Sleep disorder

This phase 3 trial tests whether a once-daily pill called orforglipron can improve sleep apnea in 600 adults with moderate-to-severe sleep apnea who are also obese or overweight. Participants are split into two groups: those who cannot or will not use a CPAP machine, and those wh…

This trial tests whether combining an online form of Acceptance and Commitment Therapy with a noninvasive brain stimulation technique can improve sleep quality in adolescents with depression and sleep problems. About 160 teens aged 11 to 19 are randomly assigned to receive the co…

This trial tests whether giving dexmedetomidine, a sedative, at night can help older adults sleep and reduce the risk of delirium after cardiac surgery. Participants are 60 or older and scheduled for heart surgery with a planned ICU stay. Half receive the drug, half receive a pla…

This trial tests an experimental oral drug, TAK-861, in people with narcolepsy type 1, a condition that causes severe daytime sleepiness and sudden muscle weakness (cataplexy). Researchers will compare TAK-861 against a placebo to see if it improves alertness and reduces cataplex…

This trial tests whether a low-sodium form of oxybate, called XYWAV, can reduce daytime sleepiness and improve daily function in adults aged 18 to 75 with idiopathic hypersomnia or narcolepsy. Participants take the oral solution at night, with doses adjusted to their needs, and r…

This large Phase 3 trial tested a once-weekly injection called retatrutide in over 2,300 adults with obesity or overweight who do not have type 2 diabetes. The study also looked at how the drug affects knee osteoarthritis and obstructive sleep apnea. Participants received either …

This study follows over 14,000 adults with sleep apnea who are prescribed positive airway pressure (PAP) therapy. It investigates whether using telemonitoring—where the device sends usage data to their doctor remotely—helps people use the therapy more consistently and effectively…

This phase 2 trial is testing whether two investigational drugs, AD109 and AD504, taken as a pill at bedtime, can reduce the number of breathing pauses in people with obstructive sleep apnea. The study compares these drugs against atomoxetine (an existing medication) and a placeb…

This study compares two different mandibular advancement devices—oral appliances that hold the jaw forward during sleep—to see which works better for people with mild-to-moderate obstructive sleep apnea. Participants will wear each device for three months, with a two-week break i…

This trial tests whether different intensities of breathing exercises (inspiratory muscle training) can improve diaphragm function, thinking, sleep, and mood in young adults aged 18-25 who have low muscle mass. Participants will be randomly assigned to high-intensity, moderate-in…

This study tests whether adding the sleep medication suvorexant to standard buprenorphine treatment can improve sleep and medication adherence in people with opioid use disorder who have recently used fentanyl. Participants first stay in a residential setting for five days to sta…

This study tests whether clarithromycin, an antibiotic, can reduce excessive daytime sleepiness in people with narcolepsy or idiopathic hypersomnia. Participants receive either clarithromycin or a placebo for 14 days. Researchers will measure changes in sleepiness, brain activity…

This trial tests whether a program using a consumer wearable device—which tracks oxygen levels during sleep—along with personalized weekly reports can help adults with obstructive sleep apnea use their positive airway pressure (PAP) therapy more consistently. Participants who are…

This study tested whether a physical activity program delivered by mail and website could improve the health of nearly 50,000 older women already in the Women's Health Initiative. The program included aerobic, balance, strength, and flexibility exercises, and encouraged reducing …

This Phase 3 trial tests retatrutide, a once-weekly injection, in 1000 adults with type 2 diabetes who are overweight or obese. The study also looks at a subset of participants with obstructive sleep apnea. Over 89 weeks, researchers will measure weight loss, changes in sleep apn…

This trial tests whether a drug called IHL-42X can reduce breathing pauses during sleep in people with obstructive sleep apnea who cannot tolerate or do not use a CPAP machine. The study has two parts: first, a short dose-finding phase to pick the best dose, then a longer phase c…

This trial tests a device called the aura6000 that stimulates a nerve in the neck to keep the airway open during sleep. It is for adults with moderate to severe obstructive sleep apnea who cannot or will not use a CPAP machine. Participants are randomly assigned to have the devic…

This study looks at whether the shape of a person's face influences how Botox injections change bite force in people who grind their teeth (bruxism). Participants with different facial structures receive Botox into the jaw muscle, and bite force is measured before and after treat…

This trial investigates whether structured exercise—either aerobic cycling or resistance training—can improve health-related biomarkers in women with breast cancer undergoing neoadjuvant therapy (chemotherapy or endocrine therapy before surgery). The main focus is on changes in K…

This study tested whether adding a telerehabilitation program (using a mobile app, video calls, and online coaching) to standard CPAP therapy helps obese adults with severe sleep apnea. 180 participants were followed for 6 months to see if the program improved daytime sleepiness,…

This completed study tested a remote, self-guided lifestyle program for 696 veterans with obesity and obstructive sleep apnea. Participants watched videos, completed handouts, and tracked their eating and activity, with optional coaching. The goal was to see if this low-cost appr…

This study tested the Inspire system, a device that stimulates a nerve in the neck to keep the airway open during sleep. It involved 44 adults in Singapore with moderate-to-severe obstructive sleep apnea who could not use CPAP. The main goal was to confirm the device works proper…

This study tested whether taking a melatonin supplement (3 mg each night for 6 months) could improve sleep, thinking skills, and blood sugar control in 70 adolescents with type 1 diabetes. Half received melatonin and half received a placebo. The researchers measured changes in bl…

This study looked at whether a diabetes drug called empagliflozin, combined with a breathing machine (CPAP), can improve sleep and heart function in 70 adults with both heart failure and obstructive sleep apnea. Participants were randomly assigned to take empagliflozin or not, an…

This study involved 155 adults with narcolepsy who were already taking a high-sodium oxybate medication. They switched to Xywav, a low-sodium version, to see if their blood pressure would improve. The goal was to provide doctors and patients with useful information about the impa…

This study tested whether a 3-year physical activity program could help prevent colon cancer from coming back in 889 patients who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. Participants were randomly assigned to either the exercise program plus…

This completed trial tested whether a low-level laser device (Alesis OSA-1) can reduce breathing pauses in adults with obstructive sleep apnea. 35 participants received six 12-minute light treatments over three weeks. Researchers measured apnea events before and after treatment, …

This completed study tested whether painting metal roofs with a special heat-reflecting coating can lower indoor temperatures and improve health in Niue, a Pacific island nation facing record heat. Researchers enrolled 288 adults living in single-story homes with metal roofs. The…

This study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (a type of irregular heartbeat) in people who also have obstructive sleep apnea. Twenty-five adults with both conditions were enrolled. Half used CPAP while the other half were o…

This study looked at 19 people with sleep apnea and mild high blood pressure. It compared a drug called bosentan to the standard CPAP machine to see if the drug could lower blood pressure just as well. The goal was to find a simpler way to manage heart risks in sleep apnea patien…

This study looks at the long-term safety and effectiveness of pitolisant in adults with idiopathic hypersomnia, a condition causing excessive daytime sleepiness. Participants had already completed a previous study. The goal is to see if pitolisant remains safe and helps control s…

This study tested whether acetazolamide, a cheap and well-tolerated water pill, can reduce sleep apnea severity and lower blood pressure in young adults (18–50 years old) who cannot or will not use a CPAP mask. 54 participants received either the drug or a placebo for two weeks e…

This study tested whether a special oral appliance called myTAP, combined with a mouth shield and deep dental cleaning, can reduce gum disease in people who snore and breathe through their mouth. 43 adults with mild to moderate gum disease completed the 12-week trial. The device …

This study tested a personalized treatment plan called VitalCare for people with obstructive sleep apnea who were starting CPAP therapy. The plan included remote monitoring and tailored follow-up to help patients use their CPAP machine more regularly. Researchers enrolled 113 par…

This study tested whether personalized sleep or nutrition advice could help night shift workers sleep better and improve their health. 57 rotating or night shift workers wore smart devices, did alertness tests, and gave blood samples. Researchers compared those who got tailored a…

Researchers test whether checking infants with Down syndrome for obstructive sleep apnea every six months, starting at six months old, helps their brain development by age three. The trial compares a group that gets regular sleep studies to a group that receives standard care. Ab…

Researchers are testing a new face mask, the Smart Mask V1 System, that uses built-in light sensors to measure blood oxygen (SpO2) and pulse rate. The study enrolls healthy adults aged 18 to 65 who wear the mask while breathing air with gradually lower oxygen levels in a special …

This study tests a smart mask that uses AI to detect sleep stages and breathing-related arousals in adults with sleep apnea. About 150 participants will wear the mask during an overnight sleep study, and its results will be compared to standard lab tests. If accurate, the mask co…

This pilot study explores whether three different home sleep apnea testing devices—NightOwl, SleepImage, and Nox T3—are practical and user-friendly for adults with type 2 diabetes. Participants will wear each device at home for three nights and answer questionnaires about their e…

Researchers test whether adding ketamine to propofol improves sedation for drug-induced sleep endoscopy in adults with obstructive sleep apnea. The procedure lets doctors see where the airway collapses during sleep. Thirty adults receive either propofol alone or propofol plus ket…

This study compares two techniques for evaluating upper airway collapse in people with obstructive sleep apnea: the standard office-based Müller's maneuver and drug-induced sleep endoscopy (DISE), which is performed under light sedation. The goal is to see whether DISE provides m…

This study tests whether a wearable home sleep apnea device called WatchPAT200 can accurately detect central sleep apnea in people who take narcotic medications. Participants wear the device during an overnight lab sleep study, and results are compared to the standard in-lab test…

This study evaluates whether a smartwatch and smartphone can accurately screen for obstructive sleep apnea (OSA). Adults suspected of having OSA will wear a smartwatch and smartphone while undergoing standard overnight sleep monitoring in a hospital. The results from the devices …

This study explores whether a three-dimensional electronic pulse diagnostic device can accurately identify Traditional Chinese Medicine (TCM) syndromes in people with sleep disorders. Participants undergo pulse measurements and symptom assessments, and the device's results are co…

This study compares a new mass spectrometry technique to the standard radioimmunoassay for measuring orexin-A levels in cerebrospinal fluid. Orexin-A is a key brain chemical that is low in people with type 1 narcolepsy. The study involves 117 people with excessive daytime sleepin…

This study tested a new, low-cost device called Apne-Scan to see if it can accurately detect sleep apnoea compared to standard home tests. Forty adults referred to a sleep clinic wore the Apne-Scan mask alongside their usual test overnight. The goal was to see if the simpler, che…

This study looked at whether monitoring oxygen levels at home for 14 nights gives a more accurate diagnosis of obstructive sleep apnea than the standard single-night test in a hospital. Researchers enrolled 130 adults with suspected sleep apnea. They compared results from home mo…

This study tested a wearable device called SUNRISE to see if it can accurately screen for obstructive sleep apnea in people with diabetes or chronic lung disease. Researchers compared its results to standard sleep testing in 37 adults. The goal is to make sleep apnea screening ea…

This study tested whether a special algorithm in a pacemaker can accurately diagnose sleep apnea in people with heart problems. Researchers compared the pacemaker's readings to a standard overnight sleep test in 66 participants. They also looked for a link between sleep apnea sev…

This study tested a new device called the BRUXENSE occlusal splint to see if it can help diagnose sleep bruxism (teeth grinding). Seven adults with bruxism tried wearing the splint for 10 nights. The goal was to see if they could use it comfortably and if it collected enough data…

This study looked at whether a home sleep apnea test can accurately detect obstructive sleep apnea in children aged 5-12 who have already had their tonsils and adenoids removed. 62 children completed both a home test and an overnight in-lab sleep study. The goal was to see how we…

This study tested whether a smartphone app called Apneal can accurately diagnose sleep apnea. 491 adults wore the app on their chest during an overnight sleep test, and the app's results were compared to the standard hospital sleep test. The goal is to see if the app can reliably…

This study tests whether a 12-week lifestyle program—combining personalized nutrition advice, regular psychological support, and a walking routine—can improve sleep quality and body composition in overweight or obese women aged 60 and older. Participants will be assessed at the s…

This study tested whether giving extra health coaching to new parents—especially fathers—could help prevent rapid weight gain in babies and reduce obesity risk. Researchers enrolled 657 parents from Massachusetts General Hospital and randomly assigned them to either receive coach…

This study tested a program to help children aged 6-11 maintain a healthy weight and feel good. Over 1,300 kids from 24 Danish schools took part. The program included changes at school and in the community to encourage healthy eating, more physical activity, better sleep, and les…

This study tested whether giving melatonin, a natural sleep hormone, could prevent delirium (sudden confusion) in elderly patients after major non-cardiac surgery. Researchers enrolled 88 patients aged 65 and older across multiple hospitals. The goal was to see if a larger trial …

This study tested a device called Cereset Research that plays tones in response to a person's brainwaves, aiming to reduce stress and improve sleep. 94 stressed healthcare workers used the device for several sessions and were followed for a year. The goal was to see if the device…

Researchers are testing whether an online exercise and self-massage program can lower jaw pain and improve jaw movement in adults with bruxism, the habit of grinding or clenching teeth. Participants complete eight sessions over four weeks, either exercising live with a physical t…

Researchers compare two six-week stress-management programs for female hospital nurses and midwives: heart rate variability biofeedback and eurythmy therapy. Participants are assigned at random to one program. Before and after, questionnaires and heart rate measurements track cha…

Researchers are testing whether the 4-7-8 breathing technique can reduce anxiety, ease symptom burden, and improve sleep quality in people receiving chemotherapy. The trial enrolls 64 adults undergoing their third treatment cycle, splitting them into a group that practices the br…

This study tests the MedCline Sleep System, a device placed on the bed to keep people sleeping on their side. It aims to reduce breathing pauses and snoring in adults with mild obstructive sleep apnea. Researchers will measure changes in apnea and oxygen levels during sleep. The …

Researchers want to know if using a temperature-controlled mattress pad changes sleep quality and deep sleep. The study includes people who already own a Chili Sleep System and an Oura Ring. For two out of four weeks, participants stop using the pad while wearing the ring and ans…

This study tested two non-drug methods—reflexology (foot massage) and sleep hygiene education—to improve sleep and comfort in 60 adults on hemodialysis. Both approaches helped, but reflexology was more effective. The results suggest a simple, drug-free option for better rest in d…

This study tests whether an 8-week forest therapy program—combining walking, resistance band exercises, and sensory activities like aromatherapy—can improve muscle strength and well-being in older women with sarcopenia. Thirty-six women aged 55 and older will participate in 16 se…

Researchers are testing whether short, repeated sessions of mild low oxygen (mild intermittent hypoxia) can strengthen upper airway muscles and improve sleep apnea treatment. Adults with newly diagnosed obstructive sleep apnea and prehypertension or stage 1 hypertension, includin…

This study tested a new combination pill called AD109 for obstructive sleep apnea (OSA) in 646 adults who could not tolerate CPAP machines. The pill aims to reduce breathing pauses during sleep by targeting brain chemicals. Results will show if it improves the apnea-hypopnea inde…

This study tested whether providing overnight infant care and parenting support helps new mothers with substance use disorder living in residential treatment programs. 41 mothers participated, and researchers measured how many enrolled, completed the program, and gave feedback. T…

Many people on long-term hemodialysis struggle with persistent pain at night and poor sleep, which lowers their quality of life. Researchers are testing a nurse-led Benson's relaxation program to see whether it reduces night pain intensity and improves sleep quality. The study en…

Researchers are testing whether cognitive behavioral therapy for insomnia (CBT-I) can improve blood sugar control in older Chinese adults with type 2 diabetes and insomnia. The trial compares CBT-I to usual care in 214 participants aged 60 and older. They will measure changes in …

Researchers are testing whether cognitive behavioral therapy for insomnia (CBT-I) can help returning veterans who drink heavily. The trial enrolls veterans deployed after September 11, 2001, who have insomnia and at least one heavy drinking episode in the past month. Participants…

Researchers at the University of Sfax are testing whether the timing of exercise changes its benefits for sleep and well-being. They enroll 102 sedentary university students aged 18 to 25 and assign them to three weekly 50-minute sessions, two weekend 75-minute sessions, or a con…

Researchers are testing whether a 10-session mechanical massage program can improve sleep quality, lower stress hormones, and affect immune function in people who report high stress and poor sleep. The study enrolls 32 adults who score high on stress and insomnia questionnaires a…

Researchers at Ataturk University are testing whether watching nature videos through virtual reality glasses can improve sleep quality and mental well-being in people with multiple sclerosis. The trial enrolls 42 adults aged 18 to 80 who have MS and are not in an attack. One grou…

Many people with obstructive sleep apnea struggle to use their CPAP machine every night. This trial compares three ways to support them: weekly phone calls from the sleep center, a printed list of frequently asked questions, or the usual care from equipment renters and sleep spec…

This study tested a combination of platelet-rich plasma (PRP) from the patient's own blood and hyaluronic acid injected into the jaw joint. Twenty-two adults with painful clicking and limited mouth opening received the treatment. Researchers used a jaw tracking device to measure …

This study looked at whether therapeutic touch—a gentle, non-invasive technique—can help people aged 65 to 85 who are in the hospital sleep better and feel less anxious. Researchers compared a group that received therapeutic touch to a control group. The goal was to see if this s…

This study tests a phone-based sleep therapy for people who have insomnia and drink alcohol in ways that could harm their health. The therapy adapts standard insomnia treatment to also address alcohol-related thoughts and behaviors. Researchers will first refine the approach with…

This trial tests whether adding mini-doses of dexmedetomidine and esketamine to standard pain relief can improve sleep quality after surgery in people at high risk of obstructive sleep apnea. Participants receive either the drug combo or a placebo through a patient-controlled pai…

This trial tests whether ozone autohemotherapy, a procedure where a person's blood is mixed with ozone and put back into their body, can improve sleep in people who have insomnia after an ischemic stroke. Researchers will measure sleep quality and look at blood markers of inflamm…

This trial tests whether listening to music for 20 minutes can improve sleep quality and reduce risk perception in pregnant women hospitalized due to the threat of premature birth. Researchers will measure sleep using the Richard Campbell Sleep Quality Scale and risk perception w…

This phase 2 trial tests whether pitolisant, a wake-promoting drug, can reduce excessive daytime sleepiness in adults aged 18 to 65 with myotonic dystrophy type 1. Participants receive either pitolisant or a placebo for a period, and researchers measure changes in sleepiness, fat…

This study tests whether a non-electric, hand-held temple massager—used daily for 4 weeks with a special lotion and optional lavender aromatherapy—can lower stress, improve emotional wellbeing, sleep quality, and overall quality of life in women aged 35 to 65. Participants use th…

This trial tests whether zolpidem, a common sleep medication, can improve sleep quality and reduce painkiller use in adults recovering from total knee replacement. Half of the participants take zolpidem 10 mg each night for two weeks after leaving the hospital, while the other ha…

This trial tests whether wearing compression garments at night affects sleep in young elite soccer players. Eighteen players will wear full compression leggings, compression calf sleeves, or non-compressive placebo garments for seven nights each, in random order, while their slee…

This study tested two sleep medications (suvorexant and zolpidem) against a placebo in 40 adults with Progressive Supranuclear Palsy (PSP). The goal was to see if targeting the brain's wake-promoting system could improve sleep quality and daytime well-being. Each person tried all…

This trial tests whether coaching older adults in healthy habits or sleep habits can improve their recovery after hip or knee replacement surgery. Participants receive four hour-long sessions with a therapist, focusing either on general healthy habits like physical activity and n…

This trial tests whether wearing a grounding patch at night improves sleep quality in cancer patients who have insomnia while in the hospital. The patch is a hydrogel sticker on the forehead, connected by a cord to a true earth connection, which may lower the body's electrical vo…

This trial tests whether a nurse-led program of sleep hygiene education and progressive muscle relaxation can improve sleep quality in obese pregnant women. Researchers will enroll 100 women in their third trimester with a BMI of 30 or higher and sleep problems. Half will receive…

This study is testing whether an 8-week mindfulness program can help hospital staff and older adults sleep better and feel less depressed. Researchers will measure changes in sleep quality, depressive symptoms, and well-being using questionnaires and overnight sleep tests. The go…

This study tests a smartphone app called BELL-001 that plays personalized sounds in sync with your breathing to help you relax and fall asleep. 114 adults with insomnia will use the app or a sham version nightly for 4 weeks. Researchers will measure changes in sleep quality and d…

This study tested whether a dental mouthpiece (mandibular advancement device) can reduce frequent nighttime urination in adults with obstructive sleep apnea. Eleven participants who woke up to pee at least twice a night used the device and tracked their bathroom visits. The goal …

This study tests whether a smartphone-based mindfulness program is practical and liked by teens and young adults (ages 15-39) with sickle cell disease who have chronic pain or sleep problems. Participants use a guided meditation app for about 8 weeks. The goal is to see if people…

This trial tests whether progressive muscle relaxation, kinesio taping, or both can reduce premenstrual syndrome symptoms like stress, depression, and poor sleep in university students. Participants are randomly assigned to one of four groups: relaxation exercises, taping, both, …

This trial tests whether sleeping with a traditional Chinese medicine herbal sachet can ease insomnia and improve sleep quality in adults aged 60 and older. Participants will place the sachet near their head each night for eight weeks, with some receiving a placebo sachet for com…

This study looked at whether a sleep medication called suvorexant can improve sleep and reduce stress in people recovering from opioid addiction. About 138 participants on medications like methadone or buprenorphine were given either suvorexant or a placebo for 8 weeks. The goal …

This trial tests whether a structured program combining psychoeducation, breathing exercises, and relaxation techniques can reduce post-traumatic stress symptoms and improve sleep quality in adults who survived the February 2023 earthquakes in Türkiye. Ninety participants living …

This trial tests whether a traditional Chinese medicine aromatic sachet, placed beside the pillow each night, can improve sleep quality in women aged 45 to 59 experiencing poor sleep during the menopausal transition. One hundred twenty-two women in Macao will use either the herba…

This study tested whether taking hydrocortisone (a cortisol-like hormone), melatonin, or both could reduce jet lag symptoms after long eastward flights. Fifty-seven healthy adults aged 18-65 who flew across 6-8 time zones took the pills for 4 days after arrival and reported their…

This trial tests whether a daily sleep gummy can improve sleep quality and quantity in adults aged 20-50 who have self-reported sleep issues. Participants take one gummy before bed for 7 days while wearing a Fitbit tracker to measure sleep patterns. The study compares sleep metri…

This trial tests whether a topical roll-on and diffuser blend can improve sleep quality and duration in adults who have had sleep issues for the past month. Over six weeks, 40 participants will use the diffuser blend at night for three weeks, then switch to the roll-on applied to…

This trial tests whether a 20-minute foot massage, given daily for three days after open heart surgery, can reduce pain, improve sleep quality, and boost mood. Adults undergoing coronary artery bypass grafting who report significant pain after surgery are randomly assigned to rec…

This trial tests whether an educational program delivered via telemedicine can improve sleep quality, sleep habits, and physical activity in medical students with poor sleep. Participants are randomly assigned to receive the same sleep education either remotely or in person. Slee…

This study is testing whether special drug-free patches can help relieve acute back, shoulder, or other muscle pain and improve sleep. The patches use a gentle vibration technology instead of medication. 150 adults aged 18-64 will wear either an active patch or a sham (fake) patc…

This study tests whether practicing MediYoga—a gentle form of yoga—through a smartphone app can improve sleep quality, lower blood pressure, and boost quality of life in people aged 65 and older who have hypertension. Participants will be randomly assigned to do 20 or 40 minutes …

This trial tests whether progressive muscle relaxation and deep breathing exercises can help people with COPD feel less tired and sleep better. About 90 participants will be split into three groups: one practicing muscle relaxation, one doing deep breathing exercises, and a contr…

This trial tests whether different combinations of cannabinoids—THC, CBN, CBG, CBD, and melatonin—taken as gummies can improve sleep quality in adults aged 21 to 55 who report poor sleep. Participants will be randomly assigned to receive one of several active gummy formulas or a …

This study tested whether a Persian-language internet program called Omid, based on cognitive behavioral therapy, can improve sleep in adults with insomnia. Thirty participants were randomly assigned to use the program or receive usual care. The program includes weekly online les…

This pilot study explores whether cancer patients are willing to complete a quick self-screening for insomnia during clinic visits, and whether a video-based cognitive behavioral therapy (CBT-I) could help them sleep better. The study involves adults with breast, colorectal, lung…

This trial tests whether a group-based psychological treatment for insomnia, adapted for people with depression, anxiety, or PTSD, can improve sleep and reduce psychiatric symptoms. Participants receive either the adjusted CBT-i program or usual care. The study measures changes i…

This trial tests whether TECAR therapy, a non-invasive device that delivers energy to painful areas, can reduce pain in people with fibromyalgia. About 46 adults with fibromyalgia will receive either real or sham TECAR sessions twice a week for three weeks. Researchers will measu…

This study tests whether chair-supported yoga can improve sleep quality and reduce pain in people aged 65 and older who live in nursing homes. Participants will be randomly assigned to either attend chair yoga sessions twice a week for 8 weeks or receive routine care only. The tr…

This trial tests whether therapeutic touch or foot reflexology can improve sleep quality and ease menopausal symptoms in postmenopausal women who lived through the 2023 Kahramanmaraş earthquakes. About 155 women will be randomly assigned to receive one of the two therapies or to …

This study explores whether sleep problems in children with ADHD are linked to being overly sensitive to everyday sensations, like touch or sound. It tests a bedtime routine called 'Power Down' that uses gentle massage and calming cues to help children relax before sleep. The stu…

This trial tests whether a 6-week virtual Tai Chi and Qigong program can improve sleep quality in adults aged 50 and older. Participants take three 50-minute online classes per week, with some starting immediately and others waiting six weeks. Researchers measure sleep quality an…

This study explores whether a single-session sleep training program can improve sleep and reduce symptoms of borderline personality disorder (BPD) in teenagers. Teens aged 13-18 with BPD symptoms will receive a brief intervention based on the TSC-Youth protocol, which teaches hea…

This study asks whether Su Jok therapy, a complementary technique that gently stimulates specific points on the hands, can reduce shortness of breath and improve sleep in adults with asthma. Participants will be randomly assigned to receive either Su Jok therapy alongside their u…

This study tests whether a mobile app can help people with gastroesophageal reflux disease (GERD) reduce symptom recurrence and improve sleep quality and quality of life. Participants with confirmed GERD will be randomly assigned to either use the app—which provides education, li…

This trial tests whether a structured nurse-led program can improve sleep quality in adults with chronic heart failure. Participants will receive education on healthy sleep habits and cognitive-behavioral techniques, alongside their usual care. The study measures changes in sleep…

This trial tests whether taking magnesium can reduce stress in people with fibromyalgia, a condition marked by widespread pain and fatigue. Participants will be randomly assigned to receive magnesium or a placebo, and researchers will measure stress levels along with pain, sleep,…

This trial tests whether daily omega-3 fish oil supplements can improve sleep, mood, and behavior in children who have sleep problems and symptoms of ADHD, autism, or both. The study takes a symptom-focused approach, aiming to identify which specific difficulties—like emotional u…

This Phase 1 trial evaluates the safety and tolerability of MMH-450, an experimental tablet that dissolves under the tongue, in 18 healthy adults aged 18 to 45 with normal sleep habits. Participants take the drug daily for 7 days while researchers monitor for side effects. The st…

This trial tests whether a set of EMF protection devices—including pads, chips, and bands—can improve sleep quality and energy levels in adults aged 30-60 who have trouble sleeping. Participants use all devices daily for about four weeks while tracking sleep with a wearable ring …

This study explores whether an AI-powered chatbot can deliver personalized sleep coaching to Black/African American adults aged 18-25 who have poor sleep and at least one cardiometabolic risk factor. The chatbot uses principles of cognitive-behavioral therapy for insomnia (CBT-I)…

This trial compares Botox injections with ibuprofen pills to see which better eases jaw muscle pain and improves quality of life in people with sleep bruxism (teeth grinding). Forty adults with jaw pain are randomly assigned to receive either Botox injections into the masseter an…

This study tests whether online cognitive-behavioral therapy (CBT) for insomnia, combined with CBT for pain, can reduce headaches and improve sleep in adolescents aged 11-17 who have both migraine and insomnia. Participants receive internet-delivered programs focusing on sleep hy…

This pilot study tests whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep in Chinese adults with chronic insomnia. CBT-I is a non-drug approach that combines techniques like stimulus control, sleep restriction, and relaxation therapy. The study measures c…

This study tested a 16-week sensory-friendly physical activity program for autistic children aged 7-12 in special education schools. The program included predictable routines and calming cool-downs to help with sleep. Researchers measured sleep quality using wrist monitors and pa…

This trial investigates whether daily exposure to a bluish-white light (at least 300-500 lux for two hours) can improve sleep efficiency, reduce depression, and calm agitation in people with mild to moderate Alzheimer's or related dementias. Participants are assigned to one of th…

This trial tests whether a mobile health app called mTranS-C can improve sleep quality in adolescents who are at risk for depression and anxiety but do not yet have a psychiatric diagnosis. The app delivers a behavioral sleep intervention designed to address insomnia and delayed …

This trial tests whether the sleep medication suvorexant can improve restorative sleep and reduce insomnia in older adults recovering from elective surgery. Participants aged 50 to 90 who have a history of insomnia will receive either suvorexant or a placebo during their hospital…

This study tests whether a medication called RE03 (dexmedetomidine), already used in intensive care, can improve sleep in people with PTSD who have trouble sleeping or nightmares. Twenty-four adults with PTSD will receive either the drug or a placebo in random order, and their sl…

This study compares two non-drug approaches to improve sleep in adults with poor sleep quality. One group uses aromatherapy and pink noise, while another practices muscle relaxation and breathing exercises. All participants also receive sleep hygiene education. The goal is to see…

This pilot study tests whether listening to specially designed audio patterns (Brain Dynamic Audio Stimulation) for 30 minutes daily can improve sleep in healthcare workers with insomnia. Fifteen participants will use the audio for two weeks, and researchers will measure changes …

This study tests whether adding cervical and sacroiliac joint mobilization to a Pilates exercise program reduces pain, stress, and jaw clenching in adults with bruxism (teeth grinding). Thirty-eight participants will either do Pilates alone or Pilates plus manual therapy twice a …

This study tests whether personalized advice on sleep timing, light exposure, meal times, and physical activity can improve sleep quality in adults aged 65 and older who have poor sleep. Participants are randomly assigned to receive either general sleep advice or a customized pla…

This study tests whether taking magnesium L-threonate for six weeks improves sleep quality, mental focus during fatigue, and muscle function in healthy adults aged 18 to 45. Participants receive either the supplement or a placebo, and researchers measure sleep scores, reaction ti…

This study tests whether a daily supplement called NPQ Plus can improve skin health, antioxidant status, fatigue, and well-being in healthy adults with minor skin concerns like dryness or itchiness. The supplement contains polyphenols, NMN, PQQ, CoQ10, and minerals. Participants …

This study tests a specially adapted form of cognitive behavioral therapy for insomnia (CBT-i) in people with bipolar disorder who have sleep problems. The therapy includes sleep scheduling, light exposure, and relaxation techniques. Researchers want to see if it improves sleep q…

This study tests two digital sleep interventions designed to help teenagers aged 12-14 improve their sleep regularity and mental health. Participants wear a Garmin device and use a smartphone app that provides personalized feedback on their sleep patterns. The goal is to see if t…

This study tests whether the dietary supplement Fitoavia can help people recover from jet lag faster. Adults who have traveled across at least four time zones will take either Fitoavia or a placebo for several days. Researchers will track symptoms like sleep disruption and thinki…

This study tests whether an online guide based on Acceptance and Commitment Therapy (ACT) can help college students with insomnia. Participants will either receive the online ACT program or be placed on a waitlist. The program includes sleep education, mindfulness skills, and beh…

This study tests a smartphone app called Sleepio that teaches teens with insomnia how to sleep better using cognitive behavioral therapy. The participants are 14- to 18-year-olds who have recently been hospitalized for suicidal thoughts or attempts. The goal is to see if improvin…

This completed study tested two ways to improve sleep in children aged 1 to 7 years: a mobile app (Storybook) that guides caregivers through calming bedtime activities, and face-to-face sessions teaching sleep hygiene and routines. Sixty families in Ecuador took part over one mon…

This trial tests whether a very low dose of two drugs—dexmedetomidine and esketamine—given at night can improve sleep quality in older adults (65-89 years) undergoing knee or hip replacement. Poor sleep after surgery is common and linked to worse recovery. The study compares the …

This study tested a behavioral sleep program for 16 depressed teenagers who slept less than 7 hours on school nights or had irregular sleep schedules. The program included one session with a provider and used smartphone tools to help teens create a plan for longer and more regula…

This study tested whether a plant-based melatonin supplement (phytomelatonin) from tomatoes can improve sleep quality better than synthetic melatonin or a placebo. 244 adults with poor sleep took one capsule nightly for 28 days. Sleep was tracked with a wearable ring and question…

This study tests an oral drug called SDX (serdexmethylphenidate) to see if it safely reduces excessive daytime sleepiness in adults with idiopathic hypersomnia, a condition where people feel extremely sleepy during the day despite getting enough sleep at night. Participants will …

This study tests two behavioral therapies—imagery rehearsal therapy (IRT) and targeted dream control (TDC)—to reduce nightmares in adults with narcolepsy. Participants attend therapy sessions, keep a daily sleep log, and complete questionnaires. Some Chicago-area participants als…

This study looked at whether extra family support helps children with Down syndrome and obstructive sleep apnea use their positive airway pressure (PAP) machine more regularly. 27 children aged 6-18 were split into two groups: one received standard care, the other got a family-in…

This phase 3 study tests whether YZJ-1139 tablets help adults with insomnia fall asleep faster and sleep more efficiently. Participants receive either 20 mg, 40 mg, or a placebo daily for two weeks. Sleep is measured using both sleep diaries and overnight lab tests.

This trial investigates whether jaw exercises (Rocabado programme) work better when guided by a physiotherapist through online video sessions versus doing them at home with written instructions alone. Adults aged 18-60 with jaw-joint pain and teeth grinding are randomly assigned …

This clinical trial tests whether a new drug called YZJ-1139 can help people with insomnia sleep better than the commonly used medication zolpidem. Adults aged 18 to 64 with insomnia disorder take either YZJ-1139 or zolpidem daily for 28 days. Researchers measure sleep quality us…

This study tested whether Benson relaxation exercises can improve sleep quality in cancer patients. 72 adults with cancer were randomly assigned to do relaxation exercises or receive a sleep hygiene booklet. The goal was to see if this simple, non-drug method could help with slee…

This study tested whether adding telehealth coaching to a digital cognitive behavioral therapy program helps people with insomnia complete the treatment. 700 adults with insomnia were enrolled. The goal was to see if coaching improves adherence and reduces disparities in who bene…

This study tested two simple treatments for snoring in people with mild sleep apnea: low-level laser therapy applied to the mouth and soft palate, and oropharyngeal exercises (like tongue and throat workouts). 180 adults aged 40-55 took part. The goal was to see which approach re…

This study tested whether daily gummies containing L-theanine and lion's mane mushroom extract could reduce stress, anxiety, and improve sleep in university students. 67 students aged 18-25 took either the gummies or no supplement for 8 weeks. The goal was to see if this natural …

This study tested whether a mild electrical current applied to the head (called transcranial electrostimulation, or TES) can help control pain after major sleep apnea surgery. 45 patients received TES along with standard care. The goal was to see if TES reduces pain and the need …

This study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…

This study tests whether cognitive behavioural therapy for insomnia (CBT-I) can improve sleep and ADHD symptoms in adolescents aged 12 to 18 who have both ADHD and insomnia. Participants receive either CBT-I plus usual care or usual care alone. The goal is to see if addressing in…

This study tested whether teaching good sleep habits could help people with painful diabetic nerve damage sleep better and feel better overall. Twenty-four patients were split into two groups: one received a booklet and face-to-face sleep training from a nurse, while the other co…

This Phase 2 trial tested AXS-12 (reboxetine) in 21 adults with narcolepsy and cataplexy. Participants received either the drug or a placebo for three weeks, then switched. The goal was to see if AXS-12 could reduce weekly cataplexy attacks and improve excessive daytime sleepines…

This study tested a 12-week remotely-supervised rehabilitation program for 60 men aged 25-65 with moderate to severe obstructive sleep apnea. The goal was to see if the program could improve breathing pauses during sleep, daytime sleepiness, and overall quality of life. Participa…

This study tested whether an AI-guided writing program could help teens feel less anxious, depressed, or stressed. Over three days, 486 Chinese adolescents wrote about negative experiences, with some receiving personalized AI feedback. The goal was to see if this simple, digital …

This study tested a new medicine called ALKS 2680 in 92 adults with narcolepsy type 1, a condition that causes severe daytime sleepiness and sudden muscle weakness (cataplexy). Participants stopped their usual narcolepsy medications and received either ALKS 2680 or a placebo for …

This study tested a technique called cryo-auriculotherapy, where a device freezes specific spots on the ear, to see if it helps people with chronic insomnia. Sixty-five adults with moderate to severe insomnia received either real or sham (fake) treatments over three months. The m…

This trial tests whether applying platelet-rich fibrin (PRF) — a wound dressing made from a patient's own blood — to the roof of the mouth after gum graft surgery improves pain, sleep, and overall quality of life compared to standard dressings. About 78 adults needing gum surgery…

This study tested whether a herbal supplement called Redormin 500 (made from valerian and hop extracts) can help people with occasional sleep problems think more clearly during the day and feel better overall. Forty healthy adults with mild sleep issues took either the supplement…

This study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …

This study tested whether eye masks and calming audiobooks could improve sleep for children aged 6-15 in the pediatric intensive care unit. Forty-two children were randomly assigned to use these tools or receive standard care. Researchers measured sleep quality and vital signs to…

This study tested a six-session behavioral sleep program, called Apnea and Insomnia Relief (AIR), in 118 Gulf War veterans with Gulf War Illness. The program combined sleep education, motivation for using a breathing machine, and insomnia therapy, all done via telehealth. Researc…

This study tests whether repeated acupressure can help reduce agitation, pain, and sleep disturbances in intensive care unit (ICU) patients who are on mechanical ventilators. Participants receive either real acupressure or a light touch (sham) twice daily for four days. Researche…

This study looked at whether a swaddle blanket with a gentle abdominal band can reduce acid reflux, breathing pauses, heart rate drops, and low oxygen levels in premature infants. About 50 babies in the NICU were observed to see if the blanket helped. The goal was to find a simpl…

This study tested whether a drug called acetazolamide can improve sleep-disordered breathing in women traveling to high altitude (3600 m). 303 healthy adults participated in a randomized, placebo-controlled trial. The main goal was to see if the drug reduced drops in oxygen level…

This study looked at whether taking gac fruit oil capsules for 30 days could help adults aged 40 to 65 who have trouble sleeping. The 50 participants took four capsules daily and were tested on sleep quality, vision, mood, and brain scans before and after. The goal was to see if …

This study looked at whether surgery to fix a blocked nose can improve snoring and sleep apnea in adults. Thirty people with nasal obstruction and sleep apnea had surgery. The main goal was to see if their breathing pauses during sleep (measured by the apnea-hypopnea index) got b…

This study tested whether wearing special light glasses for 30 minutes each morning could help breast cancer patients feel less tired, sleep better, and think more clearly during treatment. The trial included 260 women with early-stage breast cancer, plus a healthy comparison gro…

This study looked at whether a 4-week behavioral sleep program could improve both sleep and thinking in 62 older adults with chronic insomnia. Participants learned sleep habits, relaxation, and adjusted their bedtimes. The researchers measured sleep changes and daily thinking per…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were adults aged 18-75 with military-related PTSD and insomnia. The study …

This completed trial tested whether combining online acceptance and commitment therapy (ACT) with customized sound therapy helps people with tinnitus and insomnia. 164 adults were split into two groups: one received both therapies, the other only sound therapy. The goal was to se…

This study tested a six-session behavioral therapy that teaches people with narcolepsy type 1 how to become aware during dreams (lucid dreaming) and control frightening images. Ninety-eight adults took part, with half receiving the therapy and half getting standard care. The goal…

This study tested an experimental drug called AXS-12 (reboxetine) in 90 people with narcolepsy who experience cataplexy (sudden muscle weakness) and excessive daytime sleepiness. Participants took either the drug or a placebo twice daily for several weeks. The main goal was to se…

This study followed 90 Canadian adults with insomnia who were prescribed daridorexant. Researchers tracked changes in quality of life, work productivity, and sleep symptoms over three months using questionnaires. The goal was to see how the medication helps people in everyday lif…

This small study tested a dietary supplement called NatureU Sweet Dream, which contains GABA and Lactium, against a standard melatonin product in 17 adults with mild to moderate sleep problems. Participants wore a sleep tracker to measure deep sleep duration and percentage. No si…

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This early-stage study tested a new insomnia drug called HEC83518 in 74 healthy Chinese adults aged 18 to 45. The main goal was to check safety and side effects after a single dose. Researchers also measured how the drug moves through the body. This is a first step to see if the …

This early-stage trial tested a new drug called HEC83518 in 57 healthy Chinese adults to see if it is safe and how the body processes it. Participants took the drug or a placebo daily for 15 days. The study focused on side effects and drug levels in the blood, not on whether it i…

This small study tested whether combining digital cognitive behavioral therapy for insomnia (CBT-I) with sessions in a sauna blanket is feasible for adults with insomnia. Ten participants used an online CBT-I program and a sauna blanket at home for 9 weeks. The goal was to see if…

This study tested a 10-week digital detox program for 160 teens aged 10-19 who use smartphones at least 3 hours daily. The program included weekly sessions on reducing screen use, setting goals, and improving sleep habits. Researchers measured changes in screen addiction, sleep q…

This study looked at whether exercising in the morning or evening helps control blood sugar better in pregnant women with gestational diabetes or glucose intolerance. 39 women walked or stepped for 30 minutes either after breakfast or after dinner. The researchers measured blood …

This study tested a phone-based health coaching program to help people with sleep apnea use their positive airway pressure (PAP) device more often. 27 adults who were not using their device enough took part. The coaching aimed to improve device use and reduce daytime sleepiness.

This study tested the DOZE app, a digital self-management program designed to improve sleep in young adults aged 18-25 with chronic pain and insomnia. Forty participants used the app and a sleep diary for 10 weeks. The goal was to see if the app is easy to use and helps with pain…

This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. About 220 adults aged 18 to 64 with back pain for at least 3 months and sleep problems took either melatonin or a placebo for several weeks. …

This study tested whether partial-body cryotherapy (standing in a very cold chamber for 2-3 minutes) could help reduce fatigue in people with multiple sclerosis during a rehabilitation stay. 43 participants received either real cryotherapy at -120°C or a sham version at -30°C ove…

This study looked at whether eating microgreens can improve sleep patterns in athletes. Twenty active athletes without heart disease took part. Researchers measured sleep stages, total sleep time, and muscle soreness to see if microgreens help with recovery and rest.

This study tested whether pillows filled with herbs can improve sleep and quality of life. Thirty healthy adults used the pillows for two weeks while wearing a sleep monitor and filling out questionnaires. The goal was to see if a simple, natural approach could help people sleep …

This study looked at whether a short sleep therapy program (BBTI) can improve sleep and help people stay in treatment for substance use disorders. About 83 adults living in a residential recovery program took part. They wore sleep trackers, completed surveys, and did sleep diarie…

This study looked at whether aromatherapy (lavender oil foot massage) and reflexology (pressing specific points on the feet) could reduce pain and improve sleep in 90 children with cerebral palsy, aged 6 to 12. Children were split into three groups: aromatherapy, reflexology, or …

This study tested an online program to help cancer patients with insomnia. It included 348 adults with cancer who had trouble sleeping. The program used cognitive-behavioral techniques and aimed to see who might need extra help from a professional.

This study tested a version of cognitive behavioral therapy for insomnia, specially adapted for night shift workers. 60 nurses who work night shifts and have insomnia took part. The goal was to see if the therapy is practical and helps improve sleep and reduce fatigue.

This study tested a mobile app called PCYCARE in 120 first-time pregnant women in their third trimester. The app provides educational modules and guided relaxation sessions over 21 days. Researchers measured changes in anxiety, sleep quality, and childbirth preparedness compared …

This study tested two programs to help older adults stop taking sleeping pills like lorazepam or zolpidem. One program focused on placebo effects—the power of believing a treatment works—while the other did not. Both included cognitive behavioral therapy and special pill packagin…

This study tested an online program called SLEEPexpert that teaches behavioral techniques to improve sleep in people with mental disorders. 68 psychiatric inpatients with insomnia used the program alongside their usual treatment. The goal was to see if it helps reduce insomnia an…

This study tested whether wearing an eye-ear sleep band, which blocks light and noise, could improve sleep quality in 100 adults admitted to a coronary care unit with acute coronary syndrome. Each patient spent one night with the band and one night with standard care, in random o…

This study looked at whether drinking tart cherry juice can improve sleep in older adults with insomnia. Twenty people aged 65 and older drank cherry juice and a placebo for 4 weeks each while wearing a sleep tracker. Researchers checked if the study was easy to follow and measur…

This study tested whether a three-week aerobic exercise program could reduce PTSD symptoms and improve sleep in 82 adults who survived the February 2023 earthquake in Turkey. Participants were randomly assigned to either supervised exercise sessions or a control group. Researcher…

This study tested whether using virtual reality (VR) glasses for 30 minutes each evening could improve sleep quality, reduce anxiety, and stabilize vital signs in intensive care patients with COPD. Fifty patients were split into two groups: one received VR sessions for a week, th…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …

This study tested whether the drug acetazolamide can improve sleep-disordered breathing in 39 adults with chronic pain who use opioids. Participants took either the drug or a placebo for one week each. The goal was to see if the pill could reduce sleep apnea events as an alternat…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study tested whether a 12-week nurse-led program could help people on hemodialysis feel better and function better. 220 patients were split into two groups: one got the extra program during dialysis sessions, and the other got standard care. The program included light exerci…

This completed Phase 2 trial tested whether Neurexan, a homeopathic tablet, can improve sleep and reduce stress in 81 people with short-term insomnia. Participants took Neurexan or a placebo for 14 days. Sleep efficiency was measured using brain activity and other body signals, w…

This phase 2 study tested an experimental drug called ALKS 2680 in 93 adults with narcolepsy type 2, a condition causing severe daytime sleepiness. Participants took either the drug or a placebo daily to see if it safely improved their ability to stay awake. The trial is now comp…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep, quality of life, and reduce hopelessness in older adults living in a nursing home. Fifty people aged 65 and older took part, with half receiving acupressure three…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested whether installing special LED lights that mimic sunlight in hospital rooms could help treat depression and improve sleep. Fifteen adults with major depression participated. The goal was to see if the lights were comfortable and if they could reduce depression s…

This study tested whether virtual reality relaxation or binaural beat stimulation can improve sleep and reduce discomfort in 140 adults who had mechanical heart valve replacement. Many patients struggle with sleep due to the sound of the new valve. Participants were randomly assi…

This study followed 71 adults with narcolepsy who started taking LUMRYZ, a medication for excessive daytime sleepiness. Over 4 months, participants filled out questionnaires about their symptoms, how they felt about the drug, and their quality of life. The goal was to see if LUMR…

This study tested a special sleep program for teenagers with ADHD who also have sleep problems. The program combines cognitive behavioral therapy with sleep tips and planning skills. Researchers wanted to see if better sleep could also improve ADHD symptoms and daily life. The st…

This study tested whether adding a virtual coach (phone support) helps veterans with insomnia use a digital cognitive behavioral therapy program for sleep. 244 veterans were randomly assigned to either the digital program with coaching or with minimal contact. The goal was to see…

This study tested whether two types of gentle exercise—stretching or traditional pregnancy exercises—could improve sleep quality in pregnant women during their third trimester. Sixty women with sleep troubles took part in guided sessions twice a week for three weeks. The goal was…

This study tested a new automatic setting (Auto-EPAP) on a ventilator to see if it could better manage airway blockages during sleep compared to the standard manual setting. It involved 23 adults with conditions like sleep apnea, COPD, or obesity-related breathing problems who al…

This study tested a drug called solriamfetol in 59 adults with obstructive sleep apnea who also had trouble thinking clearly and felt very sleepy during the day. The goal was to see if the drug could improve cognitive function, like attention and processing speed. Participants to…

This study tested whether inhaling lemongrass (as a vapor or from an inhaler) could reduce nicotine dependence and improve health markers in 200 adult smokers aged 18–30. Participants used lemongrass products or nothing (control) and provided blood samples and questionnaires. The…

This study tested whether custom mouthguards (splints) designed using a 3D jaw-tracking device called MODJAW work better than standard mouthguards for people with teeth grinding (bruxism) or jaw pain. 40 adults with mild-to-moderate symptoms wore either a personalized or standard…

This study tested whether an Apple Watch paired with a special app and weekly health coaching could help dementia caregivers improve their sleep and mood. Twenty-one caregivers wore the watch to track their activity and sleep, and received personalized feedback and motivational c…

This study tested an app called EMPOWER-ED that provides education and tools to help veterans reduce or stop taking benzodiazepines (like Xanax or Ativan). Long-term use of these drugs can lead to dependence and other risks. The study enrolled 170 veterans who had been taking ben…

This study tested whether a digital program called Sleepio, which provides cognitive behavioural therapy for insomnia, could be used by people with mild cognitive impairment or mild dementia. Thirty participants were enrolled to see if the program was acceptable and easy to use. …

This early study tested whether the drug acetazolamide can reduce breathing pauses during REM sleep in people with obstructive sleep apnea who cannot use a CPAP machine. Eleven participants took either the drug or a placebo for a few nights. Researchers measured breathing events …

This pilot study tested a program called Sleep-SMART for veterans aged 60 and older who have both mild cognitive impairment (MCI) and insomnia. The program combines standard insomnia therapy with memory-support strategies to help participants learn and stick with the treatment. R…

This small pilot study tested whether cannabis oil (with different ratios of CBD to THC) could help with insomnia in people who also have major depression. Fourteen adults took either a high-CBD oil, a low-CBD oil, or a placebo for a short time. The main goal was to see if a larg…

This study tested a special sleep program for 40 people who recently lost their spouse or long-term partner. The program used online sessions to teach better sleep habits and was compared to just giving information. The goal was to see if it could improve sleep and reduce inflamm…

This study tested whether taking rosemary and daylily extracts can improve sleep in adults over 50 who have trouble falling asleep. Ten participants took either a low or high dose of the herbal supplement or a placebo for eight weeks. The goal was to see if the supplements could …

This study tested a mobile app called SleepFix that provides digital behavioral therapy for insomnia in 128 older adults aged 50+ who also had mild memory concerns. Participants either used the app or received online sleep health education. The goal was to see if the app could re…

This study tested a smartphone app that teaches older adults (60+) simple behavioral tricks to fall asleep faster and stay asleep longer. 270 participants used either the app or received online sleep tips. The goal was to see if the app could reduce insomnia symptoms more effecti…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep in elderly people living in care homes. 75 residents took part, with half receiving 12 acupressure sessions over four weeks. The results showed that those who rece…

This study tested whether an 8-week sleep coaching program delivered through a smartphone app is practical and acceptable for cancer survivors and their bedroom partners. Forty participants were enrolled to see if they would stick with the program and find it helpful. The goal wa…

This study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…

This study tested a culturally adapted internet-based cognitive behavioral therapy (iCBT) program for Arabic-speaking refugee and migrant youth aged 15–29 with mild to moderate mental health problems like depression, anxiety, and insomnia. 125 participants were randomly assigned …

This study tested a special educational program based on motivational interviewing to help people with sleep apnea use their CPAP machine more regularly. 100 adults newly prescribed CPAP took part. The program aimed to improve adherence, motivation, quality of life, and daytime s…

This study tested a mobile app called SleepFix that helps people with chronic low back pain and insomnia improve their sleep. Over 100 adults used either the app or received sleep education for 3 weeks. The goal was to see if better sleep could reduce how much pain interferes wit…

This study looked at 558 adults with mild to moderate sleep apnea who also don't get enough sleep. Researchers compared two programs: one focused on improving use of a PAP machine, and another on sleep education. The goal was to see which works better for reducing daytime sleepin…

This study tested whether a safe sleep aid could help people with obstructive sleep apnea use their CPAP machine more each night. Many patients struggle to keep the mask on all night, often because they wake up easily. The trial gave a medication to raise the sleepers' arousal th…

This study tested whether a jaw-widening surgery (surgically assisted maxillary expansion) could improve quality of life in 9 adults with obstructive sleep apnea. Participants completed sleep questionnaires before surgery and again 3 months and 1 year after. The goal was to see i…

This study tested whether a simple mandala coloring activity could reduce anxiety, fatigue, and improve sleep quality in people aged 65 and older living in nursing homes. Over 8 weeks, participants colored mandala patterns for 1-2 hours each week. The study measured changes using…

This study tested whether doing special tongue and throat exercises for 12 weeks after surgery helps people with moderate-to-severe sleep apnea breathe better at night. 51 adults were split into two groups: one did the exercises after surgery, the other had surgery only. The exer…

This study tested whether a 4-week program of diaphragmatic breathing exercises before bed can reduce sleep bruxism (teeth grinding) in 100 adults. Participants learned deep breathing techniques and practiced them nightly, while a control group listened to neutral music. The goal…

This study tested a program to improve sleep and daytime activity in frail adults aged 65 and older with insomnia. Seven participants tried a 24-hour approach to build healthier sleep-wake habits. The goal was to see if the program was practical and well-liked, and to measure cha…

This study looked at whether a non-invasive brain training method called neurofeedback can help veterans who have had a mild traumatic brain injury and still suffer from chronic headaches, trouble sleeping, and attention problems. 87 veterans were randomly assigned to receive neu…

This study tested whether adding the sleep medication eszopiclone (Lunesta) to brief behavioral therapy improves sleep quality and CPAP use in veterans with PTSD and complex insomnia. Fifty-three veterans who had trouble sticking with CPAP therapy for sleep apnea took part. The g…

This study tested whether a new drug called tasipimidine can help people with insomnia fall asleep faster and stay asleep longer. 190 adults with chronic insomnia took either the drug or a placebo for 3 nights in a sleep clinic, with some continuing for 4 more weeks at home. Rese…

This study looked at ways to help people who had a stroke use a CPAP machine for sleep apnea during their rehab stay. Sleep apnea is common after stroke and can slow recovery. The researchers tested different approaches to improve how often patients used the CPAP machine over thr…

This study tested a new once-nightly medication called FT218 for people with narcolepsy who experience excessive daytime sleepiness and sudden muscle weakness (cataplexy). It included 184 participants, some already on a twice-nightly medication and some new to treatment. The goal…

This study tested a steroid nasal spray (mometasone furoate) in 130 children aged 3-12 who snore and have sleep-disordered breathing. The goal was to see if the spray could relieve symptoms enough to avoid surgery to remove tonsils or adenoids. Children used the spray daily for 6…

This study tested a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) in 70 people with brain tumors who also had trouble sleeping. The therapy involved six weekly group sessions delivered online. The main goal was to see if the approach was practical …

This study tested different doses of melatonin to see which one best improves sleep quality in autistic children aged 3 to 12 who have trouble sleeping. Researchers measured things like how long it takes to fall asleep, total sleep time, and number of night awakenings using sleep…

This study tested whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and reduce pain in women with fibromyalgia. 131 women with both conditions received either CBT-I or sleep hygiene education. Researchers measured sleep quality, pain sensitivity, and bra…

This study tests whether shining low-level laser or LED light on specific acupoints on the hand can help people relax and improve sleep and anxiety. Researchers will measure heart rate and energy levels in 60 healthy volunteers before and after light therapy. The goal is to see i…

This study tested two online programs—cognitive behavioral therapy (CBT) and mindfulness—to help adults cope with the distress caused by tinnitus (ringing in the ears). 67 participants were randomly assigned to one of the two treatments or a waiting list. The goal was to see if t…

This study looked at whether adding special breathing muscle training to running programs helps 10-13-year-old male football players improve their agility, endurance, and lung function. 75 boys who had played football for at least two years took part. The training was tailored to…

This study tested whether a remote patient monitoring platform (MonitAir) could help people with obstructive sleep apnea use their CPAP machine more consistently. 200 adults starting CPAP therapy were randomly assigned to receive standard coaching or enhanced monitoring with the …

This small study tested whether the sleep medication lemborexant (Dayvigo) can help people with moderate-to-severe obstructive sleep apnea (OSA) who have a low arousal threshold—meaning they wake up easily during sleep. Ten untreated adults each took the drug or a placebo on two …

This study tested a new 8-session psychotherapy called ChronoS in 67 adults with mood disorders (bipolar or depression) and chronic insomnia. The therapy focuses on sleep-wake awareness and habits. Researchers measured changes in insomnia severity using a standard questionnaire. …

This study tested three types of medicinal cannabis oil (with different levels of THC and CBD) against a placebo in 91 cancer patients. The goal was to see which oil, if any, helps with pain, nausea, anxiety, and sleep problems. Each patient tried multiple oils and a placebo in a…

This study tested whether daily omega-3 supplements (fish oil) can help reduce stress, anxiety, depression, and improve memory and sleep in 64 Saudi adults who reported high stress. Participants took either omega-3 or a placebo for three months. Those taking omega-3 reported lowe…

This study tested a new mindfulness-based therapy called ACTCOM-I against standard cognitive behavioral therapy (CBT) for chronic insomnia in 31 adults. The new therapy focuses on acceptance and self-compassion to improve sleep. Researchers measured changes in insomnia severity a…

This study looks at whether a short sleep education program can improve sleep habits and quality in health sciences students. About 100 students will attend four weekly 40-minute classes covering bedtime routines, caffeine limits, and stress management. Researchers will measure s…

Researchers are looking at whether the FIB-4 index, a blood-based score that estimates liver fibrosis risk, tracks with the severity of obstructive sleep apnea (OSA) and low oxygen levels during sleep. They will review records from 373 adults who had full-night sleep studies, gro…

This study looks at how common sleep breathing problems are in children with cerebral palsy across the UK, and how often they use breathing support like CPAP machines. Researchers will track new cases over a year and explore what helps or hinders access to care. The goal is to im…

Researchers are studying whether daily step counts and other smartwatch measurements can predict which cancer patients will be readmitted to the hospital after discharge. Adults who have just left an oncology ward wear a Huawei smartwatch for 30 days to track steps, heart rate, a…

Researchers want to know if exercising in the morning or evening changes physical performance and blood markers in healthy young male soccer players. Eight participants complete the same jump and shuttle-run tests twice, once in the morning and once in the evening, with a four-da…

This study tested whether bright light in the afternoon, alone or with morning light, can shift teens' internal body clocks earlier. 84 adolescents aged 18-20 followed a stable sleep schedule and then lived in a lab for a week. Researchers measured melatonin levels to track clock…

This study aims to translate and validate a French version of the Sleep Regularity Questionnaire (SRQ), a tool that measures how consistent a person's sleep schedule is. Researchers will enroll 50 adults with chronic insomnia or circadian rhythm disorders, who will fill out the q…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages, including children as young as 8, to track patterns of these conditions over time.…

Researchers at the University of Pavia are studying whether long-term exposure to urban air pollution and work-related stress affects biological aging. The study compares 151 adult workers in Pavia, Italy: outdoor workers such as police officers, taxi drivers and dustmen, and ind…

Idiopathic hypersomnia causes severe daytime sleepiness that differs from narcolepsy, yet researchers do not know what drives it. This study uses 64-electrode EEG to look for local slow waves, a sign of sleep-like activity in parts of an otherwise awake brain, while participants …

This study looks at how changing sleep patterns affects eating behavior and self-control in 120 children who are overweight or at risk for obesity. Researchers will monitor sleep, brain activity, and real-world eating to understand the link between sleep and weight gain. The goal…

This study follows 450 patients who recently had cardiac surgery to see how often sleep disordered breathing occurs and whether it changes over time. Researchers screen participants with the ApnoeLink Air device at the start of cardiac rehabilitation, again after 3 weeks, and at …

This trial asks whether the 'first-night effect'—poorer sleep in an unfamiliar place—impairs next-day strength and muscular endurance, and whether men and women respond differently. Thirty-two resistance-trained adults (16 women, 16 men) will sleep 8 hours at home and 8 hours in …

This study looked at how sleep quality and beliefs about sleep affect the risk of relapse in people recovering from alcohol dependence. Researchers followed 198 adults as they left inpatient rehab and returned home, measuring sleep with questionnaires and activity monitors. The g…

This study looks at whether vitamin D levels differ among adults with and without obstructive sleep apnea (OSA). Researchers will compare blood vitamin D measurements in four groups: healthy controls, simple snorers, OSA patients without other health conditions, and OSA patients …

This study looks at whether adults with bruxism—teeth grinding or clenching—have different blood levels of vitamin D, calcium, and related hormones compared to those without the condition. Researchers will compare these biochemical markers between the two groups using existing la…

This study investigates whether sleep duration and timing influence nicotine dependence, cravings, and withdrawal differently in Black and white smokers. Researchers will compare daily smokers and non-smokers, monitoring sleep with an Actiwatch and having participants undergo a s…

This study looks at whether following simple sleep hygiene tips—like keeping a consistent schedule and a cool, quiet bedroom—can help orthopedic surgeons recover strength and mental sharpness after performing surgery. Researchers will measure handgrip strength, sleep quality, str…

This study looked at whether people with binge eating disorder have a disrupted body clock. Researchers compared 43 adults with and without the condition, measuring melatonin levels and activity patterns. The goal was to understand how the circadian system might be involved, whic…

This study investigates whether different types of sleep apnea—a condition where breathing repeatedly stops during sleep—are linked to future heart problems or death in people who have recently had a heart attack. Researchers will use a home sleep test called polygraphy to measur…

This study investigates how the brain learns to recognize patterns across experiences and how sleep helps solidify those memories. Healthy adults aged 18-35 will perform learning tasks while their brain activity is monitored using MRI and EEG. The researchers will also use sound …

This trial tests whether a mobile exercise app can deliver the same benefits as supervised training. Healthy university students will be randomly assigned to use the 7-Minute Workout® app, follow a supervised high-intensity interval training program, or receive no intervention fo…

This study investigates whether partial sleep deprivation, compared with normal sleep, changes metabolic and cognitive functions related to food intake, hunger, and memory. Healthy young men aged 20-28 will undergo both sleep conditions in a controlled setting, with blood samples…

This study evaluates whether prismaLINE PAP devices accurately count breathing events (apneas and hypopneas) compared to the gold-standard polysomnography (PSG) in people with sleep apnea. Participants will use a full face mask during a titration night, where the device briefly l…

This study investigates the link between the physical structure of the upper airway and its tendency to collapse during sleep, which is a key factor in obstructive sleep apnea. Researchers will measure airway collapsibility using a special pressure device, and assess anatomy via …

This study looks at how melatonin from lotions and bubble baths enters the body compared to traditional oral tablets. Researchers will measure melatonin levels in saliva after use to see how quickly it is absorbed and how long it stays in the system. The trial involves healthy un…

This study looks at what influences sleep quality in patients recovering in the intensive care unit after open-heart surgery. Researchers will measure pain, fatigue, and environmental stressors to see which factors most affect sleep. The goal is to find ways to improve sleep and …

This completed pilot study in Yomitan Village, Okinawa tested three simple, low-cost approaches to reduce stress and encourage healthy habits in 45 adults with overweight or pre-metabolic syndrome. Participants were randomly assigned to receive health leaflets, wear functional cl…

This study looks at a nerve in the neck called the ansa cervicalis, which controls muscles that help keep the airway open. Researchers will measure the nerve's size and shape in 50 adults having neck surgery for head and neck cancer. They will also test how stimulating the nerve …

This study looks at the link between depression and hypersomnia—a condition causing excessive sleepiness. Researchers will monitor brain activity during sleep and measure reward function in 45 adults with idiopathic hypersomnia or hypersomnia linked to a psychiatric disorder. The…

This study investigates whether individual physiological traits that cause obstructive sleep apnea (OSA) can predict how well CPAP therapy works. Researchers will follow adults newly diagnosed with OSA who are starting CPAP, measuring factors like arousal threshold and breathing …

This study investigates whether playing sounds associated with learned images during sleep can improve memory by reactivating the context (like location or time) in which the images were learned. Healthy adults will learn image-scene associations, then nap while related sounds ar…

This study tests whether a very short sleep survey, called the Sleep Vital Sign, can help primary care doctors recognize sleep disorders like sleep apnea, insomnia, and restless leg syndrome. About 1,260 adults visiting their Kaiser Permanente doctor will fill out the survey, whi…

This observational study looks at whether people with bruxism (teeth grinding or clenching) have different levels of certain substances in their saliva, such as cortisol and immune markers, compared to healthy individuals. It also examines if these biological markers are linked t…

This study investigates whether closing the mouth during sleep improves or worsens breathing in people with obstructive sleep apnea. Researchers use drug-induced sleep endoscopy to measure airflow through the nose and mouth separately, then briefly close the mouth every other bre…

This study looks at how well university athletes sense their own body signals (like heartbeat or tension), their stress levels, anxiety, and sleep quality, and how these relate to physical tests like grip strength, jump height, flexibility, and balance. Researchers also check if …

This study looks at how sleep and body clock disruptions impact the brain's reward and impulse control systems in teenagers. Researchers will monitor sleep, brain activity, and decision-making in 100 healthy high school students. The goal is to understand why poor sleep may incre…

This study tests whether spending less time in bed for four weeks can deepen sleep and boost memory in adults aged 65-85 who have poor sleep and are at risk for Alzheimer's. Researchers will measure brain activity, memory, and blood markers. The goal is to see if a simple behavio…

This study looks at how good or poor sleep quality influences quality of life, depression, and fatigue in people with multiple sclerosis. Researchers will survey about 121 adults with MS to measure their sleep patterns and link them to these health outcomes. The goal is to better…

This study examines whether ticagrelor, a heart medication, changes how the body absorbs and processes YZJ-1139, an experimental insomnia treatment. Healthy volunteers aged 18 to 45 will take YZJ-1139 alone and then with ticagrelor to compare drug levels and safety. The goal is t…

This study looks at whether a 90-minute afternoon nap, a moderate dose of caffeine, and a short recovery routine (stretching plus a snack) can improve evening athletic performance. Sixty elite university athletes (30 men, 30 women) will try different combinations of these strateg…

This study examines whether a new insomnia drug, YZJ-1139, can be safely taken with the antidepressant escitalopram. Healthy adults aged 18 to 45 will receive both drugs and be monitored for side effects, drug levels in the blood, and changes in eye movements, balance, and thinki…

This study examines how the sleep aid YZJ-1139 behaves in people with severe kidney impairment compared to those with normal kidney function. Sixteen adults will receive a single 20 mg dose, and researchers will measure drug levels in the blood and urine, as well as any side effe…

This study looked at how children with cerebral palsy, their parents, and healthcare professionals experience sleep disordered breathing and its management. Researchers interviewed 24 participants to understand the challenges and what helps or hinders treatment. The goal was to g…

This study looked at jaw disorders and teeth grinding in 76 elite basketball referees compared to healthy people. Referees face high stress and often hold a whistle between their teeth, which may strain the jaw. Researchers used ultrasound to measure jaw muscle thickness and foun…

This study looked at how two types of exercise—high-intensity interval training (HIIT) and continuous moderate exercise—affect sleep and inflammation in 52 older adults with HIV. Participants exercised three times a week for 16 weeks. Researchers measured sleep quality through su…

This study looks at how getting too little sleep and not putting weight on one leg affects muscle strength and balance. Healthy adults who exercise regularly will walk on one leg and sleep either 5 or 9 hours for three days. Researchers will measure muscle size, strength, and how…

This study investigates why people develop obstructive sleep apnea (OSA) and whether the underlying cause affects how they respond to different treatments. Researchers will test three approaches—CPAP, a sleep medication (eszopiclone), and supplemental oxygen—in adults with OSA. T…

This study looks at how not getting enough sleep and being awake at odd hours affects your thinking, blood chemistry, and the helpful bacteria in your gut. Researchers gave 55 healthy adults a prebiotic supplement or a placebo to see if it could help counter the negative effects.…

This study looked at how sleep quality improves when people with obstructive sleep apnea start using a CPAP machine. Researchers used a special headband to track deep sleep at home for 7 nights before and 9 nights after starting treatment. The goal was to see how quickly sleep ge…

Sleep problems affect up to 90% of people with alcohol dependence and often lead to relapse. This study tests whether a short questionnaire called the Short Sleep Index (SSI) can reliably measure sleep quality compared to a longer, standard sleep questionnaire. Researchers will a…

This study tested whether eating 28 grams of pistachios (about 40 nuts) one hour before bedtime could help regulate the body's internal clock in 28 overweight young adults. Researchers measured melatonin levels, antioxidant activity, and sleep-wake patterns. The goal was to see i…

This study surveys anesthesiologists to explore whether feelings of being a fraud (impostor phenomenon) are linked to everyday memory and attention lapses. Participants complete online questionnaires about impostor feelings, cognitive failures, anxiety, depression, sleep quality,…

This study compared 80 women with and without fibromyalgia to measure muscle strength, muscle thickness, vitamin D levels, and sleep quality. Researchers used advanced tools like isokinetic dynamometers and ultrasound to find differences between the groups. The goal was to better…

This completed study looked at 1,740 newly married couples to see if the bacteria in their mouth, eyes, and gut are linked to sleep problems, vision issues, and mood. Participants provided samples and completed surveys about sleep, anxiety, depression, and dry eye symptoms. The g…

This study explored sleep disorders in 37 adults with non-small cell lung cancer. Participants filled out questionnaires about their sleep, symptoms, mood, and quality of life. The goal was to create a guide to help doctors diagnose and treat sleep issues in this group, ultimatel…

This early study tested whether a small electrode placed near the nerve that controls tongue movement could help people with obstructive sleep apnea. Fourteen adults who already needed surgery took part. The main goal was to see if the approach was safe and could make the tongue …

This study tested whether stimulating certain nerves or muscles in the throat can improve breathing in people with obstructive sleep apnea. Researchers placed temporary electrodes and measured airflow during sleep in 35 adults. The goal was to see if this approach is feasible and…

This early study tested whether a small electrode placed near the tongue nerve could be safely used in people with obstructive sleep apnea. 14 adults who could not use CPAP took part. The goal was simply to see if the nerve could be reached and stimulated, not yet to treat the co…

This study looked at whether being physically active can lessen the negative effects of poor sleep on the heart, thinking, and well-being. Researchers compared active and sedentary adults before and after three nights of reduced sleep. The goal is to understand if regular aerobic…

This study looked at the medical records of one person from a sleep clinic to see if their breathing problems were due to a condition called dysanapsis (where airways are smaller than normal) rather than true asthma. The goal was to better understand why some people with sleep ap…

This study tested a medical device called CAVA that uses electrodes on the face to record eye movements during sleep. Nine volunteers wore the device along with standard sleep monitoring equipment in a sleep lab. The goal was to see if CAVA could accurately classify sleep stages …

This study tested a special bassinet designed to keep mother and baby together safely after birth. 160 new mothers used either the new Couplet Care bassinet or a standard one. Researchers surveyed mothers about sleep, breastfeeding, and satisfaction, and reviewed medical charts. …

This study looked at how sleeping at high altitude (3600 m) affects breathing in healthy women, and whether the phase of their menstrual cycle makes a difference. 91 women spent two nights at altitude while their oxygen levels and breathing patterns were measured. The goal was to…

This study looked at 103 adults with narcolepsy or obstructive sleep apnea to see if anxiety, social, or work factors affect their ability to stay awake during a standard test. Participants filled out an anxiety questionnaire before the test. The goal is to better understand why …

This study looked at how using a tablet in the evening affects young children's sleep and thinking skills. Researchers compared kids who used a tablet before bed with those who had no screen time. They measured changes in sleep timing, melatonin levels, and executive function. Th…

This study examined whether older adults with disrupted sleep or irregular daily rhythms show early brain changes linked to Alzheimer's disease. Researchers used wrist-worn activity monitors and brain MRI scans in 47 people over 65 without major memory problems. The goal was to s…

This completed study looked at whether practicing Orgasmic Meditation (OM) is associated with better sleep quality. 41 experienced OM practitioners tracked their sleep using a phone app for 30 nights. The study aimed to see if more OM sessions or experiencing orgasm during practi…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study looked at whether a 15-minute meditation practice called Shoonya meditation can help people stay sharp after a night without sleep. Researchers compared regular meditators to people who nap regularly, measuring brain activity, heart rate, and cognitive performance. The…

This study tested a new approach called DREAM, where Veterans at risk for sleep apnea could go straight to home sleep testing without an initial in-person clinic visit. Over 6,500 Veterans took part to see if this speeds up diagnosis and treatment. The goal is to make sleep apnea…

This completed study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and track changes with treatment. Researchers analyzed stored blood samples from 388 people with and without sleep apnea, and also collected new samples from pat…

This study followed 59 nurses during their first year of work to see if night shifts harm bone health. Researchers measured bone density and markers of bone turnover in night shift nurses compared to day shift nurses. The goal was to understand if shift work increases the risk of…

This study looks at how stress and insomnia are connected. Researchers used driving simulations with stressful events to measure emotional reactions and sleep patterns in 15 women with and without insomnia. The goal is to understand how stress affects sleep and vice versa, which …

This completed study looked at sleep problems in over 1,100 children and adults with specific learning disabilities (like dyslexia or dyspraxia), with or without ADHD. Participants filled out online questionnaires about their sleep habits. The goal was to find out how common diff…

This study looked at how the drug modafinil affects driving ability in 27 people with narcolepsy or hypersomnia. Participants took modafinil or a placebo for five days, then completed both simulated and real driving tests. The goal was to see if the drug improves alertness and re…

This study looked at whether a 30-minute daytime nap can help mentally tired endurance athletes feel better and think more clearly. Eleven male amateur athletes completed two sessions: one where they did mentally tiring tasks before napping, and another where they just napped. Re…

This completed study looked at how sleep apnea and other health problems like diabetes and high blood pressure affect pain after root canal treatment. 78 adults were divided into three groups: those with sleep apnea, those with diabetes or high blood pressure, and healthy people.…

This study tested whether playing short sound bursts in sync with brain slow waves during sedation with dexmedetomidine can enhance sleep-like brain activity. 18 healthy adults each experienced in-phase, anti-phase, and sham stimulation in repeated blocks. The goal was to see if …

This study looked at 48 young adults (24 with bruxism, or teeth grinding, and 24 without) to understand how jaw function, posture, muscle stiffness, pain, stress, and sleep quality are connected. Researchers used special tools to measure posture, muscle tightness, and pain levels…

This study tested whether smartphone notifications could improve mood, physical activity, and sleep in over 1,000 medical interns. Participants received daily mood, activity, or sleep notifications through a mobile app. The study measured mood scores, step counts, sleep duration,…

This study looked at whether veterans with traumatic brain injury (TBI) and insomnia can reliably measure their internal body clock at home. Thirty-one veterans wore a wrist device for a week and collected saliva samples to track melatonin levels. The goal was to see if these hom…

This study looked at 198 adults with non-metastatic gastrointestinal cancer to see if taking chemotherapy as a pill (oral) or through a vein (IV) affects sleep quality and depression. Researchers measured sleep and mood before treatment, at 45 days, and at 90 days using standard …

This study tested a mobile app designed to help teenagers with asthma learn about healthy sleep habits. 120 teens aged 14-17 with asthma used the app or were in a comparison group. Researchers measured changes in sleep knowledge, confidence, and daytime sleepiness to see if the a…

This study looked at whether a wearable device (Xiaomi Mi Band 8) can accurately detect sleep-related breathing disorders. About 300 adults wore the band during a standard overnight sleep test. Researchers compared the band's sleep-stage data with the hospital test to see if wear…

This study followed 520 French adults with central or mixed sleep apnea to see how a treatment called adaptive servo-ventilation (ASV) improved their sleep quality. Participants used a breathing device that adjusts pressure in real time. The goal was to measure changes in sleep q…

This study looked at how sleep health impacts recovery quality in 174 adults after hip or knee replacement surgery. Participants wore activity monitors and kept sleep diaries to track their sleep patterns. The goal was to see if poor sleep leads to worse recovery, helping doctors…

This study looked at how children ages 8 to 17 use smartphones and tablets, including social media and games, and how that relates to their mental health, sleep, and physical activity. Over 900 children and their parents used the Aura app and completed surveys for three months. T…

This study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…

This study placed 15 healthy volunteers in a natural cave with no access to time cues for 40 days. Researchers measured how their sense of time, sleep cycles, stress levels, and group coordination changed. The goal was to understand how humans adapt to extreme isolation and time …

This pilot study tested whether limiting food intake to an 8am-to-6pm window for four weeks could improve metabolic health and appetite regulation in 16 healthy adults. Participants ate freely during that window and fasted the rest of the time. The study measured changes in appet…

This study looked at 138 physical therapy students aged 18-30 to see if their eating habits, sleep quality, and stress levels are linked. Participants filled out three questionnaires about eating attitudes, sleep, and perceived stress. The goal was to understand how these factors…

This completed study enrolled 230 people with Parkinson's disease, a related sleep disorder, and healthy volunteers. Participants used a smartphone app to track their movements daily and underwent brain scans. Some also gave skin biopsies to test for a protein linked to Parkinson…

This study looked at 106 people with obesity who were scheduled for weight-loss surgery. Researchers measured how their upper airways behaved during sleep and used MRI scans to see if changes after surgery could explain why some develop obstructive sleep apnea and others do not. …

This study watched 225 people with solid tumors who got a drug called G-CSF during chemotherapy. G-CSF can cause bone pain. Researchers measured pain levels and tracked what treatments (like pain relievers or other methods) helped. They also checked quality of life, fatigue, mood…

This completed pilot study looked at whether a quick, non-invasive eye scan (OCT angiography) can detect early blood vessel changes in the retina of people with obstructive sleep apnea. Researchers compared 166 adults with and without sleep apnea. The goal was to see if retinal i…

This study looked at 150 children and adults who had their tonsils removed using one of three surgical methods: BiZact, coblation, or bipolar. Researchers measured pain after surgery, how long the operation took, when patients could eat solid food again, and how much the devices …

This study looked at whether insomnia affects pain sensitivity in people with Irritable Bowel Syndrome (IBS). Researchers measured pain thresholds using a barostat procedure in 70 participants, including IBS patients with and without insomnia, healthy volunteers, and people with …

This study tested whether a structured nutrition education program could improve nursing students' nutrition knowledge, eating habits, physical activity, and sleep quality. Forty-two students took part in multiple educational sessions. Researchers measured changes right after the…

This completed study tracked 132 children with obstructive sleep apnea who had their tonsils removed. Researchers recorded how many had breathing problems after surgery, especially those with other health issues. The goal was to create a simple flowchart to help doctors decide wh…

This study used a very powerful 7 Tesla MRI to look for tiny brain changes in 15 people with idiopathic REM sleep behavior disorder (iRBD) compared to 15 healthy volunteers. iRBD is a sleep condition that often leads to Parkinson's disease years later. The goal was to find early …

This study looked at how specific tongue muscles help keep the airway open during sleep in people with obstructive sleep apnea. Researchers used a special camera during sleep-like sedation to measure airway collapse. The goal was to understand the mechanisms behind airway obstruc…

This completed study with 40 participants explored factors that might predict obstructive sleep apnea in people with Down syndrome. Researchers used a range of assessments, including sleep studies, heart monitoring, and exercise tests, to identify early warning signs. The goal is…

This study looked at how sleep quality, when people eat, and gut bacteria are linked to obesity. Researchers tested a mobile app to help people make healthier lifestyle changes. The study included 133 adults with different body weights, including some with sleep apnea. The goal w…

This study looked at whether a nutrition and behavior change program could help reduce sleep apnea in people who are overweight or obese. About 400 adults took part, and researchers measured changes in sleep apnea risk, daytime sleepiness, and weight loss. The goal was to see if …

This completed study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Researchers used overnight oxygen tests and sleep studies to find cases. The goal was to understand if sleep apnea is linked to diabetes compl…

This study looked at 200 heart transplant patients to see if the time of day the donor heart was removed affects how well the patient does. Researchers compared hearts taken during the body's rest phase (midnight to noon) versus the active phase (noon to midnight). They tracked s…

This study followed 127 first-time mothers to see if their sleep quality, anxiety levels, and nighttime phone use before labor were linked to how long labor lasted and whether they needed extra medical help. Participants filled out questionnaires during routine checkups, and rese…

This study looked at whether working night shifts for just three nights in a row can disrupt bone health. Twenty healthy adults aged 20-40 either followed a normal sleep schedule or stayed awake at night and slept during the day. Researchers measured bone turnover markers to see …

This study looked at whether rotating shift workers can stick to a time-restricted eating plan, where they only eat during certain hours. Researchers wanted to see if this approach is practical and how it affects blood glucose levels during day and night shifts. 31 healthcare wor…

This study followed over 200 sleep apnea patients from a large European database to see how many developed heart problems, metabolic issues, cancer, or died over time. Researchers also checked whether using CPAP therapy (a common sleep apnea treatment) affected these risks. The g…

This study looked at how the timing of sleep affects what teenagers eat. Researchers wanted to understand why getting more sleep helps some teens eat less, but not others. They studied 190 healthy teens aged 14-18 to see if matching sleep to their natural body clock improves thei…

This study looked at 24 children (ages 6-17) with narcolepsy or hypersomnia to see if changes in their metabolism explain why they often gain weight and become obese. Researchers measured energy use at home and in the hospital using activity trackers. The goal was to understand t…

This study followed 2,365 adults from urban areas of Chile for 12 months to learn more about chronic pain and its effects. Researchers looked at how chronic pain relates to mental health issues like depression and anxiety, as well as work stress and daily functioning. The goal wa…

This study followed 113 adults with myotonic dystrophy (Steinert's disease) for 5 years to find out what factors lead to low breathing (hypoventilation). Researchers measured lung function, sleepiness, fatigue, and thinking skills. The goal is to better understand which patients …

This study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict declines in thinking skills and daily functioning. Participants filled out questionnaires about their symptoms and quality of life. The goal was to better understand how …

This study tested whether a short power-nap (less than 30 minutes) can help anesthesiology residents perform better after working night shifts. 44 residents took part in high-fidelity simulations to measure their technical and non-technical skills. The goal was to see if napping …

This study looked at how often sleep apnea occurs in adults with type 1 diabetes. Researchers monitored 53 participants overnight using standard sleep tests and continuous glucose monitors. The goal was to measure the link between sleep-disordered breathing and blood sugar contro…

This study tested different parts of a common insomnia treatment (CBT-I) to see which ones work best alone or together. 489 adults with chronic insomnia took part online. The goal was to find the most effective combination for future use.

This completed observational study looked at 72 men and women aged 20-50 who work rotating night and day shifts. Researchers measured blood sugar, weight, sleep patterns, and other health markers to understand how short-term circadian misalignment from shift work affects the body…

This study looked at how not getting enough sleep affects blood pressure and feelings of discrimination in 77 African American adults. Participants underwent sleep restriction and had their heart health measured during social tasks. The goal was to understand links between sleep,…

This study looked at how race-based social rejection impacts sleep and nighttime heart function. About 139 African American and Caucasian adults spent two nights in a sleep lab—one after a rejection task and one after a neutral task. Researchers measured how quickly they fell asl…

This study looked at how sleep apnea might make brain problems worse after surgery. Researchers enrolled 32 adults with moderate-to-severe sleep apnea who were scheduled for surgery. They used brain scans and memory tests before surgery, two days after, and six months later to tr…

This study looked at how to help busy doctors at VA clinics adopt better treatments for three common issues: reducing risky medications in older adults, using blood thinners more safely, and offering talk therapy for insomnia instead of sleep pills. Researchers compared two diffe…

This study tested a wearable system that records brain waves and delivers gentle ultrasound to deep brain areas during REM sleep. Fifty-two healthy adults and people with mild sleep or stress issues wore the device for two nights. The goal was to see if it safely increases REM sl…

This study looked at 28 people with both stable coronary artery disease and moderate sleep apnea. Researchers measured blood markers of oxidative stress (a type of cell damage) before and after 3 months of CPAP therapy. The goal was to see if CPAP could reduce oxidative stress, w…

This study looked at 48 adults with mood disorders and insomnia to see if a strong relationship with their therapist helped them get better results from a new type of therapy called ChronoS. The therapy combines sleep scheduling, mindfulness, and stress management. Researchers me…

This study looks at how disrupted sleep changes the way common drugs (like painkillers, stimulants, and sedatives) work in the body. Researchers will disturb the sleep of 148 healthy adults in a lab and then measure how their brains respond to these drugs, including pain relief a…

This completed study observed 563 patients who had weight-loss (bariatric) surgery and received extra oxygen during their first night in the hospital. Researchers tracked how often oxygen levels fell below 90% and what actions nurses took, like adjusting the oxygen flow or reposi…

This completed study looked at 171 people with HIV to see if insomnia makes pain worse and increases inflammation. Participants wore sleep trackers, kept sleep diaries, and underwent pain tests. The goal was to understand if poor sleep drives pain and inflammation, which could ma…

This study measured dental movements in 180 adults with sleep apnea who use an oral appliance. Researchers used 3D photographs of teeth to track changes in tooth rotation and length. The goal was to better understand how these devices affect tooth position over time.

This study looked at 172 adults with obstructive sleep apnea to compare the risk of heart attacks, strokes, and eye problems between two common treatments: a CPAP machine and a dental mouthpiece. Researchers did not give any new treatment—they simply observed patients already usi…

This study looked at how moving an oral appliance forward by just one millimeter at a time affects sleep apnea severity and symptoms like daytime sleepiness. Twenty adults with moderate or severe sleep apnea took part. Researchers measured breathing pauses during sleep and used q…

This study looked at how people with obstructive sleep apnea and their bed partners adapt to CPAP therapy, a common treatment that uses a machine to keep airways open during sleep. Researchers interviewed 24 patients and their partners to understand what helps or hinders consiste…