New study aims to cut opioid use after chest surgery
NCT ID NCT07437027
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks—erector spinae plane block and thoracic paravertebral block—for pain control after chest surgery. About 86 adults undergoing open chest surgery will receive one of the blocks with a numbing medicine (bupivacaine) to see which reduces the need for morphine in the first 24 hours. The goal is to find a better way to manage pain while using fewer opioids.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If successful, this could show that one nerve block provides better pain relief with less morphine after chest surgery.
- What could go wrong
- This is a small, early-stage study with only 86 participants, so results may not apply to everyone. The blocks may not differ significantly in pain control.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 86 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Mar 2026
An estimate. Start dates often move.
- Expected to finish
-
Jul 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients age between 18 and 70 . * Patients with ASAII and IIIstatus. * Patients undergoing open surgical Thoracotomy as in lobectomy, pneumonectomy, segmentectomy and decortication. * Gender both males and females. 2.Exclusioncriteria 1. Refusal of the patient. 2. Allergy to local anesthetic 3. Infection of the skin at the site of local infiltration 4. Cardiovascular problems (arrhythmia, heart block, SVT,AF, multiple extra systole). 5. Any contraindication to regional anesthesia as coagulopathy 6. Patients with chronic pain or on opoid medication preoperative
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Post-thoracotomy pain are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Kasr al aini hospital
Cairo, Kasr Alaini, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.