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Gum graft recovery: could a blood gel beat the standard treatment?

NCT ID NCT06567548

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two blood-derived gels (Alb-PRF and PRF) against a standard gelatin sponge for reducing pain and improving healing after a gum graft. 39 adults needing a gum graft will be randomly assigned to one of three treatments applied to the wound. Pain, healing, and color match will be tracked for 28 days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Albumin platelet-rich fibrin (Alb-PRF) and platelet-rich fibrin (PRF)
What this could lead to
If it works, this could offer a better way to reduce pain and speed up healing after gum graft surgery.
What could go wrong
This is a small, early-stage trial with only 39 participants, so results may not apply to everyone. The benefit over existing methods may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 39 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients in need of free gingival graft 2. Medically free patients 3. Adult patients above 18 years old. 4. Patients accepting a 1-month follow-up period (cooperative patients). 5. Patients who will provide an informed consent. Exclusion Criteria: 1. Smokers 2. Pregnant and lactating women 3. Patients with poor oral hygiene 4. Patients who had previous periodontal surgery in the area of interest

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Palate; wound

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cairo University

    NOT_YET_RECRUITING

    Cairo, Cairo Governorate, 12613, Egypt

  • Cairo University

    RECRUITING

    Cairo, Cairo Governorate, 12613, Egypt

  • Cairo University

    RECRUITING

    Giza, Cairo Governorate, 12567, Egypt

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