Cairo University

This early study will test whether using a miswak chewing stick (from the Salvadora persica plant) can reduce gum inflammation better than a regular toothbrush in people with moderate gum disease (periodontitis). Researchers will measure inflammatory markers in gum fluid from 24 …

This study tests two bone grafting materials to see which better preserves the jawbone after a molar is pulled. One material is made from the patient's own extracted tooth, mixed with a blood concentrate; the other uses a standard bone substitute mixed with the patient's blood. T…

This study tests whether narrow-band ultraviolet B (NB-UVB) light therapy can help people with ringworm infections that don't get better with standard antifungal drugs. The trial will enroll 36 adults who have had at least two relapses in the past six months. Half will receive UV…

This study compares two dental procedures for treating deep cavities in baby molars of children aged 6-8. One group gets a partial nerve treatment (pulpotomy) using a special cement, while the other gets a full root canal (pulpectomy) with a medicated paste. Researchers will trac…

This study tests whether silver diamine fluoride or silver fluoride, with or without a special LED light, can stop early cavities in the back teeth of young adults. About 366 high-risk dental students will receive one of four treatments, and researchers will check if the cavities…

This study tests whether a 'sticky bone' made from a patient's own blood concentrate and bone graft material can improve healing after impacted wisdom tooth removal. Ten adults will receive the sticky bone in the extraction socket right after surgery. Researchers will measure bon…

This study tests whether adding ephedrine to norepinephrine can better prevent low blood pressure in women having planned C-sections under spinal anesthesia. 260 healthy pregnant women will receive either the drug combo or norepinephrine alone. The goal is to see if the combo red…

This study compares two surgical techniques for repairing bilateral alveolar clefts (gaps in the upper jaw) using bone grafts from the hip. Twenty participants will receive either a solid bone block or loose bone chips. The goal is to see which method provides better bone volume …

This study compares two types of dental fillings for cavities in the back teeth. Researchers will test a bulk-fill flowable resin against a submicron hybrid resin in 25 patients over 18 months. The goal is to see which filling performs better in terms of shape, comfort, and appea…

This study tests a new root canal filling made from zinc oxide and ozonated olive oil against a standard paste (Metapex) in children aged 3-5 with cavities in their front teeth. Over 12 months, dentists will check for pain, swelling, and healing on X-rays. The goal is to see if t…

This study tests a new, gentler way to remove a tooth before placing a dental implant. Instead of wiggling the tooth out, doctors use a special tool (Benex system) to pull it straight up, which may cause less damage to the surrounding bone and gum. The goal is to see if this meth…

This study compares a new, less invasive method of fixing the upper jaw after surgery to the standard approach. In the new method, surgeons use custom 3D-printed plates placed through a smaller incision on the nasal buttress only, instead of the usual larger incision on both the …

This study compares two surgical methods to treat receding gums on a single tooth. One method uses a small tunnel under the gum, and the other adds a tissue graft. The goal is to see which covers the exposed root better and looks more natural. The study will involve 24 adults wit…

This study tests whether placing a Concentrated Growth Factor (CGF) plug—made from the patient's own blood—into the empty socket after a simple tooth extraction can reduce pain and help preserve bone density. Ten healthy adults aged 20 to 50 who need a single tooth pulled will ta…

This study compares a new, easier-to-use tooth-colored filling material to a standard one for cavities between back teeth. Fifty adults aged 18-64 with cavities will receive one of the two fillings and be checked after 12 months for how well they hold up, look, and feel. The goal…

This study compares two techniques for preserving the jawbone after a tooth is pulled. Thirty adults with a small hole in the front of the socket will receive either a 'socket-plug' or 'ice cream cone' method using bone-like material. The goal is to see which better maintains bon…

This study tests a dental implant procedure for people with thin jawbone. Surgeons will place the implant and use the patient's own bone chips and special growth factor membranes to rebuild the bone around it. The study will check bone density and gum thickness before, right afte…

This study tests whether adding low-dose steroid pills to a standard vitiligo skin-cell transplant surgery helps prevent a pale ring around the treated area and improves overall skin color restoration. About 60 people with stable vitiligo will be randomly assigned to get surgery …

This study tests whether giving a combination of three drugs (oxytocin, tranexamic acid, and an ergot derivative) right after a C-section can prevent postpartum hemorrhage better than the standard single drug, carbetocin. The trial will enroll 80 women undergoing planned or unpla…

This study tests if using a diode laser before applying a tooth-colored sealant helps it stick longer and prevent cavities better. About 111 young adults aged 17-22 will get sealants on their back teeth, with or without laser pre-treatment. Researchers will check sealant retentio…

This study will test a new self-sticking dental material against a standard sealant to see which better prevents cavities in children's permanent molars. About 88 healthy kids aged 6-8 with high cavity risk will take part. The goal is to find out which material stays on teeth lon…

This study tests a new gel that dissolves tooth decay without drilling, aiming to reduce patient anxiety. Eighty adults with cavities in lower molars will be randomly assigned to either the gel or a standard drill. The main goal is to see which method causes less pain and discomf…

This study will test whether adding a special massage-like technique (instrument-assisted soft tissue mobilization) to a standard manual therapy (Mulligan) can better relieve cervicogenic headache — a headache that starts from the neck. Sixty adults with chronic neck-related head…

This study tests whether adding latissimus dorsi (upper back) strengthening to standard gluteal exercises can better reduce pain and improve pelvic alignment in people with sacroiliac joint dysfunction. Forty adults aged 35-55 with chronic low back pain from this condition will b…

This study tests whether a device called TECAR, which uses radio-frequency energy, can reduce pain and improve finger movement in 40 adults who recently had flexor tendon repair surgery. Participants will receive the therapy in multiple sessions over six weeks, and their finger j…

This study will test whether a gentle nerve-sliding technique can reduce pain, improve function, and help balance in people with chronic leg pain from a pinched nerve in the lower back (lumbar radiculopathy). Twenty-eight adults with symptoms lasting 3 to 18 months will receive e…

This study tests whether special kaleidoscope glasses can reduce pain and anxiety in children aged 4-6 during dental pulp therapy (a baby root canal). The glasses show colorful, changing patterns to distract the child. Researchers will compare the glasses to the Tell-Show-Do meth…

This study tests a manual therapy technique called intercostal mulligan mobilization to reduce shoulder pain and improve range of motion in women who had a mastectomy at least 3 months ago. Forty participants will receive either this therapy plus standard exercises or exercises a…

This study tests whether a device that sends mild electrical pulses to a nerve in the ankle (TTNS) can reduce pain and distress from period cramps. Thirty-six women with primary dysmenorrhea will receive either standard care (heat packs and stretches) or standard care plus TTNS f…

This study compares two treatments for dentin hypersensitivity (tooth sensitivity). One group gets a special varnish (CPP-ACPF) alone, the other gets the varnish plus a low-level laser treatment. 70 adults with sensitive teeth will rate their pain before and after. The goal is to…

This study compares two non-invasive nerve stimulation techniques—TENS (electrical pads on the skin) and rTMS (magnetic pulses on the scalp)—for reducing pain and improving function in people with cervical radiculopathy (a pinched nerve in the neck causing arm pain). Fifty adults…

This study tests whether tension and trauma releasing exercises (TRE) can help people with high blood pressure sleep better and feel better day-to-day. Forty adults aged 50-65 with stage 1 hypertension will do supervised TRE sessions for 8 weeks. Researchers will measure changes …

This study tests whether doing virtual reality exercise during dialysis can help patients with end-stage kidney disease keep their electrolytes (sodium, potassium, calcium, phosphorus) in a healthier range. Forty adults on regular dialysis will either do 30 minutes of VR cycling …

This study tests whether adding neck stabilization exercises to standard physical therapy can reduce pain and improve shoulder function in people with shoulder impingement syndrome. Forty-two adults aged 20-40 with shoulder pain for at least three months will be split into two gr…

This study tests whether a set of jaw exercises called 'condylar remodeling exercises' can improve how well people sense the position of their neck and jaw. The trial will include 40 adults with forward head posture and jaw pain. Participants will do the exercises and be measured…

This study tests whether reflexology (foot massage) or progressive muscle relaxation can reduce fatigue in people on hemodialysis. Sixty adults aged 50-70 with moderate to severe fatigue will be split into three groups: reflexology, relaxation, or usual care. Both techniques are …

This study tests whether pulsed electromagnetic field (PEMF) therapy can reduce itching in people with burn scars. Forty adults aged 25-40 with moderate to severe itch will receive either PEMF plus standard care or standard care alone. The main outcomes are changes in itch intens…

This study tests whether a gentle, non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve sleep and reduce anxiety in adults over 60 who have chronic insomnia. Sixty participants will receive tACS sessions, and researchers …

This study looks at whether core stability training can help manual workers with shoulder impingement syndrome. Forty workers will either do core exercises or standard physiotherapy. The goal is to see if core training improves shoulder function better than usual care.

This study tests whether using a virtual reality headset for 30 minutes each week can reduce depression in teenage girls aged 13-18. Half the participants will use VR, while the other half take standard antidepressant pills. Researchers will measure changes in depression scores a…

This study compares two types of nerve blocks—erector spinae plane block and thoracic paravertebral block—for pain control after chest surgery. About 86 adults undergoing open chest surgery will receive one of the blocks with a numbing medicine (bupivacaine) to see which reduces …

This study compares two drugs, magnesium sulfate and dexmedetomidine, used alongside total intravenous anesthesia during lumbar spine surgery. The goal is to see which drug helps patients wake up and have their breathing tube removed faster. Forty adults scheduled for spine surge…

This study compares two vibrating devices (Vibraject and Dental Vibe) against a standard syringe for giving numbing shots in the mouth to children aged 6-8. The goal is to see if the vibration helps reduce pain during the injection. Ninety children who need dental work on lower b…

This study looks at whether doing aerobic or free exercises during dialysis sessions can reduce fatigue, improve walking ability, and help thinking in people with kidney failure. Sixty-nine adults aged 50 to 60 on maintenance hemodialysis will be assigned to different exercise ro…

This study tests whether a cream made from metformin, a common diabetes drug, can safely improve mild psoriasis. About 55 adults will apply either the metformin cream or a placebo twice daily for two months. Researchers will check skin biopsies and symptom scores to see if the tr…

This study compares two hands-on treatments—IASTM (using tools to massage muscles) and dry cupping (using suction cups)—for people with chronic neck pain from trigger points. 75 adults aged 20-50 will receive standard care (heat, TENS, exercises) plus one of these therapies for 4…

This study tests whether a relaxation method called autogenic training can help people on hemodialysis who suffer from restless leg syndrome, poor sleep, and fatigue. About 54 adults aged 45-55 will practice guided relaxation exercises for 8 weeks. Researchers will measure change…

This study will examine 50 existing 3D dental scans to measure the size and shape of the maxillary sinus and the greater palatine canal in the upper jaw. The goal is to create a guide that helps dentists and oral surgeons avoid complications during procedures like tooth extractio…

This study will measure balance in 80 people with three types of chronic low back pain: lumbar spondylosis, spondylolisthesis, and disc prolapse. Participants will stand on a special platform (Biodex Balance System) under different conditions, like with eyes open or closed, to se…

This study will check for dental problems like weak enamel, late tooth growth, and crooked teeth in Egyptian children aged 6-12 who are shorter than average. It will compare them to healthy children of the same age and background. The goal is to see if short stature is linked to …

This study will check if men and women on hemodialysis have different balance abilities. About 155 patients will do two simple tests: standing up from a chair and walking a short distance. No treatment is given — the goal is just to understand how balance may differ between gende…

This study will test whether an oral health education program can improve the dental health and quality of life of 70 Egyptian children aged 11-14 with hemophilia. The program teaches proper oral care tailored to their condition. Researchers will measure tooth decay, oral hygiene…

This study will survey 222 Egyptian parents of children aged 3-5 to see if parents' ability to find and use health information online is linked to their children's oral health, like cavities. Researchers will use a questionnaire to measure digital health literacy. The goal is to …

This study looks at how knee pain intensity relates to the knee's ability to sense its own position (proprioception) in people with patellofemoral pain syndrome. Researchers will measure pain and joint position error during a single-leg squat in 82 adults aged 18–35. The goal is …

This study will look at 51 adults aged 18 to 40 who have a shoulder blade that sits or moves differently (scapular dyskinesia) but feel no pain. Researchers will measure rotator cuff strength and the space inside the shoulder joint using ultrasound. The goal is to see if these fa…

This study looks at how smartphone addiction may affect core muscle endurance, spine curvature, and daily function in university students aged 18-25 who have had chronic low back pain for at least six months. Researchers will measure addiction levels, muscle endurance, and disabi…

This study will survey 215 Egyptian general dentists and specialists to assess their knowledge, attitudes, and clinical practices regarding resin cements for indirect intracoronal restorations. The goal is to identify gaps between evidence-based protocols and real-world use, help…

This study looks at how the curve of the lower spine relates to knee angle in college students who are addicted to their smartphones and have long-term low back pain. Researchers will measure spine curvature and knee movement using video software. The goal is to understand these …

This study looks at how to accurately measure muscle strength in 112 healthy women. Researchers compare two methods of adjusting strength results for body size. The goal is to find which method gives more consistent results, helping future studies and treatments.

This study reviews past dental implant cases to find a safer distance from the lower jaw nerve. Researchers will look at 100 patients who had implants placed very close to the nerve. The goal is to see if a new safety rule can help prevent numbness, tingling, or pain after the pr…

This study asks parents of children aged 2 to 12 about the challenges they face getting dental care and how satisfied they are with the services at a children's dental clinic in Cairo. Researchers will use surveys to find out what barriers exist and whether families are getting t…

This study looks at how the shape of the roof of the mouth (palate) and a person's age relate to the position and size of a nerve canal important for dental injections. Researchers will review 50 existing CBCT scans from Egyptian adults to measure palate height, width, and bone t…

This study tests whether training nurses to follow evidence-based guidelines can reduce infections and other complications in intensive care units (ICUs) in low- and middle-income countries. About 50 nurses will be trained and their patients' outcomes compared to usual care. The …