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Weight loss surgery may boost sex life and mood, new study hopes to prove

NCT ID NCT07446972

Knowledge-focused Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 40 women with severe obesity who are scheduled for weight loss surgery. Researchers will measure changes in sexual function, sex hormone levels, mood, and quality of life before surgery and 6 months after. Partners will also report on their own sexual health. The goal is to understand how surgery affects overall well-being, not just weight.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better counsel patients about improvements in sexual health and quality of life after weight loss surgery.
What could go wrong
This is a small, early observational study with only 40 participants, so results may not apply to everyone. It measures changes at 6 months, so long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Morbidly obese female patients of childbearing age (18-50 years) with stable, sexually active intimate partner relationships, scheduled for primary bariatric surgery (sleeve gastrectomy or Roux-en-Y gastric bypass) at Cairo University Hospital, Egypt. Participants are recruited from the bariatric surgery clinic during routine pre-operative assessment.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female gender * Age 18-45 years (childbearing period) * Body Mass Index (BMI) ≥40 kg/m² or ≥35 kg/m² with obesity-related comorbidities, meeting international criteria for bariatric surgery * Scheduled for primary bariatric surgery (sleeve gastrectomy or Roux-en-Y gastric bypass) * Presence of a stable, sexually active intimate partner relationship * Sexually active * Willingness to participate and provide informed consent * Ability to complete Arabic-language questionnaires Exclusion Criteria: * Women who are not sexually active * Post-menopausal women (amenorrhea ≥12 months without other cause) * Current pregnancy or lactation * History of medication use that can interfere with sexual function, including: * Antidepressants * Antipsychotics/psychotropic drugs * Beta-blockers * Spironolactone * Hormonal contraceptives (unless stable for ≥3 months and continued throughout study) * Hormone replacement therapy * Major uncontrolled medical conditions: * Chronic heavy smoker (smoking index ≥400 pack-years) * History of pelvic floor surgery or gynecological malignancy * Partner with known erectile dysfunction or use of erectile dysfunction medications * Previous bariatric surgery (revisional procedures) * Inability or unwillingness to provide informed consent

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Conditions

The condition(s) this trial relates to.

morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Morbid obesity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Medicine Cairo University

    RECRUITING

    Cairo, Al-Manial Cairo, 11956, Egypt

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