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Could a simple test spot sleep apnea earlier in down syndrome?

NCT ID NCT03445962

Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study with 40 participants explored factors that might predict obstructive sleep apnea in people with Down syndrome. Researchers used a range of assessments, including sleep studies, heart monitoring, and exercise tests, to identify early warning signs. The goal is to help diagnose sleep apnea sooner, which could reduce fatigue, daytime sleepiness, and heart problems in this population.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to earlier diagnosis of sleep apnea in people with Down syndrome, helping to reduce fatigue, daytime sleepiness, and heart risks.
What could go wrong
This is a small, completed observational study (40 participants) that identifies possible predictors. It does not test a treatment, so any benefits from earlier detection are not proven here.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Nov 2017

Finished

Jul 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults with Down syndome voluntary to participated

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subjects with Down syndrome, able to practice physical activity all participants have received information all have signed the consent form Exclusion Criteria: * pregnant women * Pharmacological treatment altering autonomic nervous system (ANS) * Contra-indication to physical exercise, such as atlanto-axial instability

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Conditions

The condition(s) this trial relates to.

Down syndrome Motor Activity obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Down syndrome Polysomnography Sleep apnea, obstructive

Contacts and locations

Locations

  • CHU Grenoble Alpes

    Échirolles, 38130, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.