ELDERLY

This study compares two seasonal flu vaccines—one with an extra ingredient to boost the immune response (adjuvanted) and one without—in 200 adults aged 65 and older who also have chronic medical conditions like diabetes or heart disease. The goal is to see which vaccine triggers …

This study looks at the best way to prevent another stroke in older adults who have a small hole in the heart (PFO) and had a stroke from an unknown cause. It compares two treatments: closing the hole with a device or taking blood thinners. The study will follow 400 people aged 6…

This study is testing whether a team of doctors from different specialties can create better treatment plans for older adults (ages 60-90) with lung cancer. Each patient will get a personalized plan based on a full health assessment. The goal is to see if this team approach helps…

This study tests whether giving elderly patients with kidney disease a personalized amount of fluids, guided by a lung water monitor, can prevent acute kidney injury after a heart imaging procedure called coronary angiography. About 320 participants aged 60 and older with chronic…

This early-stage study tests whether a combination of two experimental drugs, GI-102 and GIB-7, can improve immune function and other signs of aging in healthy adults and cancer survivors. The trial involves 15 participants and lasts 8 weeks, focusing on safety and changes in imm…

This study tests whether metformin, a common diabetes medicine, can improve memory and thinking in overweight or obese older adults with mild cognitive impairment (MCI). Researchers will give metformin or a placebo to 54 people aged 60-75 for 26 weeks. They will use brain scans a…

This study tests a chatbot that guides people through telling their life story to improve emotional well-being. It includes healthy adults, people with mental health conditions in residential care, and older adults aged 65+. The chatbot is not a treatment but a tool to support em…

This study looks at whether using a positive airway pressure (PAP) machine at night can improve thinking, sleepiness, and quality of life in older veterans (age 60+) who have both COPD and obstructive sleep apnea—a combination called overlap syndrome. Researchers will measure mem…

This study looks at whether adding local muscle vibration to standard rehabilitation can help elderly patients (75+) recover muscle strength, mobility, and reduce pain after hip fracture surgery. About 25 participants will receive vibration sessions five times a week for four wee…

This study looks at how well the body digests and uses protein from peas in healthy young and older adults. Researchers will compare vegetarians and meat-eaters to see if diet or age affects protein absorption. The goal is to learn more about plant protein quality to help design …

This study watches 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like delirium (sudden confusion). Researchers collect blood samples and health info to build a risk prediction model. The goal is to better understand and eventually …

This study looks at why some older adults improve their muscle strength with exercise while others don't. Researchers will track 900 people aged 60 and older, measuring muscle power and blood markers before and after different physical activity programs. The goal is to learn how …

This study looks at whether certain blood markers and brain scans can help predict which older adults with memory loss or frailty will need to visit the emergency room within six months. Researchers will follow 110 participants aged 65 and older who have lost some independence. T…

This study looks at whether it is safe to stop antibiotics early in people aged 65 and older who are hospitalized with a viral lung infection. Many older patients receive antibiotics even when they have a virus, which can lead to side effects and antibiotic resistance. The resear…

This study looks at whether singing, alone or in a group, is a practical activity for older adults with coronary artery disease. Researchers want to see if people will stick with it and if it might help lower heart disease risk. The study involves 32 participants and focuses on h…

This study looks at whether older men (70+) with prostate cancer who have been on hormone therapy for over three years can stop taking it. The idea is that their bodies may no longer produce testosterone, making the treatment unnecessary. Researchers will monitor testosterone lev…