University Hospital, Brest

This pilot study tests whether an active smartwatch that gives real-time feedback, combined with regular nurse coaching, can help people who had a minor stroke or TIA walk more each day. Fifty participants will be randomly assigned to either an active smartwatch or a passive one …

This study compares a semi-intensive therapy program (8 hours per week at a center plus online parent training) to the standard intensive program (15 hours per week) for young children with autism. The goal is to see if the remote approach works just as well for improving develop…

This study tests whether virtual reality (VR) can help improve thinking and daily functioning in people aged 70 and older who have depression. Participants will do 12 VR sessions over 6 weeks, doing tasks like sorting groceries or following recipes. The main goal is to see if sen…

This study tests whether a cannabis oil containing a balanced mix of THC and CBD can safely reduce severe chronic itching. About 218 adults with severe itch (score 7 or higher on a 0-10 scale) that hasn't improved with other treatments will take either the cannabis oil or a place…

This study tests if applying cold (cryotherapy) to the wrist before a blood draw from the artery can reduce pain. It involves 258 adults with chronic respiratory diseases who need this test. The goal is to find a simple, drug-free way to make the procedure less painful.

This study tests whether using a lung perfusion PET/CT scan to guide radiation planning can reduce lung injury compared to standard anatomical planning. About 418 adults with lung tumors receiving stereotactic body radiotherapy (SBRT) will be randomly assigned to one of the two p…

Researchers at a French hospital are observing how pain perception and central sensitization change during a 40-day exercise rehabilitation program on a stationary bike. The study includes 40 adults with chronic low back pain from untreated degenerative spine disease. Participant…

This study asks whether a full bladder changes the angle of the uterus in women whose uterus tilts forward. Researchers will have 30 adult women who have never given birth drink 600 mL of water, then take repeated ultrasound pictures as the bladder fills and after emptying. The g…

This study looks at how aerobic exercise influences pain processing in people with chronic jaw pain (TMD). Researchers will compare pain responses among three groups: patients with jaw pain, inactive healthy people, and healthy endurance athletes. The goal is to understand if exe…

This pilot study will use special PET/CT scans to see how the experimental drug sotatercept affects blood vessel remodeling in the lungs and heart of people with pulmonary arterial hypertension (PAH). About 15 adults with PAH will receive sotatercept and have imaging at the start…

This study will test four different water-drinking plans in 20 healthy women to see which one gives the best bladder filling for a pelvic ultrasound. Participants will drink different amounts of water on different days, and researchers will measure bladder volume and comfort. The…

This study looks at how people with skin conditions (like eczema, psoriasis, or skin cancer) manage stress, feel lonely, and bounce back from challenges. Researchers will compare 375 adults with and without skin disease across 15 European countries using questionnaires. The goal …

This study looks at whether using a 3D-printed copy of a patient's brain aneurysm can help doctors plan treatment and avoid problems. About 40 adults with unruptured aneurysms will have their aneurysm printed from scans, then doctors will practice the procedure on the model befor…

This study will follow 400 people recently diagnosed with polymyalgia rheumatica, a condition causing shoulder and hip pain. Researchers will track symptoms, treatments, and outcomes over 5 years to better understand the disease and improve diagnosis. Participants will provide bl…

This study looks at patients who take aspirin and develop a subdural hematoma, a type of brain bleed. Researchers want to see if a blood test that measures platelet function can help doctors know when it's safe to perform surgery. The goal is to compare the time it takes for plat…

This study looks at how the veins in the head and neck change after certain brain or spine surgeries. Researchers want to understand the body's backup drainage pathways, which may help doctors better prepare for surgery, reduce bleeding, and explain post-surgery headaches. About …

This study compares two methods of accessing the brachial artery in the arm for treating blocked leg arteries: a needle poke through the skin (percutaneous) versus a small cut (open). About 246 adults will be randomly assigned to one method. The goal is to see which approach caus…

This study looks at what patients in the intensive care unit (ICU) consider most important during their stay, and compares that with what their family members and healthcare team think. Researchers will enroll 100 adults expected to stay in the ICU for more than 72 hours, along w…

This study follows 34 athletes aged 15 to 40 who are having ACL reconstruction surgery. Researchers will test their balance before surgery and again 3 and 9 months after, using a force platform and vibrations to see how the body re-learns to use sensory information. The goal is t…

This study aims to find out if some women who had severe bleeding after a vaginal delivery have an undiagnosed bleeding disorder. Researchers will test blood samples from 150 women who lost at least 1000 mL of blood during or after birth in the past year. The goal is to better un…