Can a Valerian-Hop pill boost your brain after a bad Night's sleep?
NCT ID NCT05684523
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a herbal supplement called Redormin 500 (made from valerian and hop extracts) can help people with occasional sleep problems think more clearly during the day and feel better overall. Forty healthy adults with mild sleep issues took either the supplement or a placebo for three weeks. The main goal was to see if the study methods worked, not to prove the supplement's effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Valerian-hop extract (Redormin 500)
- What this could lead to
- If it works, this could point toward a natural option to help with daytime thinking and well-being for people who occasionally have trouble sleeping.
- What could go wrong
- This is a small, early feasibility study with only 40 people, so results may not apply broadly. The herbal extract may not improve cognition more than a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
40 people
The number who actually took part.
- Started
-
Mar 2023
- Finished
-
Dec 2023
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy * Male or female * Age: 18-65 years old * Occasional sleep problems (in average 1-2 nights per week, PSQI-score \>5) with accompanying subjective cognitive problems (in average at least on one day per week) in the last month * Fluent in German * Able and willing to give written informed consent and comply with the requirements of the study protocol Exclusion Criteria: * DSM-V diagnosis of insomnia * History of neurologic disorder * Current psychiatric disorder * Presence of moderately severe or severe depressive disorder (PHQ-9 ≥ 15) * Current chronic intake of prescription drugs with psychotropic effects * Current intake of OTC drugs for sleep or mood problems * Presence of pain condition * Diabetes mellitus * Coronary Heart Disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Research Platform MCN University of Basel
Basel, Canton of Basel-City, 4055, Switzerland
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