Wearable ultrasound gadget zaps brain to boost dream sleep

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Healthy Volunteers: \- Adults aged 18-50, willing and able to undergo MRI, EEG, and FUS experiments. Inclusion Criteria for Healthy Volunteers with Non-Clinical Sleep Disturbances: * Adults aged 18-50, willing and able to undergo EEG and FUS experiments. * Pittsburgh Sleep Quality Index (PSQI) score between 5 and 10. * Perceived Stress Scale (PSS) score between 16 and 21. Exclusion Criteria for Both Groups: * Current or past history of psychopathology, epilepsy, or other seizure disorders. * Inability to provide informed consent to undergo EEG recording, FUS stimulation, and MRI. * Diagnosed sleep disorders (e.g., insomnia, obstructive sleep apnea). * Contraindications to FUS or MRI, including but not limited to: history of stroke, brain tumors, brain hemorrhages, internal wires, electrodes, pacemakers, implants, irremovable ferromagnetic objects in the head that are unsafe for MRI and/or cause large imaging artifacts, brain surgery, moderate-to-severe head injury, any penetrating head injury, or uncontrolled thyroid disorder. * Pregnant individuals or those attempting to become pregnant (due to unknown MRI-related risks to fetuses). * Serious medical illnesses likely to interfere with study participation. * Current active suicidal or homicidal ideation (or suicide attempt within the past 3 months). * Current substance use disorder. * Current or recent (within the past 3 months) psychotic symptoms. * Currently meeting diagnostic criteria for a manic episode. * Currently engaged in evidence-based or experimental treatments (e.g., weekly cognitive behavioral therapy, transcranial magnetic stimulation, ketamine/esketamine treatment) other than psychiatric medications that have been on a stable dosage and regimen for at least 3 months (including antidepressants, mood stabilizers, atypical antipsychotics, and sedatives/hypnotics), in order to avoid confounding therapeutic effects.