Dream control: a new behavioral approach to tame narcolepsy nightmares
NCT ID NCT05709873
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests two behavioral therapies—imagery rehearsal therapy (IRT) and targeted dream control (TDC)—to reduce nightmares in adults with narcolepsy. Participants attend therapy sessions, keep a daily sleep log, and complete questionnaires. Some Chicago-area participants also undergo a daytime nap sleep study. The goal is to see if these therapies can lower nightmare frequency and severity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- imagery rehearsal therapy and targeted dream control
- What this could lead to
- If effective, these therapies could offer a drug-free way to reduce nightmare frequency and severity in people with narcolepsy.
- What could go wrong
- This is a very small early study with only 7 participants, so results may not apply to everyone. The treatments require time and commitment, and not everyone may benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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7 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Apr 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (all participants): * Diagnosis of narcolepsy * Age 18 or older * Speak English * Live in the United States * Receiving standard medical care for narcolepsy * Sleep and psychiatric medications stable for at least 3 months * Nightmare frequency of ≥3 times per week * Nightmare Disorder Index score indicates probable nightmare disorder Inclusion Criteria (Chicago area participants): * Able to attend a study appointment in Evanston, IL * Able and willing to not take wake-promoting medications on day of lab visit Exclusion Criteria: * History of a neurological disorder that might alter EEG * Currently engaged in sleep- or trauma-focused psychotherapy * Previous behavioral treatment for nightmares * Medical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatment * Untreated sleep apnea (AHI ≥ 5)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern University
Chicago, Illinois, 60611, United States
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Other studies related to the condition(s) this trial covers.
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