Cairo University

This study tests whether metformin, a diabetes drug, can shrink or prevent precancerous mouth patches called oral leukoplakia. Researchers will give 34 adults a metformin gel applied to the lesion plus a metformin pill, or placebos. The goal is to see if the combination reduces l…

This study tests whether two different drug mixtures—ketofol (ketamine plus propofol) and ketodex (ketamine plus dexmedetomidine)—can prevent postoperative delirium (sudden confusion) in elderly patients after open cancer surgery in the pelvis or abdomen. The trial will enroll 18…

This study tests whether giving a small dose of epinephrine (adrenaline) right after spinal anesthesia, followed by a steady infusion, can prevent blood pressure drops during cesarean sections. Researchers will compare this approach to epinephrine infusion alone in 100 women aged…

This study tests whether adding a non-invasive brain stimulation technique called rTMS to standard swallowing therapy can reduce pneumonia in stroke patients with swallowing problems. About 70 adults who recently had a stroke and have moderate to severe swallowing difficulty will…

This study tests two drugs, ergometrine and carbetocin, both injected into the uterus during surgery to remove fibroids. The goal is to see which one reduces blood loss more effectively. Forty women having abdominal myomectomy will be randomly assigned to receive one of the drugs…

This early study compares a mouthwash containing tropolone to the standard chlorhexidine 0.2% mouthwash for reducing bacteria that cause cavities. Thirty healthy adults aged 18–45 will stop their usual oral hygiene for a few days, then use one of the mouthwashes. Researchers will…

This study tests a new way to treat multiple receding gums using a substance made from the patient's own blood (Alb-PRF) compared to the standard connective tissue graft. 26 adults with good oral hygiene will be treated and followed to see how much gum coverage is achieved. The g…

This study tests whether combining task-oriented training with functional electrical stimulation (FES) can improve balance and ankle strength in children aged 6-9 with hemiparesis (weakness on one side). Thirty-six children will participate in a structured exercise program three …

This study tests a connective tissue graft (CTG) to thicken and reshape the gum in areas where a tooth is missing. Twenty adults with a single missing front tooth will get the graft, and researchers will compare results between those who already have a bridge and those who don't.…

This trial compares two types of ceramic veneers—ultra-translucent zirconia and lithium disilicate—in 10 adults aged 18–50. The goal is to see which one looks better, lasts longer, and makes patients happier. Participants must have healthy gums and teeth needing veneers for gaps,…

This study tests two dental devices—a vertical holding appliance and a Zachrisson transpalatal arch—to correct anterior open bite in children aged 6-12. The goal is to see which works better for closing the gap between upper and lower front teeth. Researchers will measure changes…

This study compares methotrexate alone versus methotrexate plus the antidepressant escitalopram in 40 adults with moderate to severe psoriasis and depression or anxiety. Over six months, researchers will measure skin improvement and mental health changes to see if the combination…

This study compares two surgical methods for treating high anal fistulas, a condition where an infected tunnel forms between the anal canal and skin. The trial will enroll 64 adults and measure which surgery leads to better healing and fewer complications. The goal is to find a s…

This study tests whether adding a physical activity program to standard care can improve health in older women who have three conditions: underactive thyroid (hypothyroidism), glaucoma (high pressure in the eyes), and fatty liver. Researchers will measure changes in eye pressure,…

This study uses a special ultrasound technique called shear wave elastography to measure how stiff the sciatic nerve is during two different leg movement sequences. Researchers will compare 30 people with sciatica (low back pain with leg pain) to 30 healthy volunteers. The goal i…

This study tests whether giving magnesium sulphate to pregnant women at high risk of preterm birth can protect their babies from cerebral palsy. About 138 women between 32 and 35 weeks of pregnancy will receive either magnesium or a placebo before delivery. Researchers will then …

This study looks at whether a brief digital abstinence intervention can help nursing students reduce distractions and improve time management. 80 undergraduate nursing students will either limit or stop non-academic smartphone use for a set period. Their time management skills wi…

This study compares two blood-derived gels (Alb-PRF and PRF) against a standard gelatin sponge for reducing pain and improving healing after a gum graft. 39 adults needing a gum graft will be randomly assigned to one of three treatments applied to the wound. Pain, healing, and co…

This study compares two ultrasound-guided nerve blocks—rhomboid intercostal block and erector spinae plane block—for pain control after lung cancer surgery. Sixty adults undergoing thoracotomy will receive one of the two blocks with bupivacaine. Researchers will measure morphine …

This study tests whether walking on a special sensory walkway can improve how children with spastic diplegic cerebral palsy walk. Forty-four children aged 5 to 7 will either receive standard physical therapy or standard therapy plus sensory walkway training for three months. Rese…

This study compares two drugs, aminophylline and furosemide, to see which one helps adults produce more urine after heart surgery. About 106 patients having elective heart procedures will be randomly assigned to receive one of the drugs. The main goal is to measure urine output t…

This study tests whether focused shock wave therapy can reduce pain and improve nerve function in people with cervical radiculopathy, a condition where a pinched nerve in the neck causes pain and weakness in the arm. Eighty adults aged 36 to 46 with confirmed disc problems will r…

This study tests whether a hands-on technique called gastrocnemius myofascial release (a type of calf muscle massage) can reduce pain and improve physical function in women aged 45-55 with knee osteoarthritis. Thirty participants will receive either the real treatment or a sham v…

This study tests whether adding a low dose of intravenous ketamine to standard spinal anesthesia can prolong numbness in elderly patients undergoing leg surgery. About 61 participants aged 65 and older will be randomly assigned to receive either ketamine or a placebo (saline) alo…

This study compares two physical therapy approaches to help people who recently had a stroke regain arm function. One method focuses on training individual muscles, while the other uses natural movement patterns. Forty participants will receive 12 weeks of therapy, and researcher…

This study tests whether watching a short educational video about how TENS works can enhance its pain-relieving effect in people with acute low back pain. Forty adults will receive standard TENS and exercise therapy, with half also viewing the video. The main goal is to see if a …

This study tests whether simple brain gym exercises—like drinking water, cross crawls, and deep breathing—can improve balance and quality of life in children aged 6 to 8 with spastic diplegia, a type of cerebral palsy. Forty-four children will be split into two groups: one doing …

This study tests whether high-intensity laser therapy or high-power pain threshold ultrasound works better for easing pain and improving movement in people with plantar fasciitis. Sixty adults aged 30 to 60 with heel pain will receive one of these treatments or standard care thre…

This study tests a manual therapy technique called saphenous nerve release to see if it can reduce pain, improve balance, and restore function in people with patellofemoral pain syndrome (a common cause of front knee pain). The trial will include 36 adults aged 18 to 35 with pers…

This study looks at whether adding core stability exercises or cognitive training to standard rehab can improve balance and control in people with chronic ankle instability. About 45 adults aged 18–30 with a history of ankle sprains will take part. The goal is to find better ways…

This study compares two types of ultrasound-guided nerve blocks to standard pain management for children aged 5-13 having their tonsils removed. The goal is to see if these blocks can delay the need for extra pain medicine and improve recovery. Forty children will take part, and …

This study compares two types of exercises—breathing exercises and deep neck flexor training—added to standard care for people with chronic neck pain. Researchers will measure pain, neck movement, muscle endurance, and daily function in 66 adults aged 18 to 35. The goal is to fin…

This study tests if a mild electrical patch placed on the skin (called TENS) can prevent breathing problems after weight-loss surgery in people with severe obesity. About 70 participants will be randomly assigned to receive either TENS or a fake device. The main goal is to see if…

This study tests whether using calming words (verbal analgesia) can reduce pain during copper IUD insertion in women who have only had C-sections and no vaginal deliveries. About 88 women will be randomly assigned to receive either verbal reassurance or standard care. The main go…

This study looks at how often the diaphragm — the main muscle used for breathing — becomes weak after a C-section in women with severe preeclampsia. Researchers will use ultrasound to measure diaphragm movement before and 24 hours after surgery in 52 women. The goal is to find ou…

This study tests whether measuring how much a small chest muscle thickens during breathing can help doctors decide the best time to remove a breathing tube. Two hundred critically ill patients on ventilators will be randomly assigned to have their weaning decision guided by this …

This study looks at children's baby teeth that were previously treated for cavities with either silver diamine fluoride (SDF) plus a filling or just a filling alone. After the teeth are naturally lost or extracted, researchers will examine them under a microscope to see how the i…

This study looks at how bariatric surgery changes sexual function, sex hormones, mood, and quality of life in 40 women with severe obesity. Participants will complete questionnaires and give blood samples before surgery and 6 months after. Their partners will also report on their…

This study looks at a protein called Surfactant Protein D (SP-D) in the gum fluid of people with gum disease (periodontitis). Researchers will measure SP-D levels before and 6 months after a gentle, non-surgical cleaning treatment. The goal is to see if SP-D levels change with tr…