Could a Pre-Surgery nerve block speed up recovery after hip fracture?
NCT ID NCT07762846
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether giving a nerve block called a fascia iliaca compartment block (FICB) right after hospital admission, before hip fracture surgery, can improve recovery in patients aged 65 and older. Half of the 144 participants will receive the early block, while the other half gets standard pain care once in the operating room. The study measures quality of recovery, pain scores, sleep, opioid use, delirium, and hospital stay length to see if early pain control makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ultrasound-guided fascia iliaca compartment block (FICB) with liposomal bupivacaine
- What this could lead to
- If early FICB works, it could become a standard pre-surgery pain management step for elderly hip fracture patients, leading to faster recovery and shorter hospital stays.
- What could go wrong
- This is a single-center trial with 144 participants, so results may not apply broadly. The block carries rare risks like bleeding or nerve damage, and its benefit over standard care is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 65 years * Diagnosis of unilateral hip fracture (including femoral neck fracture or intertrochanteric fracture) confirmed by any imaging modality (X-ray, CT, or MRI) * Scheduled for hip fracture surgery under general anesthesia with endotracheal intubation (including total hip arthroplasty, hemiarthroplasty, intertrochanteric intramedullary nail fixation, closed reduction and internal fixation, etc.) * American Society of Anesthesiologists (ASA) physical status classification I-III * Able to provide written informed consent personally or via a legally authorized representative * Able to communicate normally in Chinese Exclusion Criteria: * Known allergy to ropivacaine, bupivacaine, or liposomal bupivacaine * Presence of any contraindication to nerve block, including but not limited to: nerve injury, coagulopathy, severe infection at the injection site, exudate at the injection site, etc. * Pre-existing psychiatric or neurological disorders, including but not limited to: depression, severe central nervous system depression, Parkinson's disease, basal ganglia lesions, schizophrenia, epilepsy, Alzheimer's disease, myasthenia gravis * Pre-existing severe cardiac, pulmonary, hepatic, or renal dysfunction, including but not limited to: history of heart failure, requiring dialysis, etc. * Inability to communicate preoperatively (e.g., coma, dementia) * Preoperative pain score \< 4 on Visual Analog Scale (VAS) or chronic/old hip fracture * Currently participating in another interventional clinical trial * Any other condition that, in the opinion of the investigator, would preclude evaluation of the therapeutic response or make it unlikely that the patient will complete the expected treatment course and follow-up
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Renji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a nerve block stop pain months after hysterectomy?