Can a drug combo stop Post-Surgery brain fog in seniors?
NCT ID NCT07627906
First seen Jun 04, 2026 · Last updated Jun 22, 2026 · Updated 3 times
Summary
This study tests whether two different drug mixtures—ketofol (ketamine plus propofol) and ketodex (ketamine plus dexmedetomidine)—can prevent postoperative delirium (sudden confusion) in elderly patients after open cancer surgery in the pelvis or abdomen. The trial will enroll 180 people aged 60 and older and compare how many develop delirium within two hours after surgery. The goal is to find a safer anesthesia option that reduces brain complications in this high-risk group.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Kasr Alainy Faculty of Medicine- Cairo University
RECRUITINGCairo, Cairo Governorate, 11728, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketofol (ketamine and propofol mixture) and ketodex (ketamine and dexmedetomidine mixture)
What this could lead to
If one combination works better, it could point to a safer way to prevent confusion and memory problems after major cancer surgery in older adults.
What could go wrong
This is a single-center trial with 180 participants, so results may not apply to all patients. Both drug combos have side effects like low blood pressure or slow heart rate, and the study is still recruiting.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.