ELDERLY

This study aims to see if different combinations of mental exercises (like puzzles) and physical exercise can help older women maintain their thinking skills, memory, and quality of life as they age. Researchers will test 124 women aged 60 and older who do not have severe memory …

This study is preparing for a larger trial to see if regular singing can improve blood vessel health and lower future heart disease risk in older adults who already have coronary artery disease. Researchers will test whether group singing (in-person or virtual) or solo singing is…

This study is testing if a simple liquid treatment can stop cavities in elderly people living in nursing homes who have trouble brushing their teeth. Researchers will apply a silver fluoride liquid to cavities and check if it hardens them and stops decay over a year. The goal is …

This study aims to find the best way to manage atrial fibrillation (AF), a common irregular heartbeat, in people aged 78 and older. It will randomly assign 282 participants to receive either a catheter ablation procedure or optimized medication therapy. Over two years, researcher…

This study aims to see which type of exercise is better for preventing falls in older adults. Researchers will compare a strength-building program with a functional training program that mimics daily activities. The goal is to improve balance and mobility for people aged 65 and o…

This study aims to see if using a common intravenous pain medication (acetaminophen) is better than a stronger opioid (sufentanil) at preventing confusion and delirium in older patients after non-heart surgery. It will involve over 1,000 patients aged 60+ in intensive care units …

This study aims to see if a specific way of giving anesthesia drugs can help protect older patients' memory and thinking skills after surgery. Researchers will compare two different levels of anesthesia depth, both delivered by a precise IV pump that mixes two key drugs in a fixe…

This study aims to find the best way to predict if a patient aged 75 or older visiting a French emergency room will need to be admitted to the hospital. Researchers will test an existing prediction tool (GAPS) and create a new one (PROFACTHOS) using medical records from nearly 1,…

This study aims to understand if having less muscle mass is linked to a higher chance of serious bleeding in people aged 70 and older who are taking common blood-thinning medications (like Apixaban or Rivaroxaban). Researchers will compare the muscle mass of 110 participants—some…

This study looks at PET-CT scan results in elderly patients (age 60+) with lymphoma to better understand how the cancer appears on imaging. Researchers will analyze 63 patients' scans to identify patterns that might help with diagnosis and predicting outcomes. The goal is to impr…

This study aims to find out if a quick frailty screening tool used in the emergency room can identify which elderly patients are most likely to have unsafe or inappropriate prescriptions and dangerous drug interactions. Researchers will collect medical data from 300 patients aged…

This study aims to understand how a single dose of the drug anaprazole sodium is processed by the body and how safe it is in specific groups of people. It will enroll about 60 adults, including healthy volunteers, elderly people, and people with moderate liver or kidney problems.…