Which nerve block cuts opioid use after lung cancer surgery?

NCT ID NCT07040618

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Sep 02, 2026 · Updated 2 times

Summary

This study compares two ultrasound-guided nerve blocks—rhomboid intercostal block and erector spinae plane block—for pain control after lung cancer surgery. Sixty adults undergoing thoracotomy will receive one of the two blocks with bupivacaine. Researchers will measure morphine use, pain scores, and recovery over 24 hours to see which block works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If one block works better, it could mean less morphine and faster recovery after lung cancer surgery.
What could go wrong: This is a small, early-stage trial (60 people) comparing two established techniques. It may not show a clear winner, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients undergoing thoracotomy for lung cancer Age ≥ 18 years and ≤ 65 years ASA physical status II or III Body Mass Index (BMI) \> 20 kg/m² and \< 35 kg/m² Willing and able to provide informed consent Exclusion Criteria: Patient refusal ASA physical status IV Age \< 18 years or \> 65 years BMI \< 20 kg/m² or \> 35 kg/m² Known allergy or contraindication to local anesthetics or opioids used in the study History of chronic pain or psychological disorders Contraindications to regional anesthesia (e.g., local infection, coagulopathy, pre-existing peripheral neuropathy) Severe respiratory, cardiac, hepatic, or renal disease \-

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Which nerve block cuts opioid use after lung cancer surgery?

What the study statuses mean