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Marriage microbiome: could your Partner's bacteria affect your sleep and eyesight?

NCT ID NCT06638606

Knowledge-focused Sponsor: Reza Rastmanesh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 1,740 newly married couples to see if the bacteria in their mouth, eyes, and gut are linked to sleep problems, vision issues, and mood. Participants provided samples and completed surveys about sleep, anxiety, depression, and dry eye symptoms. The goal is to understand how these bacteria might influence health, but it does not test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal links between microbiota and sleep, vision, or mood in couples, pointing toward future interventions.
What could go wrong
This is an observational study, not a treatment trial. Results may show correlations but not cause, and findings may not apply to other groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,740 people

The number who actually took part.

Started

Jan 2024

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All volunteer participants who had been officially married during the past six months and are in a cohabiting relationship will be invited to participate in this study together with their official spouses.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sleep disorder (insomnia and hypersomnia) * Depressive/anxiety states Exclusion Criteria: * Medicines known to affect gut/oral/ocular microbiota composition * Pregnant/pregnancy * Divorce during the study * Antibiotics use in the past month * Ongoing, active ocular infection, including conjunctivitis. * Not having any prior history with Dry eye disease

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder hypersomnia insomnia Sleep Deprivation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Depression Gut microbiota Optometry examinations Oral microbiota Sleep deprivation

Contacts and locations

Locations

  • Private sleep clinic

    Tehran, 1961835555, Iran

More trials for these conditions

Other studies related to the condition(s) this trial covers.