Northwestern University

This study tests a radiation treatment (Y90) to help grow the liver in people with liver cancer who need surgery but don't have enough healthy liver left. The goal is to make surgery possible and improve survival. About 104 participants will receive either standard or optimized Y…

This study compares two standard surgical methods for removing kidney stones: mini-PCNL (a small incision in the back) and flexible ureteroscopy with a suction tube. The goal is to see which method leaves fewer stone fragments behind. About 80 adults with kidney stones between 1 …

This study looks at how well different types of liver transplants work for people whose colorectal cancer has spread to the liver and cannot be removed by standard surgery. Researchers will compare living versus deceased donor transplants, whole versus split liver, and one-step v…

This study tests a new approach for people with a recently diagnosed aggressive brain cancer called glioblastoma. A device with 9 ultrasound emitters is implanted in the skull to temporarily open the blood-brain barrier, allowing immune-boosting drugs to reach the tumor more effe…

This study compares two surgical techniques for removing a uterine septum, a wall of tissue inside the uterus that can cause problems. Researchers want to see if using scissors without electricity is better than using an electric tool. The study will measure surgery time, costs, …

This study tests whether shining a specific red light on the legs each day before a walking workout can help people with peripheral artery disease (PAD) walk farther. PAD causes leg pain and difficulty walking due to narrowed arteries. The trial will involve 32 adults aged 50 and…

This study tests whether dupilumab, a drug already used for eczema, can reduce severe itching in people with genetic skin disorders. About 30 participants will receive the drug for up to 104 weeks. The goal is to see if itch improves and if the treatment is safe.

This study tests whether combining a type of brain stimulation (called iTBS) with computer-based attention training can improve attention and daily life for people with mild traumatic brain injury (mTBI) and/or PTSD. Researchers will enroll 200 adults aged 18–80 who have had a mi…

This study looks at whether injecting Botox into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and leaks. About 66 men aged 18-89 with these symptoms will take part. The goal is to see if the combination is s…

This study tests whether an online program that teaches positive emotion skills can improve mental well-being and slow biological aging. Researchers will measure changes in mood, purpose, and biological age markers in 80 adults aged 40-70 from the Chicago area. The program is sel…

This study looks at heart failure, a condition where the heart can't pump enough blood, causing shortness of breath and tiredness. Researchers will collect data from 1,000 adults, including heart images and blood tests, to find different types of heart failure. The goal is to hel…