Narcolepsy 1
MONDO:0008062A rare disorder characterized by sudden and transient episodes of loss of muscle tone. It often follows an experience of intense emotions. It is seen in patients with narcolepsy.
Also known as: HCRT narcolepsy, narcolepsy 1, narcolepsy caused by mutation in HCRT, NRCLP1, cataplexy, narcoleptic syndrome 1
33 clinical trials for this condition and its sub-types, 5 tagged with Narcolepsy 1 itself.
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New pill aims to tame Narcolepsy's sleep attacks and sudden muscle weakness
Disease control Recruiting nowThis study tests whether HBS-301 (pitolisant) can reduce excessive daytime sleepiness and cataplexy (sudden muscle weakness) in adults with narcolepsy. Participants receive either the drug or a placebo for several weeks, followed by an open-label phase where everyone gets the dru…
Phase 3 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Could a wearable device replace hospital sleep tests for kids with cerebral palsy?
Diagnosis Recruiting nowThis study is testing whether simple wearable devices can accurately screen for sleep disorders in children with cerebral palsy. About 140 children aged 6 to 15 will wear the devices at home and then undergo a standard hospital sleep test. The goal is to see if the wearable metho…
Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Amino acid supplement tested for better sleep in brain injury
Symptom relief Recruiting nowThis study tests whether taking branched chain amino acids (BCAAs) twice a day for three weeks can improve sleep in people with traumatic brain injury. Researchers will also check if the supplement is easy to take and if participants stick with it. The study involves 300 veterans…
Sponsor: Portland VA Medical Center • Aim: Symptom relief
Last updated Sep 19, 2026 00:00 UTC
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Medical cannabis under the microscope: 1,000 patients tracked for Real-World relief
Symptom relief Recruiting nowThis study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to see how well medical cannabis work…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Sleep therapy could be key to preventing suicide in young adults
Symptom relief Recruiting nowThis study looks at whether adding sleep-focused treatments to standard psychiatric care can reduce suicide risk in young adults. About 90 college students with suicidal thoughts and sleep problems will be randomly assigned to one of three sleep interventions. Researchers will tr…
Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC
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Can a 4-Week online course tame your night terrors?
Symptom relief Recruiting nowThis study tests a 4-week online course designed to help adults who experience parasomnias—unwanted sleep events like sleep terrors, sleepwalking, and nightmares. The course teaches safety planning, relaxation, and therapy techniques. Researchers will measure whether it reduces h…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Memory tricks may help older adults finally get a good Night's sleep
Symptom relief Recruiting nowThis study tests whether a special memory support program can help people aged 50 and older remember and stick to their sleep treatment. The program uses simple memory strategies alongside standard sleep therapy. Researchers will track sleep quality, daily functioning, and life s…
Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC