections early can prevent shoulder deformity in babies with a nerve injury from birth. Researchers will compare the injections to a sham (placebo) procedure in 62 babies aged 10-11 months who are at risk for shoulder problem…

This study is testing if personalized follow-up support from a sports and health professional helps people with chronic heart failure maintain the benefits of their cardiac rehabilitation program. It will compare 90 patients who receive this personalized coaching for a year after…

This study is testing whether adding a minimally invasive 'glue' procedure can prevent recurring brain bleeds in adults with a chronic subdural hematoma. 550 participants will be randomly assigned to receive either standard care (surgery or medication) or standard care plus the n…

This study is testing if a special fluorescent dye, injected during surgery, can help surgeons better see and preserve tiny glands near the thyroid. These glands control calcium levels. The goal is to reduce the risk of permanent low calcium, a common and serious complication tha…

This study is testing a new decision-making tool to help patients and doctors decide how long to continue blood thinners after a first unprovoked blood clot. The goal is to better balance the risk of another clot against the risk of serious bleeding. It involves 2,400 adults who …

This study is testing a new type of medical imaging scan to see if it can better detect and monitor a wide range of chronic inflammatory and scarring diseases. Researchers will give 390 participants a special tracer and use a PET/CT scanner to see where and how intensely it light…

This study aims to find better ways to predict the long-term diagnosis for people experiencing their first psychotic episode. Researchers will analyze participants' speech patterns and blood markers at the start of the study to see if they can forecast whether the psychosis will …

This study is testing a new type of imaging scan called PSMA PET/CT to see if it can more accurately detect whether prostate cancer has spread to nearby lymph nodes. It involves men with intermediate or high-risk prostate cancer who are scheduled for surgery to remove their prost…

This study is testing whether a school-based prevention program called PREVENTURE can reduce risky alcohol and substance use in teenagers. Researchers will enroll 700 French adolescents aged 14-17 who have already tried alcohol. Participants will be randomly assigned to either re…

This study is testing a parenting skills program for families where at least one parent has an alcohol use disorder. The goal is to see if teaching better parenting and communication skills can help protect children from developing future mental health or substance use problems. …

This large Phase 3 trial aims to prevent life-threatening blood clots in people with certain high-risk blood cancers. It will compare newer, more potent blood thinners (apixaban/rivaroxaban) against standard low-dose aspirin in over 1,300 patients. The goal is to see if the newer…

This study tests whether a special nurse-led program can help prevent serious side effects in people starting long-term steroid treatment. It compares patients who receive the nurse's guidance on prevention (like bone health, vaccines, and diet) to those who get usual care. The g…

This study is testing if a drug called naloxegol can prevent severe constipation and pneumonia in adults with brain injuries who are in intensive care. These patients often need strong opioid painkillers, which can paralyze the gut. Researchers want to see if giving naloxegol ear…

This study aims to see if using a special filtered seawater solution helps infants with bronchiolitis get better faster than the standard saline (saltwater) solution. It will involve 458 infants, aged 1 month to under 1 year, who have a mild to moderate first case of bronchioliti…

This study is testing a new mobile healthcare team that travels to homes and care facilities to help manage pain in children and young adults (up to age 25) with autism, intellectual disabilities, or multiple disabilities. The team provides specialized pain assessments and create…

This study is testing whether a skin patch containing capsaicin, the compound that makes chili peppers hot, can reduce chronic nerve pain in teenagers. It will compare the capsaicin patch to a placebo patch in 46 teens aged 12 to 17 who have had pain for over 3 months following s…

This study aims to understand if young people (ages 15-25) who are at high risk for developing psychosis see themselves differently than others. Researchers are using a special double-sided mirror device that slowly blends a person's face with a stranger's face. By comparing how …

This study aims to understand how the CFTR gene is controlled in cells from the epididymis, a part of the male reproductive system. Researchers will collect small tissue samples from 20 men already scheduled for specific surgeries related to infertility, cystic fibrosis, or a con…

This study aims to validate a French version of a questionnaire designed to measure the burden on caregivers of people with COPD. Researchers will ask 224 caregivers to complete the new questionnaire and other standard surveys to see if it accurately captures their stress and qua…

This study aims to understand the biological reasons behind sensitive scalp, a common condition causing itching, burning, or tingling. Researchers will compare small skin samples from 40 women—20 with sensitive scalp and 20 without—to look for differences in genes, proteins, and …

This study aims to find out if specific signs seen on ultrasound scans of the temples and armpits can predict when symptoms of giant cell arteritis will return. Researchers will follow 100 patients with this condition during their regular doctor visits, using standard ultrasound …

This study aims to combine medical information from 14 different European patient groups into one large database. Researchers will analyze this combined data to better understand and predict risks like recurring blood clots, bleeding complications, and death. The goal is to help …

This study aims to understand how often people with atopic dermatitis (eczema) experience 'alloknesia'—where light touches like clothing or air movement trigger intense itching instead of normal sensation. Researchers will survey 160 adult patients with long-term eczema to measur…

This study aims to find markers in the blood that can predict which cancer patients will develop serious side effects from a common type of immunotherapy. Researchers will collect blood samples from 200 patients at a single hospital in France during their regular cancer check-ups…

This study aims to identify biological and genetic factors that may contribute to repeated miscarriages and unexplained fetal deaths. Researchers are recruiting 200 couples who have experienced these pregnancy losses to compare their genetic profiles with couples who haven't. The…

This study aims to understand how specific immune cells called B cells behave in people with serious gum disease (periodontitis). Researchers will collect blood and gum tissue samples from 60 patients before and after their standard gum surgery. The goal is to learn if certain pa…

This study is testing whether a new digital app called 'Deneo Kid' can help coordinate care for children and young people with neuromotor disabilities. About 20 children, their families, and their rehab professionals in France will use the app for 3 months to share information an…

This study aims to understand how often and why dangerous blood clots return in two specific groups: people under 50 and people with cancer. Researchers will follow 3400 participants over several years to track their health and identify risk factors for recurrence. The goal is to…

This study aims to predict how well people recover their quality of life more than four years after having a minor stroke. Researchers will analyze data from 1,000 patients in France, looking at their early stroke characteristics, health questionnaires, and optional MRI scans and…

This study observes how preterm and full-term babies adapt to lights and sounds in their environment. Researchers want to understand if this adaptation ability can help predict which babies might develop neurological issues later. They'll follow the babies for two years to see ho…

This study aims to improve how doctors measure the muscles that move the eye and the optic nerve in medical scans. Researchers will analyze existing eye scans from 190 adults to check how consistent different measurements are. The goal is to gather better anatomical knowledge to …

This study aims to see if training hospital support staff through realistic simulations improves how satisfied patients feel during their hospital stay after discovering a brain tumor. Researchers will compare patient satisfaction surveys from hospitals where staff received this …