STROKE, ACUTE

This study tests whether a procedure that removes blood clots from the brain can help stroke patients treated up to 72 hours after symptoms start, using only a basic CT scan available at most hospitals. Currently, this treatment is only proven within 6 hours and requires advanced…

This study looks at two approaches for treating adults who have a severe stroke caused by a blocked large artery in the brain. One group goes directly to a special procedure room for clot removal, while the other group is first checked in the emergency room. The goal is to see wh…

This study tests whether taking stroke patients directly to a special imaging and treatment room (called the Angio Suite) speeds up care and improves recovery. About 594 adults with severe stroke symptoms will be randomly assigned to either the new fast-track approach or the usua…

This study tests a weight-loss program delivered via telehealth for people who have had a stroke. About 94 participants with a BMI of 25 or higher will be randomly assigned to either start the program right away or wait 6 months. The goal is to see if the program helps with weigh…

This study tests a new approach called 'One-Stop management' for treating severe strokes. Instead of moving patients between a CT scan room and a treatment room, both the brain scan and the clot-removal procedure happen in the same room. The goal is to save time and improve recov…

This study looks at whether a procedure called endovascular thrombectomy (EVT) can help people who have a stroke but already had a moderate-to-severe disability before the stroke. About 1,060 adults with a large blood vessel blockage in the brain will be randomly assigned to get …

This study looks at whether adding a gentle brain stimulation technique (rTMS) to standard swallowing therapy can lower the chance of pneumonia in people who have trouble swallowing after a stroke. About 70 adults with moderate to severe swallowing issues will take part. The goal…

This study tests whether a newer clot-busting drug (tenecteplase) works better than the standard drug (alteplase) when given before a mechanical procedure to remove a large blood clot from the brain. About 850 adults who have had a severe stroke within the last 4.5 hours will be …

This study aims to find the safest and most effective dose of the clot-busting drug tenecteplase for people having a severe stroke. About 4,000 participants will receive either a standard or lower dose, or no drug at all in certain cases, to see which approach leads to the best r…

This study tests whether a low-cost virtual reality (VR) platform can help people recovering from a first-time stroke improve arm and hand movement. About 40 adults with moderate to severe arm weakness will either receive standard care or add VR therapy sessions while in the hosp…

This study is testing a wearable device called a myoelectric-computer interface (MCI) to help people who have had a stroke improve arm movement. The device works by giving feedback on individual muscle activations to reduce abnormal co-contractions that limit coordination. The st…

This study tests whether mild electrical stimulation of the vagus nerve (through the ear or neck) can improve arm movement, thinking skills, and quality of life when added to standard therapy. About 54 adults who had a stroke 3–6 months ago will receive either ear or neck stimula…

This study follows 5,000 people who had a stroke and received a procedure to remove a blood clot. Researchers want to see how well patients recover 3 months later. The goal is to collect information that is rarely tracked but important for understanding recovery.

This study looks at blood clots removed from people having a stroke to see if their makeup is linked to what caused the stroke, how well treatment works, and how the person recovers. Researchers will also test participants' blood for related markers. The goal is to learn more abo…

This observational study aims to see if a new, standardized physical exam technique can reliably identify joint motion problems in healthy adults and people hospitalized after a stroke or mini-stroke (TIA). Researchers will compare motion patterns between these groups and check i…

This study looks at whether a simple CT scan can be used to decide if stroke patients need a procedure to remove a blood clot, instead of more complex scans. About 1,846 adults who had a stroke within the last 24 hours will take part. The goal is to see if the simple scan leads t…

This study is testing a new type of MRI scanner, called Field-Cycling Imaging (FCI), to see if it can detect brain changes within the first 24 hours of a stroke. About 40 adults who have had a stroke will get both a standard MRI and the new FCI scan. The goal is to find out if FC…

This study tests whether artificial intelligence can help emergency call operators quickly identify serious conditions like heart attack, stroke, or breathing trouble. Researchers will analyze millions of past emergency calls to build and compare AI models. The goal is to reduce …

This study looks at a blood marker called BD-tau, which may show how much brain injury happens after a stroke. Researchers will take blood samples every hour for 48 hours from 100 adults who had a stroke. The goal is to learn when the marker rises and how long it stays high, whic…

This study is tracking 350 stroke patients in the Asia-Pacific region to see how well a procedure called endovascular thrombectomy (clot removal) works outside of clinical trials. Researchers want to understand what helps or hinders recovery in everyday hospital settings. The goa…

This study looks at whether a nurse-led transitional care program helps stroke survivors, their caregivers, and healthcare providers in Tanzania. Researchers will follow 130 stroke survivors and their caregivers for six months to see if the program improves discharge readiness, s…

This study looks at a new way for hospitals to quickly evaluate stroke patients and decide if they need to be transferred to a specialized center. The goal is to reduce the time it takes from arrival at the first hospital to departure for advanced care. Researchers will track how…

This study tests whether fusing 3D scans with live X-ray images helps doctors access blocked arteries faster during emergency stroke clot removal. About 300 adults having a stroke due to a large clot will be included. The goal is to see if this imaging technique improves success …

This study follows 5,000 adults in Hong Kong who either have or are at high risk for brain diseases like stroke and dementia. Researchers will collect medical records, surveys, and phone interviews over many years to identify what factors lead to these conditions. The goal is to …

This study is testing whether brain scans and a technique called transcranial magnetic stimulation can predict how well someone will recover arm movement after a stroke. Researchers will collect data from 657 adults who recently had a stroke and have arm weakness. The goal is to …

This study examines tiny RNA molecules in the blood of 300 adults who had a stroke and received a procedure to remove the clot. Researchers want to see if certain RNA patterns can help predict how well patients recover. The goal is to find new markers that could guide future stro…

This study aims to understand if COVID-19 vaccines have any impact on brain health. Researchers will use MRI scans to look at the brains of 500 healthy adults in Hong Kong, comparing scans taken before and after vaccination. The goal is to provide clear, evidence-based informatio…