Silver liquid could save Seniors' teeth without drilling
NCT ID NCT07194629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a special silver liquid (silver diamine fluoride) can stop tooth decay in elderly people living in nursing homes. Sixty participants will either get the silver treatment or a placebo, and their teeth will be checked after 6 and 12 months. The goal is to improve oral health and quality of life without the need for drilling or complex dental procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Elderly of 65 years of age or older living at a long-term care facility targeted by the study. * Should present at least one coronal or radicular active carious lesion that is asymptomatic, untreated, or a residual lesion under a restoration, and without pulp involvement. Exclusion Criteria: * Participants with inadequate collaboration that may impede dental examination or treatment. * Participants with cardiac valve prostheses, a history of bacterial endocarditis, or valve disease following a heart transplant. * Completely edentulous elderly, as well as elderly presenting with no coronal or radicular caries * Participants allergic to silver, fluoride or ammonia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHSLD Alfred Desrochers
Montreal, Quebec, H3W2P2, Canada
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Institut universitaire de gériatrie de Montreal
Montreal, Quebec, H3W1W5, Canada
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Université de Montréal
Montreal, Quebec, H3T1J4, Canada
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