Brain zaps may cut pneumonia risk after stroke
NCT ID NCT06123650
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether adding a non-invasive brain stimulation technique (rTMS) to standard swallowing therapy can reduce pneumonia in stroke patients who have trouble swallowing. About 70 adults aged 49-65 with moderate to severe swallowing problems after a stroke will be enrolled. The goal is to see if the stimulation lowers the risk of lung infections, a common and dangerous complication after stroke.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If it works, this could offer a way to lower pneumonia risk in stroke patients with swallowing difficulties, potentially reducing deaths and complications.
- What could go wrong
- This is a small, early-stage trial (70 people) testing a device, so results may not apply widely. The treatment is short-term and may not prevent pneumonia in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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49 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. All the patients were diagnosed of stroke oropharyngeal dysphagia by a neurologist. Sever to moderate dysphagia (GUSS 0-14). 2. Severity of stroke ranged from mild to moderate according to NIHSS score (NIHSS less than or equal 16). 3. Patients' age ranged from 49 to 65 years old. 4. Patients had the ability to understand and follow instructions. 5. Patients were able to sit in upright position. Exclusion Criteria: 1. History of previous stroke. 2. History of any swallowing problem. 3. History of any head and neck surgery or tumor that causes swallowing dysfunction. 4. Any lung disease or pneumonia on admission. 5. Patients with cognitive deficits or disturbed conscious level. 6. Patients on mechanical ventilator. 7. Patients with sensory or global aphasia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Physical Therapy, Cairo University
RECRUITINGGiza, Giza Governorate, 11432, Egypt
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