New PET scan could end guesswork after head and neck cancer radiation
NCT ID NCT07417605
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study is testing a new type of PET scan to see if it can tell the difference between cancer that is still there and swelling caused by radiation treatment in people with head and neck cancer. About 180 adults who finished radiation therapy will get this special scan 3 months later. The goal is to help doctors know for sure if more treatment is needed or if the area is just healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients treated with radiotherapy for curative purposes for squamous cell carcinoma of the upper aerodigestive tract.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patient ≥ 18 years of age * Presenting with head and neck squamous cell carcinoma * Completed curative treatment with external radiation therapy * Eligible for dynamic LAFOV FDG-PET scan for therapeutic evaluation at 3 months * Having given consent for the end-of-treatment consultation Exclusion Criteria: * Hypersensitivity to 18F-FDG or other excipients contained in the contrast agent * Pregnancy or breastfeeding * History of treated upper gastrointestinal tract cancer * Other histology * Incomplete RTE treatment regimen * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Brest
RECRUITINGBrest, 29200, France
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Centre finistérien de radiothérapie et d'oncologie - Site de l'hôpital La Cavale Blanche
NOT_YET_RECRUITINGBrest, 29200, France
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Centre finistérien de radiothérapie et d'oncologie - site Clinique Pasteur
NOT_YET_RECRUITINGBrest, 29200, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shrink tumors that resist standard care?
- Cutting radiation after surgery: a new hope for head and neck cancer patients?
- Could a Pre-Chemo drug shield bone marrow in head and neck cancer?
- AI model aims to end guesswork in head and neck cancer care
- Smart radiotherapy aims to cut cancer treatment side effects
- Gut health boost may tame immunotherapy side effects in head and neck cancer