Teen sleep study seeks to unlock brain secrets behind Risk-Taking
NCT ID NCT04792697
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study looks at how sleep and body clock disruptions impact the brain's reward and impulse control systems in teenagers. Researchers will monitor sleep, brain activity, and decision-making in 100 healthy high school students. The goal is to understand why poor sleep may increase the risk of substance use, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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115 people
The number who actually took part.
- Started
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May 2021
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 15 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Typically enrolled in a traditional high-school with synchronous learning (in-person or online synchronous learning, but not cyber- or home-schooling) \[school closures during the COVID-19 pandemic are an exception to this\] * Physically and psychiatrically healthy * Provision of written informed consent and assent * Additional inclusion criterion for Experimental protocol: Meets operational definition of late sleep timing (\>10:50PM habitual bedtime) Exclusion Criteria: * History of alcohol, cannabis, or illicit drug use in the past month, or greater than monthly use in the past year * Significant or unstable acute or chronic medical conditions * Frequent headaches or migraines * History of seizures * Current serious psychiatric disorder (e.g., depressive disorder, bipolar disorder, eating disorder, psychotic disorder diagnosis, alcohol use disorder or substance use disorder) that would interfere with completion of study procedures * Current syndromal sleep disorders other than insomnia and delayed sleep phase disorder * MRI contraindications (i.e., absence of metal in the body, claustrophobia) * Medications that increase sensitivity to blue light/photosensitizing medications, including psychiatric neuroleptic drugs, psoralen drugs, antiarrhythmic drugs, etc. * Changes to psychotropic medication regimen in the 2 weeks prior to enrollment, and/or major changes to medications during the study protocol * If participants have an average bedtime that is later than 3:00AM or an average wake time later than 11:00AM they may be excluded from the study * Participants should be EXCLUDED for other sleep disorders that require ongoing treatment * Participants should be EXCLUDED for other sleep disorders that cause significant distress or impairment, per DSM 5 criteria in the Sleep SCID.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Western Psychiatric Hospital
Pittsburgh, Pennsylvania, 15213, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.