Brain zaps may mend heart after stroke
NCT ID NCT07482501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether repetitive transcranial magnetic stimulation (rTMS) can improve heart rate variability and quality of life in people who have had a stroke. 44 participants will receive either real or sham rTMS for 4 weeks. The goal is to see if this brain stimulation can help the heart's automatic control system work better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If it works, this could point toward a non-invasive way to improve heart function and quality of life after a stroke.
- What could go wrong
- This is a small, early-stage study with only 44 people. The treatment may not work better than a placebo, and results may not apply to all stroke survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants aged 35-80 years admitted to the Afyonkarahisar Health Sciences University Hospital Physical Medicine and Rehabilitation Unit for neurological rehabilitation after stroke * Participants with a history of stroke of at least 3 months * Neurologically and medically stable participants willing to participate regularly in the study * Participants capable of following commands Exclusion Criteria: * Serious cardiac disease, uncontrolled hypertension * Epilepsy or history of antiepileptic drug use * Intracranial metallic implants * Inner ear implants * Malignancy * Active infection * Skin infection or open wound in the intervention area * Brain lesions or medications that may alter the seizure threshold * Increased intracranial pressure * Uncontrolled migraine * Fracture or surgery on the hemiplegic side within the last 6 months * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Afyonkarahisar Health Science University
RECRUITINGAfyonkarahisar, 0300, Turkey (Türkiye)
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