Can a detailed health check predict who thrives after a stem cell transplant?
NCT ID NCT06946654
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers are studying whether a comprehensive geriatric assessment can identify risks and improve outcomes for older adults undergoing allogeneic hematopoietic stem cell transplantation. The study enrolls 176 patients aged 55 and older with blood disorders who are eligible for a donor stem cell transplant. Before transplant, participants complete evaluations of physical function, nutrition, mood, thinking, social support, and medications, along with disease and donor factors. The goal is to see which factors predict transplant-related mortality, engraftment, and graft-versus-host disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- geriatric assessment, a structured evaluation of health, function, and support before transplant
- What this could lead to
- If the assessment predicts who will do well, doctors could tailor transplant decisions and supportive care for older patients, potentially lowering complications and deaths.
- What could go wrong
- This is an observational study, so it cannot prove that using the assessment changes outcomes. The findings may not apply to all transplant centers or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 176 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Elderly patients with hematologic disorders with established indications for transplantation, including malignant and non-malignant hematologic diseases.
- Ages
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55 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * (a)Age ≥55 years. * (b)Hematologic disorders with established indications for transplantation, including malignant and non-malignant hematologic diseases. (c)Willingness to provide informed consent. Exclusion Criteria: (a)Pregnancy. (b) Uncontrolled active infection. (c) Lack of informed consent. (d)Deemed ineligible for transplantation after investigator assessment
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Get notified about this study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Peking University People's Hospital
RECRUITINGBeijing, China
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