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Tiny study peers inside Kids' teeth to see how cavity treatment works

NCT ID NCT07586631

Knowledge-focused Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at children's baby teeth that were previously treated for cavities with either silver diamine fluoride (SDF) plus a filling or just a filling alone. After the teeth are naturally lost or extracted, researchers will examine them under a microscope to see how the inner pulp tissue reacted. The goal is to understand the long-term effects of SDF on the tooth's nerve and blood supply. Only 6 children are enrolled, making this a very small, early-stage investigation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer
What this could lead to
If successful, this study could provide a better understanding of how SDF affects the tooth's inner pulp, potentially improving cavity treatments for children.
What could go wrong
This is a very small study (only 6 participants) and is observational, not testing a new treatment. It may not provide conclusive results or apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 6 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children with primary teeth that have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or Resin Modified Glass Ionomer alone.

Ages

7 to 10 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Primary teeth that have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or Resin Modified Glass Ionomer alone. Exclusion Criteria: * Treated primary teeth with clinical or radiographic signs of infection

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Conditions

The condition(s) this trial relates to.

dentin caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Silver diamine fluoride

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    RECRUITING

    Cairo, Egypt

More trials for these conditions

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