STROKE, ACUTE

This study is testing whether gently stimulating a major nerve through the skin can help people recover better after a recent stroke. Researchers will compare two methods—one behind the ear and one on the neck—when used alongside standard physical therapy. The goal is to see if t…

This large study aims to find the safest and most effective dose of the clot-busting drug tenecteplase for people having a stroke. It will enroll 4,000 stroke patients to compare a standard dose against a lower dose, particularly for older patients and those taking blood thinners…

This study is testing whether treating severe strokes in one room instead of two leads to better recovery. Patients with severe stroke symptoms will be randomly assigned to either have their brain scan and clot-removal procedure done in the same room or in separate rooms as is st…

This study is testing if adding a non-invasive brain stimulation technique to standard swallowing therapy can help prevent pneumonia in people who have trouble swallowing after a stroke. It will involve 70 recent stroke patients in Egypt. One group will get the standard therapy p…

This study compares two approaches for treating severe stroke caused by major blood clots. Researchers want to know if taking patients directly to the specialized treatment room upon hospital arrival leads to better recovery than the standard approach of first evaluating them in …

This study is testing whether a weight loss program delivered through telehealth (video calls and online support) can help people who have had a stroke. Researchers will compare the program to a waitlist group to see if it helps participants lose weight and improve health markers…

This study is testing if a new, faster hospital process leads to better recovery for stroke patients. Instead of going for a CT or MRI scan first, patients go straight to the treatment room where a special scanner is used to diagnose and treat them without delay. Researchers will…

This study is testing whether a simple, widely available brain scan (non-contrast CT) can safely identify stroke patients who could benefit from a clot-removing procedure up to 72 hours after symptoms begin. The procedure, called endovascular therapy, is proven to help when done …

This study is testing whether a home-based brain training program, delivered on a tablet, can help reduce thinking and memory problems after a stroke. It will involve 100 adults who recently had a stroke. One group will do 40 hours of brain exercises over 8 weeks, while the other…

This study is observing whether a nurse-led support program helps stroke survivors and their caregivers after leaving the hospital. It follows 130 participants in Tanzania for six months to see if the program improves patients' confidence in managing their health, their quality o…

This study aims to find out if a clot-removal procedure is safe and effective for stroke patients who already had moderate-to-severe disabilities before their stroke. It will compare the procedure plus standard medical care against standard medical care alone. The goal is to dete…

This large Phase 3 trial is testing which of two clot-busting drugs works better for people having a major stroke caused by a large blocked artery. About 850 patients will be randomly assigned to receive either the standard drug (alteplase) or a newer alternative (tenecteplase) w…

This study is testing whether a simple, widely available CT scan works as well as more complex imaging for selecting stroke patients who need a procedure to remove a blood clot. Researchers will compare outcomes for patients selected using each method to see if the simpler approa…

This study is testing a new type of MRI scanner to see if it can better identify which parts of the brain might recover after a stroke. Researchers will compare the new scanner to standard MRI scans in 40 people who have just had a stroke. The goal is to see if the new technology…

This study is testing whether adding low-cost virtual reality (VR) games to standard stroke therapy can help people recover arm movement better. It will involve 40 adults who have had a first-time stroke with moderate to severe arm weakness. Researchers will compare recovery betw…

This study aims to understand the precise timing of brain injury after a stroke by measuring a specific protein (BD-tau) in the blood. Researchers will take blood samples every hour for 48 hours from 100 patients who have just had a stroke. The goal is to learn exactly when brain…

This study aims to understand what factors lead to brain diseases like stroke and dementia by following 5,000 adults over many years. Participants, including those with a diagnosis, at high risk, or who are healthy, will regularly complete health questionnaires and interviews. Th…

This study aims to understand how well a proven emergency stroke treatment works in everyday hospital practice across the Asia-Pacific region. Researchers will observe 350 adult patients who have a severe stroke caused by a major blocked brain artery. The goal is to identify fact…

This study aims to test how reliable a new, standardized physical exam method is for identifying joint motion problems. Researchers will compare joint motion in healthy volunteers, people who had a mini-stroke (TIA), and people who had a recent stroke. The goal is to see if this …

This study aims to collect and standardize information on how well patients recover three months after having a procedure to remove a blood clot from the brain during a stroke. It will follow 5,000 people who have had this endovascular treatment. The goal is to better understand …

This study aims to understand if COVID-19 vaccines affect brain health, specifically looking for signs of stroke or dementia. Researchers in Hong Kong will follow 500 healthy adults, comparing brain scans and memory tests from before and after vaccination to those from unvaccinat…

This study aims to learn more about strokes by analyzing the blood clots that cause them. Researchers will collect clots removed from 1,200 stroke patients and compare them to blood samples and patient health records. The goal is to see if the clot's makeup can help explain why t…

This study aims to validate tests that can predict how well a person's arm will recover after a stroke. Researchers will use brain scans and a safe, non-invasive brain stimulation technique on about 657 recent stroke patients. The goal is to create reliable tools to identify whic…