Pistachios before bed: a natural sleep aid?
NCT ID NCT07651605
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether eating 28 grams of pistachios (about 40 nuts) one hour before bedtime could help regulate the body's internal clock in 28 overweight young adults. Researchers measured melatonin levels, antioxidant activity, and sleep-wake patterns. The goal was to see if natural compounds in pistachios, like phyto-melatonin, can influence circadian rhythms.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pistachios (28 g daily, 1 hour before bedtime)
- What this could lead to
- If successful, this could suggest that eating pistachios before bed may help regulate the body's internal clock and improve sleep patterns.
- What could go wrong
- This is a small, completed study with only 28 participants, so results may not apply to everyone. The effect of pistachios on circadian rhythm is still uncertain and needs larger trials.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Nov 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * No diagnosed diseases * Not regularly taking medications that affect melatonin synthesis or body regulation. Exclusion Criteria: * Smokers * Pregnant women * Individuals with night shifts, those following special diets or taking weight loss supplements * People who had undergone recent surgical procedures or significant weight loss in two months before the study. * Those taking sleep medications. * Individuals who had made trans meridian trips within 1 month of the evaluation, * Individuals with allergies, intolerances, or aversions to nuts/pistachios * Participants who voluntarily withdrew from the study * Participants who tested positive for COVID-19 during the intervention * Participants who experienced adverse effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universidad Autónoma de Querétaro
Querétaro City, Querétaro, 76000, Mexico
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