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Can acupressure calm ventilator patients? new trial investigates

NCT ID NCT07619326

Symptom relief Sponsor: Yang Yun Shiuan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether repeated acupressure can help reduce agitation, pain, and sleep disturbances in intensive care unit (ICU) patients who are on mechanical ventilators. Participants receive either real acupressure or a light touch (sham) twice daily for four days. Researchers measure agitation, pain, and sleep using both nurse assessments and wearable devices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acupressure
What this could lead to
If effective, acupressure could offer a drug-free way to ease agitation, pain, and sleep problems in critically ill patients on ventilators.
What could go wrong
This is a small, early-stage trial with only 60 participants. The sham control (light touch) may also have some effect, making it hard to prove acupressure's specific benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2023

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 20 years or older * Admitted to an intensive care unit * Receiving mechanical ventilation via an oral endotracheal tube * Richmond Agitation-Sedation Scale (RASS) score between +2 and +3 * Expected to remain in the ICU for at least 4 consecutive days * Able to receive acupressure intervention as determined by the clinical care team Exclusion Criteria: * planned extubation or ventilator weaning during the study period to ensure a stable clinical condition throughout the intervention period * requirement for deep sedation (e.g., continuous high-dose midazolam or propofol) * severely hemodynamic or respiratory instability (e.g., APACHE II ≥30, heart rate ≥150 beats/min with severe arrhythmia, respiratory rate ≥30 breaths/min, SpO₂ \<90%, or use of high-dose vasopressors with mean arterial pressure ≤50 mmHg) * severe agitation requiring immediate pharmacological restraint * diagnosed delirium, psychiatric disorders, or neurocognitive disorders * bleeding tendency (e.g., platelet count \<20,000/µL) or contraindications to acupressure

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Conditions

The condition(s) this trial relates to.

Critical Illness Pain Parasomnias Psychomotor Agitation sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Agitation Critical illness Mechanical ventilation Pain Sleep wake disorders

Contacts and locations

Locations

  • Official Human Research Protection Program, Changhua Christian Hospital

    Changhua, 50006, Taiwan

More trials for these conditions

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