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Can a gentle brain zap ease multiple mental health conditions?

NCT ID NCT07452835

Symptom relief Sponsor: Menoufia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes using standard rating scales and monitored for side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) device
What this could lead to
If it works, this could offer a non-drug option to reduce symptoms of several psychiatric disorders.
What could go wrong
This is a completed early-stage study without a control group, so results may not be definitive. Side effects like skin irritation or headache can occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

320 people

The number who actually took part.

Started

Jan 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 16 and 65 years * Fulfillment of DSM-5 diagnostic criteria for one of the target disorders * Stable pharmacological treatment for at least four weeks prior to enrollment (if applicable) * Ability to provide informed consent Exclusion Criteria: * History of epilepsy or seizures * Presence of intracranial metallic implants or implanted electronic devices * Severe neurological disorders (e.g., brain tumors) * Pregnancy * Active substance use disorder * Severe cognitive impairment or comorbid psychiatric disorders interfering with assessment

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Conditions

The condition(s) this trial relates to.

anxiety disorder generalized anxiety disorder insomnia major depressive disorder obsessive-compulsive disorder psychiatric disorder schizophrenia schizophrenia 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Generalized anxiety disorder Insomnia Major depressive disorder (MDD) Obsessive compulsive disorder Schizophrenia 1 (disorder)

Contacts and locations

Locations

  • Faculty of Medicine

    Cairo, Menofia, 32511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.