SLEEP APNEA, OBSTRUCTIVE

This study tests a once-weekly injection called eloralintide in 800 adults with moderate-to-severe obstructive sleep apnea who are also overweight or have obesity. The goal is to see if the drug can improve breathing during sleep and help with weight loss. Participants will be fo…

This study tests a jaw surgery called maxillomandibular advancement for people with moderate to severe obstructive sleep apnea who cannot use CPAP or mouthpieces. The surgery moves the jaw forward to open the airway, and researchers will check if it improves breathing, reduces da…

This study looks at whether a custom mouthpiece (mandibular advancement device) can help people with obstructive sleep apnea when they temporarily stop using their CPAP machine. About 40 adults who have used CPAP for over a year will be randomly assigned to use the mouth device o…

This study follows 20 people with obstructive sleep apnea who are already using a special nasal airway device. Researchers will check in with participants and have them fill out sleep questionnaires after 12 months. The goal is to see how well the device works over time and if it…

This study looks at whether using a CPAP machine at night can help lower high red blood cell levels (polycythemia) in people with moderate to severe sleep apnea. About 182 adults will be randomly assigned to use CPAP or not, and their blood will be checked over 12 months. The goa…

This study is testing a new device that measures how sensitive the throat is in people who might have obstructive sleep apnea (OSA). The goal is to see if this test can accurately diagnose OSA and its severity. About 117 adults will participate, and the results will be compared t…

This study looks at whether adding a procedure called lateral pharyngoplasty to standard tonsillectomy helps children ages 3-17 recover better. Researchers want to see if it reduces pain, helps kids eat and drink sooner, and lowers the risk of bleeding after surgery. About 160 ch…

This study tests a new device placed in the nose to help adults with moderate to severe sleep apnea who cannot tolerate CPAP. Researchers want to see if the device reduces breathing pauses during sleep. Twenty participants will use the device for 30 days to check if it is comfort…

This study follows 82 children aged 8-18 who have obstructive sleep apnea and are starting positive airway pressure (PAP) therapy. Researchers want to see if insomnia makes kids less likely to use their PAP machines regularly, and how race and ethnicity may influence this. The go…

This study looks at whether breathing through your nose or mouth during sleep changes how much your airway collapses in people with sleep apnea. About 50 adults will have a sleep endoscopy to compare breathing routes. The goal is to better understand sleep apnea and improve diagn…

This study looks at how sleep apnea (pauses in breathing during sleep) affects blood sugar levels in adults with type 1 diabetes. Researchers will monitor 40 participants using continuous glucose monitors to see if sleep apnea makes blood sugar harder to control. The goal is to b…

This study tests a program called REPOSE, which assigns a patient navigator to help families of children with sleep-disordered breathing (like sleep apnea) overcome barriers to getting specialist care. The navigator provides resources, support, and coordinates communication betwe…

This study looks at how well a nerve stimulation device (Inspire) works for people with obstructive sleep apnea who cannot use a CPAP machine. Researchers will measure airway changes during a sleep endoscopy to find out who will benefit most. The goal is to improve success rates …