Female reproductive system disorder

Researchers are testing a vaccine called BNT113 in people whose cancers are driven by HPV16, a common virus linked to head and neck, cervical, and anogenital tumors. The trial enrolls two groups: one with head and neck cancer that has been treated and shows no signs of disease, a…

Researchers are testing whether injecting a woman's own bone marrow cells into her ovaries can restore ovarian function in premature ovarian insufficiency, a condition where the ovaries stop working before age 40. Ten women with the diagnosis will receive the treatment, which inv…

This early-stage study tested a vaccine called DCP-001 in 17 women with a serious type of ovarian cancer who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cells. Researchers measu…

Researchers test whether they can place sutures inside the uterus using a hysteroscope and the X-Tack device. The pilot enrolls women who are already scheduled for laparoscopic hysterectomy for benign conditions. After the sutures are placed, surgeons open the removed uterus to c…

This study looked at whether a special care plan led by a geriatrician and a nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

Researchers are testing a radiation technique called PULSAR in people with metastatic cervical cancer. PULSAR delivers radiation in short bursts to pelvic tumors, guided by imaging, alongside standard systemic therapy. The trial aims to see whether this approach improves overall …

This early-phase trial tested a combination of two chemotherapy drugs (gemcitabine and carboplatin) plus lenalidomide, a drug that blocks blood vessel growth in tumors, in 18 adults with advanced solid tumors, especially urothelial (bladder) cancer. The main goal was to find the …

This phase II trial is testing an oral drug called giredestrant in 30 people with grade 1 endometrial cancer. The goal is to see if the drug can shrink or control the cancer over 6 months. Participants take one pill daily for up to 24 cycles, and doctors monitor tumor changes and…

This early-phase trial tests a new drug called AI-061, which combines two immune-boosting antibodies (anti-PD-1 and anti-CTLA-4) into one treatment. The study will enroll 18 adults with advanced solid tumors that have spread or cannot be removed. The main goals are to find a safe…

This Phase 2 trial tests two experimental drug combinations in 63 women with a specific type of ovarian cancer (BRCA-mutant or HRD-positive) that has worsened after prior PARP inhibitor treatment. Participants receive either tuvusertib plus niraparib or tuvusertib plus larteserti…

This early-stage trial is testing a new drug called tuvusertib, given together with either lartesertib or avelumab, in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see how the body pr…

This study tests whether boric acid vaginal inserts (600 mg) taken for 7 or 14 days can safely and effectively treat yeast infections. About 400 women aged 12 and older with active symptoms will participate. The goal is to see if all signs and symptoms disappear without needing m…

This trial tests an experimental drug called FLX475, given alone or with the immunotherapy pembrolizumab, in people with advanced cancers that have not responded to standard treatments. The study aims to find the safest dose and to see whether the combination can shrink tumors. P…

This trial tests whether a daily fish-derived lipid supplement, taken for 12 weeks alongside standard dietary advice, can reduce inflammation and pain in women with endometriosis. Researchers will randomly assign 46 women aged 18 to 55 with a confirmed diagnosis to either the sup…

This trial tests whether injections of platelet-rich plasma from cord blood can ease vulvar lichen sclerosus, a chronic skin condition causing itching, burning, and pain. Researchers will compare CB-PRP against a placebo in 100 women, giving three treatments four weeks apart. The…

This trial tests whether adding a zinc-containing vaginal gel to the standard yeast infection pill can lower the chance of the infection returning. About 64 women with a current yeast infection will receive either the standard single dose of fluconazole alone or fluconazole follo…

This trial tests an experimental drug called SNS-101, which targets a protein called VISTA that may help tumors evade the immune system. Researchers give SNS-101 alone or with another immunotherapy, cemiplimab, to adults with advanced solid tumors that have not responded to stand…

This trial tests whether giving a higher radiation dose during brachytherapy, a type of internal radiation, can improve local control in patients with locally advanced cervical cancer. Participants receive standard external beam radiation and chemotherapy, plus a boosted brachyth…

This study tested whether thumbtack needle acupuncture can improve ovarian function in 240 women aged 18-40 with diminished ovarian reserve (low egg supply). Participants received acupuncture at specific points for up to 4 weeks. The main goals were to see changes in anti-Mülleri…

This phase 2 trial tested the drug nirogacestat in 53 people with recurrent ovarian granulosa cell tumors, a rare type of ovarian cancer. The goal was to see if the drug could shrink tumors or slow the disease. Participants took nirogacestat orally, and researchers measured how m…

This study tests whether giving menstrual cups to economically vulnerable women in Kenya can lower rates of bacterial vaginosis (BV) and sexually transmitted infections (STIs). The cup is a reusable silicone device that collects menstrual blood and can be worn during sex. Researc…

This phase 2 trial is investigating whether adding an experimental DNA-based therapy called ELENAGEN to the chemotherapy drug gemcitabine can help people with platinum-resistant ovarian cancer. The study will compare the combination against gemcitabine alone, measuring how long p…

This trial tests whether myo-inositol, a natural supplement, can improve fertility treatment outcomes in women with polycystic ovary syndrome (PCOS). Participants take myo-inositol with folic acid or folic acid alone for three months before IVF or ICSI. The study measures egg qua…

This study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is an acceptable and feasible way to treat cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it a…

This pilot trial tests whether a drug called G-CSF, given as a short course of injections, can improve markers of ovarian reserve in women aged 25-40 with premature ovarian insufficiency (POI). The main question is whether treatment can lower FSH levels, raise AMH, and increase a…

This trial compares two methods of amnioinfusion—adding fluid to the womb—in pregnant women with preterm premature rupture of membranes (PPROM) and very low amniotic fluid. One method uses a central venous pressure (CVP) set for controlled fluid delivery, while the other uses the…

This trial tests whether a daily dienogest tablet can shrink endometriomas (ovarian cysts caused by endometriosis) and ease period pain better than a combined oral contraceptive pill. Women aged 18 to 40 with symptomatic endometriomas will take one of the two treatments for three…

This trial investigates an experimental oral drug, LY3143921 hydrate, which blocks a protein called Cdc7 that cancer cells need to divide. It is being tested in adults with advanced solid tumours, including colorectal, ovarian, lung, and pancreatic cancers, that have not responde…

This study looks at whether a traditional Chinese herbal formula, Guishen Yijing, can help women with diminished ovarian reserve (DOR) — a condition where the ovaries have fewer eggs than expected for a woman's age. Researchers will review medical records of 126 women who took th…

This trial tests whether elagolix, a hormone-blocking drug, can shrink endometriomas (ovarian cysts caused by endometriosis) and ease severe period pain better than the combined birth control pill. Women aged 18-40 with symptomatic endometriomas (2-5 cm) will take either elagolix…

This trial is testing a procedure called HIPEC, where a heated chemotherapy drug (cisplatin) is delivered directly into the abdomen after surgery to remove visible cancer. The goal is to find the safest dose that can be used in patients with advanced ovarian, fallopian tube, or p…

This trial compares two surgical strategies for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall and can cause severe bleeding during delivery. One approach is a caesarean hysterectomy, which removes the uterus after the baby is bor…

This virtual trial tests whether a daily prebiotic and probiotic supplement can relieve symptoms of bacterial vaginosis and yeast infections, such as itching, odor, and abnormal discharge. Women aged 25 and older with these concerns will take two capsules daily for 30 days. The s…

This phase 1 trial is testing whether adding the antiviral drug Vistide (cidofovir) to the standard combination of radiation and chemotherapy can improve outcomes for people with HPV-positive cervical cancer. The idea is that Vistide may make cancer cells more sensitive to radiat…

This early-stage trial is testing whether combining two experimental immunotherapy drugs, zalifrelimab and balstilimab, can help shrink or control advanced solid tumors, including cervical cancer. The drugs are designed to block different 'brakes' on the immune system, potentiall…

This study looked at whether giving heated chemotherapy directly into the abdomen during a second-look surgery is possible for people with ovarian, fallopian tube, or peritoneal cancer. Ten participants who had already received standard treatment were enrolled. The goal was to se…

This phase II trial is testing whether the chemotherapy drug eribulin, given alone or combined with the immunotherapy pembrolizumab, can help people with ovarian or uterine carcinosarcoma that has returned or progressed. The study aims to see if these treatments can shrink tumors…

This trial tests whether a 7-day antibiotic course—starting with an intravenous dose of ceftriaxone followed by oral cefixime—can effectively treat acute uncomplicated pyelonephritis (a kidney infection) in women aged 18 to 65. The goal is to see if this shorter regimen works as …

This phase 2 trial tests the drug cabozantinib in women with advanced or metastatic cervical cancer that has worsened after platinum-based chemotherapy. The study aims to see if cabozantinib can control the disease and how safe it is, particularly regarding risks like fistulas. P…

This trial tests whether a daily dietary supplement called WeNatal For Her can improve markers of female fertility in women who are trying to conceive. Forty women aged 18-45 will take three capsules each morning for three menstrual cycles. Researchers will measure blood levels o…

This study tests whether two natural supplements, myo-Inositol and Dioscorea Villosa, can help teenagers aged 14-19 with irregular menstrual cycles, including those with PCOS. The goal is to see if these supplements can make periods more regular. The trial is small, with only 20 …

This trial compares two ways to make the first incision for laparoscopic surgery in women with endometrial cancer: the standard umbilical entry versus entry through the Lee-Huang point, a spot on the upper left abdomen. The goal is to see which approach leads to fewer complicatio…

This trial tests whether taking a specific probiotic supplement (Lactobacillus crispatus Lc-G22) alongside standard antifungal treatment can help prevent repeat vaginal yeast infections. One hundred women with a history of frequent yeast infections will receive either the probiot…

This trial tests whether a soft balloon (Cook's balloon) placed in the cervix is better than a vaginal medication (dinoprostone) for starting labor in full-term pregnancies where the baby is growing slowly. The main goal is to see which method leads to more vaginal deliveries and…

This trial tests an experimental drug, RSO-021, given directly into the chest cavity of people with malignant pleural effusion—a buildup of fluid around the lungs caused by advanced solid tumors or mesothelioma. The study aims to find a safe dose and check for early signs that th…

This study monitors the safety and effectiveness of the drug olaparib (Lynparza) in people with ovarian, breast, prostate, or pancreatic cancer who are prescribed it as part of routine care in South Korea. Researchers will track side effects and how long the cancer stays under co…

This phase II trial tests whether combining two hormone-blocking drugs — onapristone and anastrozole — can shrink tumors or slow cancer growth in women with hormone-receptor-positive endometrial cancer that has not responded to prior chemotherapy. Onapristone blocks progesterone …

This trial tests an experimental drug called enfortumab vedotin, which is designed to seek out and destroy cancer cells that have a specific protein called Nectin-4 on their surface. The study includes people with metastatic urothelial cancer (a type of bladder cancer) and other …

This study tests whether extremely low birth weight infants (born before 29 weeks) who receive donor human milk during their hospital stay have better brain development than those given preterm formula. Infants whose mothers cannot or choose not to breastfeed are randomly assigne…

This early-phase trial tests whether injecting tiny particles called extracellular vesicles, derived from bone marrow stem cells, directly into the ovary is safe for women with premature ovarian failure. The study includes 10 women aged 20–38 who have had no menstrual period for …

This study compares two surgical approaches for laparoscopic hysterectomy in women with benign or premalignant uterine conditions. One method uses a single incision through the belly button, while the other uses three to four small abdominal cuts. The goal is to see which techniq…

This phase 4 trial tests whether a daily combination of myo-inositol and D-chiro-inositol (with folic acid) can improve menstrual regularity and hormone levels in women with polycystic ovary syndrome (PCOS). Sixty women aged 18–45 with PCOS will receive either the inositol combin…

This early-phase trial tests a new drug called PEP-010 in people with advanced solid tumors that have spread. The study checks if PEP-010 is safe alone or with chemotherapy (paclitaxel or gemcitabine). About 57 adults with metastatic pancreatic, ovarian, or other solid cancers wi…

This study tests a new drug called pegilodecakin, a lab-made version of a natural immune protein (interleukin-10), in people with advanced solid tumors such as melanoma, lung, breast, prostate, ovarian, kidney, colorectal, and pancreatic cancers. The drug is given as a daily shot…

This study tested whether giving pregnant women a balanced energy and protein supplement (BEP) can improve birth weight and reduce complications like low birth weight and preterm birth. Over 3,300 women in Bangladesh were randomly assigned to receive either BEP or standard prenat…

This study tests whether a secure website with educational sessions, goal-setting, and tracking tools can help survivors of several cancers (including breast, prostate, colorectal, and others) improve their diet, increase physical activity, and manage weight. Participants are age…

This trial tests whether combining a hormone-releasing IUD with an anchoring IUD can prevent the device from slipping out of place in women with adenomyosis, a condition that causes pelvic pain and heavy bleeding. The study includes 270 women with different uterine cavity depths,…

This trial compares three modern radiotherapy techniques—helical tomotherapy and two types of dynamic arc therapy (RapidArc and VMAT)—for treating prostate, cervical, and anal canal cancers that require pelvic lymph node irradiation. The goal is to determine which method is most …

This trial tests whether repeatedly adding sterile fluid into the womb can help fetuses with severe kidney failure grow enough lungs to survive after birth. Pregnant women with early pregnancy kidney failure can choose to receive the infusions or just be monitored. Babies who sur…

This study tests whether using continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP) during resuscitation helps extremely low birth weight infants (born before 28 weeks) breathe better and avoid lung damage. Half of the babies receive standard care…

This study tested the drug pembrolizumab (Keytruda) as a follow-up treatment for one patient with a rare type of ovarian cancer called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). The goal was to see if the drug could help keep the cancer from coming back. Beca…

This completed phase 2 trial tested whether the drug cediranib, given with chemotherapy, is safe for women with advanced ovarian cancer who are at risk of bowel obstruction. 30 participants received the combination. The study focused on whether the treatment caused serious bowel …

This phase 2 study tested a drug called retifanlimab, which helps the immune system attack cancer, either alone or combined with other targeted drugs. It enrolled 206 women with advanced or metastatic endometrial cancer that had worsened after platinum-based chemotherapy. The goa…

This Phase 3 trial tested whether taking Elagolix (a hormone-blocking pill) for two months before IVF could improve live birth rates in women with endometriosis. 103 women participated, and the main goal was to see if more babies were born after this pre-treatment. The study comp…

This study tested a drug called SB-UF, which combines hormones and a plant extract, to see if it can shrink uterine fibroids in pregnant women. 66 women took the drug or a placebo throughout their pregnancy. The goal was to reduce fibroid size and help them disappear, which could…

This early-phase trial tested a new type of vaccine made from a patient's own immune cells (dendritic cells) that are engineered to target a protein called WT1 found in many cancers. Ten people with advanced esophageal, pancreatic, ovarian, or liver cancer received six vaccines o…

This early-phase study tested whether adding indomethacin, a common anti-inflammatory drug, to standard platinum-based chemotherapy is safe for people with colorectal, esophageal, or ovarian cancers. The 13 participants received escalating doses of indomethacin alongside their ch…

This study compared two surgical approaches for early-stage cervical cancer: laparoscopic-assisted (minimally invasive) and open abdominal hysterectomy. Sixty women with stage IA1 to IB1 cervical cancer were randomly assigned to one of the two surgeries. Researchers measured surg…

This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often g…

This study tested a new technique to help women with primary ovarian insufficiency (early ovarian failure) become pregnant. Doctors removed one ovary, treated small pieces of it with drugs to wake up dormant eggs, and then transplanted the tissue back into the patient. After moni…

This early-phase trial tested a combination of three drugs—olaparib, metformin, and cyclophosphamide—in 35 women with recurrent advanced endometrial cancer that had already been treated with chemotherapy. The goal was to find a safe dose and see if the combination could stop the …

This phase 2 trial tested whether the immunotherapy drug pembrolizumab (Keytruda) could help keep cancer from growing in people with platinum-resistant ovarian, fallopian tube, or peritoneal cancer. After initial chemotherapy with paclitaxel, 20 participants received pembrolizuma…

This study tested a new clinic that sees emergency room patients the next day for conditions like pneumonia, heart failure, and kidney injury. The goal was to avoid hospital stays and improve patient care. About 570 adults took part, and researchers measured how many days they we…

This study tested whether a daily combination pill (relugolix, estradiol, and norethindrone acetate) can prevent pregnancy in women aged 18 to 50 who have uterine fibroids or endometriosis. Over 1,100 women took the pill for up to a year, and researchers counted how many became p…

This study looked at the long-term safety of the cancer drug vismodegib in 19 patients with ovarian cancer, basal cell carcinoma, or metastatic colorectal cancer. All participants had previously taken vismodegib in an earlier Genentech trial and were expected to benefit from cont…

This Phase 3 trial tested a treatment called EryDex for people with ataxia telangiectasia (A-T), a rare genetic disease that affects movement and coordination. EryDex is a steroid (dexamethasone) packaged inside the patient's own red blood cells and given as an IV infusion every …

This phase 3 trial tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy and bevacizumab helps women with advanced, persistent, or recurrent cervical cancer live longer. The study enrolled 410 participants and compared the new combination against the …

This study tested a new experimental treatment called HPVST cells in 32 people with HPV-related cancers that had returned or not responded to standard care. The cells are grown from the patient's own blood and trained to attack HPV-infected cancer cells. The goal was to find a sa…

This study looked at whether a fast blood test (ROTEM) done during surgery for placenta accreta can help doctors decide when to give blood transfusions. 32 women took part, with half getting the rapid test and half getting standard lab tests. The goal was to see if the rapid test…

This study looked at 99 IVF patients with endometriosis (a condition where uterine-like tissue grows elsewhere) and a positive BCL6 test. It compared a cheap oral pill (norethindrone acetate) to an expensive injection (Depo Lupron) given before embryo transfer. The goal was to se…

This Phase 3 trial tested whether taking the drug selinexor as a maintenance pill after chemotherapy can help delay cancer progression in people with advanced or recurrent endometrial cancer. 263 participants who had responded to initial chemo were randomly assigned to receive ei…

This study tested a combination of two drugs, AZD6738 and olaparib, in 123 women with recurrent ovarian cancer. The goal was to see if the combo is safe and how well it shrinks tumors or delays cancer growth. Participants had either platinum-sensitive or platinum-resistant cancer…

This study tested two new antibiotic combinations (cefepime/nacubactam and aztreonam/nacubactam) against the best available treatments for adults with serious infections like urinary tract infections, pneumonia, and abdominal infections caused by carbapenem-resistant bacteria. Th…

This phase 2 trial tested a combination of three drugs—rucaparib, bevacizumab, and atezolizumab—in 30 people with recurrent or progressive endometrial cancer that had not responded to prior treatments. The goal was to see if the combination could shrink tumors or slow the cancer'…

This study tested a handmade frameless IUD that releases the hormone levonorgestrel in 15 women at high risk of IUD expulsion due to conditions like adenomyosis or heavy bleeding. The device was made by combining an anchor system with a standard IUD after removing its T-shaped ar…

This phase 3 trial tested whether a surgical procedure called laparotomy plus heated chemotherapy (HIPEC) could improve outcomes for colorectal cancer patients at high risk of cancer spreading in the abdomen. 150 patients who had already undergone surgery and chemotherapy were ra…

This phase 2 trial tested whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with locally advanced cervical cancer. 189 participants received either the combination or standard treatment alone. The goal was to see if the combination delays …

This study tested whether taking low-dose aspirin (150 mg) daily, starting in the first trimester, could reduce pregnancy complications in women with type 1 or type 2 diabetes. The trial included 137 women and looked at outcomes like preeclampsia, early preterm birth, low birth w…

This study looked at 53 adults with advanced soft tissue sarcoma who had stable disease or improvement after 6 cycles of trabectedin. Half continued the drug, while the other half took a break (drug holiday). The goal was to see which approach better delays cancer progression and…

This study tested a new drug combination (tiragolumab plus atezolizumab) against atezolizumab alone in 172 people with advanced or returning cervical cancer that has a specific marker (PD-L1-positive). The goal was to see if the combination could shrink tumors better. Participant…

This study compared two approaches for inducing abortion in the second trimester for women who have a scarred uterus (e.g., from a previous C-section). One group received a laminaria tent (a seaweed rod that gently opens the cervix) for 12 hours followed by misoprostol pills, whi…

This study looked at 846 women doing their first IVF cycle to compare two drug mixes: follitropin delta plus menotropin versus follitropin alfa plus menotropin. The goal was to see which combination leads to more usable embryos and lower costs. Results help doctors choose the mos…

This study tested an oral antibiotic (tebipenem pivoxil hydrobromide) against a standard IV antibiotic in 1,690 hospitalized adults with complicated urinary tract infections or kidney infections. The goal was to see if the oral pill works as well as the IV treatment in curing the…

This study tested whether a new drug called tisotumab vedotin works better than standard chemotherapy for people with cervical cancer that has spread or returned. Over 500 participants were randomly assigned to receive either the new drug or one of five chemotherapy options. The …

This large phase III trial tested whether using MRI scans to guide internal radiation (brachytherapy) works better than the traditional X-ray method for women with locally advanced cervical cancer. Over 1,000 participants received either MRI-based or X-ray-based brachytherapy. Th…

This study tested whether adding the HIV drug nelfinavir to standard chemoradiation helps people with advanced cervical cancer stay cancer-free longer. About 348 adults with stage III cervical cancer took part. One group got standard treatment, and the other got nelfinavir before…

This study tested whether vaginal capsules containing live lactobacilli (good bacteria) are safe and tolerable for treating bacterial vaginosis (BV), a common infection. Fifty-seven women with BV took either the lactobacillus capsules or the standard antibiotic metronidazole. The…

This study tested whether vaginal probiotic capsules can cure bacterial vaginosis (BV) better than a placebo. 402 women with BV took part. The main goal was to see if more women were cured 21-30 days after treatment with the probiotic compared to placebo. The trial was completed …

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Over 400 participants took either the study drug or a placebo for 12 weeks after an initial treatment, and…

This study tested whether vaginal capsules containing two types of Lactobacillus probiotics can treat bacterial vaginosis, a common vaginal infection. Sixty-six women received either the probiotic capsule or a placebo. The goal was to see if the probiotics could restore normal va…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Participants first received standard treatment for their current infection, then took either oteseconazole…

This completed Phase 3 trial compared two fertility drugs—follitropin delta (Rekovelle) and follitropin alfa (Gonal-F)—in 301 Chinese women undergoing IVF. The goal was to see which starting dose leads to the best number of eggs retrieved. Participants received daily injections f…

This study looked at whether adding vaginal estradiol or oral guaifenesin to standard fertility treatment (clomiphene citrate) could improve pregnancy rates. 90 women with infertility were randomly assigned to one of three groups. The goal was to see if these add-ons helped with …

This study tested whether a simpler version of laparoscopic surgery for pelvic organ prolapse works as well as the standard, more complex technique. 190 women with stage II-IV prolapse were randomly assigned to one of the two procedures. The goal was to see if the simpler method …

This study tested whether two natural supplements (acetyl L-carnitine and myo/chiro-inositol) can help women with PCOS ovulate and become pregnant. 120 women aged 18-35 with PCOS-related infertility took part. The goal was to see if these supplements improve ovulation and pregnan…

This trial studied 211 women with advanced ovarian cancer who were not candidates for upfront surgery. Researchers compared having surgery after 3 rounds of chemotherapy versus after 6 rounds. The goal was to see which timing leads to longer disease-free survival. All patients re…

This phase 3 trial tested whether a newer, more precise type of radiation (image-guided intensity modulated radiotherapy) could reduce long-term bowel problems compared to standard radiation in 300 women who had surgery for cervical cancer. The study focused on lowering severe bo…

This study looked at how effective and safe niraparib is for Korean women with epithelial ovarian cancer. It included 850 patients who took niraparib as maintenance therapy or as a later treatment. Researchers measured how long patients lived without their cancer getting worse an…

This phase 3 study tested whether combining the immunotherapy pembrolizumab with the targeted therapy lenvatinib works better than standard chemotherapy for women with advanced or recurrent endometrial cancer. Over 800 participants received either the drug combo or chemo. The goa…

This early-phase trial tested an experimental drug called VS-6766, given alone or with everolimus, in 104 adults with advanced solid tumors or multiple myeloma that had stopped responding to standard treatments. The goal was to find a safe, tolerable dosing schedule and measure h…

This study looked at whether the HPV vaccine can help prevent high-grade cervical lesions (precancerous growths) in women living with HIV who were already being treated for HPV. About 536 women took part, receiving either the HPV vaccine or a placebo. The goal was to see if the v…

This study tested a new drug called IMP4297 in 93 women with advanced ovarian cancer that has a BRCA1 or BRCA2 gene mutation and has come back after at least two prior treatments. The goal was to see if the drug can shrink tumors or slow the cancer's growth. The drug is taken as …

This study looked at two ways to manage rectal endometriosis in women aged 35-50 who do not plan to get pregnant. One group received hormone therapy for 24 months, while the other had surgery followed by hormones. The goal was to see which approach leads to better digestive funct…

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (a drug that blocks blood vessel growth)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nint…

This phase 2 trial tested a drug called mirvetuximab soravtansine in 79 people with recurrent platinum-sensitive ovarian, peritoneal, or fallopian tube cancers that have high levels of a protein called folate receptor-alpha. The drug is given by IV every three weeks. The main goa…

This trial tested whether a less invasive ultrasound-guided drainage procedure works as well as laparoscopic surgery for treating tubo-ovarian abscess. 208 women with uncomplicated abscess were randomly assigned to one of the two procedures, both combined with antibiotics. The ma…

This study tested whether inositol, a natural dietary supplement, can lower high testosterone levels in women with polycystic ovary syndrome (PCOS). 154 women took either a placebo or one of three doses of inositol powder for a set period. Researchers measured changes in testoste…

This phase 3 trial tested two new antibiotic combinations—cefepime/nacubactam and aztreonam/nacubactam—against a standard antibiotic (imipenem/cilastatin) in 614 adults with complicated urinary tract infections or acute kidney infections. The goal was to see if the new combos are…

This study followed 86 women under 40 with premature ovarian failure (early menopause) who had received a one-time gene therapy using their own stem cells. The goal was to check long-term safety and see if hormone levels and fertility improved over 2.5 years. No new treatment was…

This study tested whether freezing eggs (oocyte cryopreservation) could help preserve fertility in women with benign ovarian cysts that often come back, like endometriomas. The 82 participants had cysts that required multiple surgeries, which can damage the ovaries. Researchers m…

This study tested a drug called avelumab in 24 women with a rare pregnancy-related cancer (GTN) that did not respond to standard chemotherapy. The goal was to see if the drug could lower tumor markers (hCG) to normal levels and allow treatment to stop. Avelumab works by helping t…

This study looked at 120 vulnerable women over 70 with advanced ovarian cancer. It compared three chemotherapy plans: standard two-drug therapy every three weeks, a single drug every three weeks, or a weekly two-drug schedule. The goal was to see which plan allowed patients to co…

This study tested whether giving the immunotherapy drug nivolumab directly into the abdomen is safe after extensive surgery and heated chemotherapy (HIPEC) for advanced ovarian cancer. 22 adults with recurrent ovarian, peritoneal, or fallopian tube cancer took part. The goal was …

This study looked at 130 women with endometriosis who froze their eggs. It compared a drug called dienogest against standard hormone treatments to see if it could collect a similar number of mature eggs. The goal is to find a simpler, effective option for fertility preservation i…

This early-phase trial tested a personalized immunotherapy for people with advanced solid tumors. Doctors removed a sample of each patient's tumor, grew the immune cells (TILs) in a lab, and then infused them back along with another drug. The goal was to see if this approach is s…

This study tested two immunotherapy drugs, durvalumab and tremelimumab, given with chemotherapy before and after surgery for advanced ovarian cancer. The goal was to see if this combination is safe and feasible. About 69 women with stage IIIC to IV ovarian cancer took part. The r…

This study tested a combination of two drugs, pembrolizumab and lenvatinib, against standard chemotherapy for women with advanced or recurrent endometrial cancer. The goal was to see if the combo could slow cancer growth or improve survival better than chemo. The trial enrolled 1…

This study looked at 88 pregnant women whose water broke before labor started, comparing those who got labor-inducing gel right away versus those who waited 24 hours. The goal was to see which approach led to shorter labor and more vaginal deliveries. The findings could help guid…

This study tested whether an oral probiotic supplement could help restore healthy bacteria in the vagina. It included 32 women aged 35-43 with vaginal imbalance and fertility concerns. Researchers measured how well the probiotic colonized the body and its effects on immune and an…

This phase 2 trial tested whether adding the targeted drug cetuximab to standard chemoradiation (cisplatin plus radiation) improves outcomes for people with locally advanced cervical cancer (stages IB2 to IIIB). 76 participants were randomly assigned to receive either chemoradiat…

This study compared two treatments for symptomatic uterine fibroids—surgery (myomectomy) and a minimally invasive procedure (uterine artery embolization)—to see which one better helps women get pregnant and have a live birth. It included 9 women aged 18 to 43 with fibroids larger…

This early-stage study tested whether a single injection of stem cells from donated umbilical cords is safe for women with premature ovarian insufficiency (early menopause). Only 6 women took part, and the main goal was to check for side effects, not to prove it works. Researcher…

This study looked at whether giving more red blood cell transfusions (liberal strategy) to extremely low birth weight babies (under 1000 grams) helps them survive without brain damage compared to a more restrictive approach. Over 1800 infants from NICUs were followed until 22-26 …

This study tested a smartphone app to help young adult cancer survivors (ages 18-39) lose weight. The app tracked diet and activity as part of a behavioral weight loss program. The goal was to see if this approach was practical and well-liked by participants. The study involved 6…

This study tested a shorter course of pelvic radiation (about 1 week instead of the usual 5-6 weeks) given after hysterectomy for advanced endometrial cancer. The goal was to see if this shorter treatment causes fewer side effects while still controlling the cancer. The study inc…

This study tested a vaginal pessary (Gedea) in 26 women with yeast infections. Participants used the device daily for 6 days. Researchers checked if symptoms like itching and burning went away by day 7 to 14. The goal was to see if the device could safely treat the infection with…

This study looked at 60 women with deep endometriosis in the rectum to compare two surgical approaches: removing the affected part of the rectum versus just cutting out the endometriosis nodules. The goal was to see which method leads to fewer long-term bowel and bladder problems…

This early study tested whether a naturally occurring hormone called kisspeptin can stimulate reproductive hormones and help women with hypothalamic amenorrhea (a condition where periods stop due to low hormone levels) release eggs. Thirteen women received pulsatile injections of…

This study tested whether placing two stitches instead of one around the cervix during an emergency can help women with a weak cervix carry their pregnancy longer. The trial included 81 women between 16 and 25 weeks of pregnancy whose membranes were bulging out. The goal was to s…

This study tested whether platelet-rich plasma from umbilical cord blood can thicken the endometrium (uterine lining) in women with Asherman's syndrome or endometrial atrophy. Fifteen women received an injection of the plasma into the uterine wall during a hysteroscopy, along wit…

This early-phase study tested whether adding the immunotherapy drug nivolumab to standard chemoradiation is safe for people with locally advanced cervical cancer. Twenty-one adults received nivolumab alongside cisplatin and radiation, followed by up to six months of nivolumab alo…

This Phase 2 trial tested whether adding afuresertib (an AKT inhibitor) to standard paclitaxel chemotherapy helps control platinum-resistant ovarian cancer better than paclitaxel alone. 150 women with this difficult-to-treat cancer participated. The study measured how long the ca…

This phase II trial tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy before surgery helps women with stage IV ovarian cancer. 91 participants received either chemo alone or chemo plus pembrolizumab, followed by surgery. The goal was t…

This early-phase trial tested a new drug, Karonudib, in 63 people with advanced solid tumors that had not responded to standard treatments. The main goal was to check the drug's safety and find the best dose. Researchers also looked at how the drug moves through the body and any …

This study tested whether a daily capsule of cranberry, hibiscus, vitamin C, and lactobacillus could lengthen the time between a pregnant woman's waters breaking early (between 24 and 34 weeks) and delivery. 84 women were randomly assigned to receive either the supplement or a pl…

This early-phase trial tested the combination of two drugs—trabectedin and durvalumab—in 40 people with advanced soft-tissue sarcoma or ovarian cancer that had not responded to prior treatments. The main goal was to find a safe dose and check for side effects. Researchers also lo…

This early-phase trial tested an experimental immunotherapy called ELI-002 in 25 people with KRAS-mutated pancreatic, colorectal, lung, ovarian, or bile duct cancers who had signs of remaining disease after standard treatment. The therapy aims to train the immune system to attack…

This study followed over 1,500 women with moderate to severe uterine fibroids who were taking Esmya (ulipristal acetate) long-term. Researchers tracked side effects, especially those affecting the uterus, and how doctors prescribed the drug in everyday practice. The goal was to b…

This study tested whether using a special bag during laparoscopic fibroid removal (myomectomy or hysterectomy) can prevent the spread of cells that might be cancerous. Forty-eight women were randomly assigned to have the procedure with or without the bag. Researchers then checked…

Researchers in Cameroon are comparing a new smart speculum with a standard speculum to see which gives better comfort for women and clearer views of the cervix. Each participant receives both exams in random order, and clinicians use the smart speculum's images to make remote dia…

This study tests Cellvizio, a device that provides real-time, high-resolution views of tissues during gynecological surgery. Researchers want to see if it can help diagnose lesions and check surgical margins more accurately. The study will enroll 80 women undergoing laparoscopic …

This trial tests whether indocyanine green, a dye injected before surgery, can find sentinel lymph nodes as reliably as the standard technetium-99 radioactive tracer. About 744 adults with various cancers will receive both agents, and surgeons will compare detection rates using a…

This trial tests whether a vaginal self-sampling device can accurately detect high-risk human papillomavirus (HPV) compared to samples collected by a clinician. About 1,000 women aged 30-64, either regular screening attendees or those who haven't been screened in 3+ years, will p…

This trial is testing whether 3D ultrasound can diagnose placenta accreta spectrum more accurately than the standard 2D ultrasound with color Doppler. Placenta accreta is a serious pregnancy condition where the placenta grows too deeply into the uterine wall, which can cause seve…

This study is testing whether a simple blood test can help doctors tell apart two main causes of intrauterine growth restriction (IUGR) — a condition where a baby grows slower than expected in the womb. The test measures the ratio of two proteins, sFlt-1 and PlGF, which are linke…

This trial tests whether a green dye, injected during keyhole surgery to remove benign ovarian cysts, can show how well the ovary is still getting blood flow. The idea is that better blood flow might mean the ovary is healthier and more likely to support a future pregnancy. Women…

This study looks at whether a blood test that detects tumor DNA can find early signs of cancer returning in people treated for HPV-positive pelvic cancers (like cervical or anal cancer). Researchers will take blood samples from 172 patients during regular follow-up visits. The go…

This study tested whether a special MRI technique called susceptibility weighted imaging (SWI) can better detect endometriosis lesions before surgery. Endometriosis spots often contain old blood, which SWI is good at seeing. Researchers compared SWI-MRI findings with what surgeon…

This study looked at whether women would be willing to collect their own urine sample for cervical cancer screening instead of a traditional swab. 173 women aged 31-49 at a French hospital tried it and answered questions about their experience. The goal was to see how acceptable …

This study looked at whether PET scans can better detect endometriosis lesions before surgery compared to standard MRI and ultrasound. Fifteen women with symptomatic endometriosis scheduled for surgery received a PET scan, and the results were compared with what surgeons actually…

This study tested whether a rapid point-of-care test (Xpert® Xpress MVP) helps doctors diagnose vaginal infections more accurately than usual methods. 351 women with symptoms like discharge or itching were randomly assigned to either usual care or the rapid test. Researchers then…

This study looked at 45 patients whose HPV tests came back negative but had a late signal in the raw data. Researchers wanted to see if these late signals might actually indicate early cervical cell changes. By comparing different lab methods, they aim to improve how we interpret…

This study tested a new way to screen for cervical cancer using samples women collect themselves at home. Researchers wanted to see if a test that looks at DNA changes in HPV could better identify who truly needs follow-up care. About 294 women participated, and the goal was to m…

This study looked at whether a substance in the blood called adropin can help identify placenta accreta spectrum, a serious condition where the placenta grows too deeply into the womb. Researchers measured adropin levels in 84 pregnant women—42 with the condition and 42 healthy—t…

This study tested a new colposcopy method that uses a scoring system (Swede score) to better diagnose cervical precancer in women with abnormal screening results. Researchers enrolled 929 women referred for colposcopy to see if the scoring system could accurately identify precanc…

This completed study looked at whether certain molecules in the blood (kisspeptins and miRNAs) can help diagnose non-viable pregnancies, including ectopic pregnancies. Researchers collected blood samples from 433 women to measure these biomarkers. The goal is to develop a more ac…

This study looked at whether giving family doctors a small, portable ultrasound machine helps them diagnose and manage eight common conditions (like pneumonia, kidney stones, and pregnancy issues) without needing extra tests. Over 160 patients took part, and researchers compared …

This study aimed to create a quick, simple test to diagnose tuberculous meningitis (TBM) in children. TBM is a severe form of TB that affects the brain and is hard to detect with current methods, especially in places with limited resources. Researchers tested 51 inflammatory mark…

This study looked at whether adding a new tumor marker (HE4) and using special scoring systems (ROMA and RMI) can better tell the difference between harmless ovarian cysts and ovarian cancer. Researchers measured CA125 and HE4 levels in 221 women scheduled for ovarian cyst surger…

This study looked at whether a protein called EG-VEGF in the blood of pregnant women could predict pre-eclampsia or poor fetal growth. Researchers took blood samples and performed ultrasound scans on 142 women early in pregnancy. The goal was to see if EG-VEGF levels could serve …

This study tested whether functional MRI can detect differences in oxygen flow in the placenta and fetus between healthy pregnancies and those with intrauterine growth restriction (IUGR). Pregnant women breathed pure oxygen while MRI scans measured the BOLD effect, a signal chang…

Researchers are testing whether a brief educational session helps Latina women who are overdue for cervical cancer screening use a mailed HPV self-sampling kit. Half of the participants receive the kit alone, and the other half also join a small-group session with a bilingual hea…

This study tests whether women in Kazakhstan will accept self-sampling kits for HPV detection, a key step in preventing cervical cancer. Researchers will distribute three different self-sampling devices to 1,000 women and survey their willingness to use them. The goal is to see i…

This large school-based study in Cambodia and Kenya tests whether adding age-appropriate lessons about HPV, the HPV vaccine, and cervical cancer to existing health classes can increase vaccination coverage and improve students' knowledge and attitudes. About 9,000 students in gra…

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only…

This study tests whether limiting daily eating to an 8–10 hour window can improve metabolic health and potentially lower the risk of endometrial cancer. Overweight or obese Native Hawaiian/Pacific Islander women at elevated risk will follow a time-restricted eating schedule for s…

This study tested a program called Game Changers for Cervical Cancer Prevention (GC-CCP) in Uganda. It trained women who had already been screened to encourage their friends and family to get screened too. The trial involved 936 participants and compared the program to usual care…

This study tested whether giving albumin and furosemide right after egg retrieval can prevent severe ovarian hyperstimulation syndrome (OHSS) in women at high risk during ICSI. OHSS can cause swelling, fluid buildup, and sometimes hospitalization. The trial involved 200 women and…

This study looked at whether giving the Gardasil 9 HPV vaccine to women at the same time as surgery for abnormal cervical cells (CIN) can help clear the virus and prevent future infections. About 1,100 women aged 18-55 took part. The goal was to see if the vaccine reduces the cha…

This study tested whether offering a vaginal self-sampling kit directly to women aged 50-65 who had not had a cervical smear in over three years would increase screening participation. Women received a kit to use at home and mail to a lab for HPV testing. The goal was to see how …

This study tested a two-step screening process to find postmenopausal women at higher risk for endometrial cancer. Those identified as high-risk received a hormone challenge test and, if positive, standard care plus a lifestyle program. The goal was to see if this approach is pra…

This study looked at 820 pregnant women at high risk for early labor who had a cervical stitch (cerclage). Researchers compared two ways of giving progesterone—shots into muscle versus rectal suppositories—to see which better prevents preterm birth before 37 weeks. The goal was t…

This study tested whether taking a low-dose aspirin (160 mg) each night, starting before 16 weeks of pregnancy, could prevent pre-eclampsia and small babies in first-time mothers at high risk. Over 1,100 women with abnormal blood flow in the uterine artery were randomly assigned …

This study tested whether giving an antibiotic (clindamycin) to pregnant women with bacterial vaginosis (a common vaginal infection) before 13 weeks of pregnancy could lower the chance of very early preterm birth. Over 3,000 pregnant women took part. The goal was to see if early …

This study tested whether mailing HPV self-test kits to women who are overdue for cervical cancer screening could increase participation. Over 2,400 underserved women in Texas were randomly assigned to receive a kit or standard phone reminders. The goal was to see if the at-home …

This study tests whether using a special monitor (ANI) during ovarian cancer surgery to guide pain medicine can lower the chance of chronic pain three months after the operation. About 126 women having open surgery for ovarian cancer will be randomly assigned to standard care or …

Researchers are testing whether a probiotic capsule taken by mouth can reduce vaginal odor in healthy women aged 18 to 65. About 105 participants receive either the probiotic or a placebo for 15 days and answer weekly questionnaires plus a daily diary for roughly 75 days. The tri…

This trial compares a new treatment combining a woman's own platelet-rich plasma with hyaluronic acid against standard local estrogen therapy for genitourinary syndrome of menopause. It enrolls 192 sexually active women up to age 70 who have vaginal dryness, burning, or discomfor…

Researchers are testing whether adding interferential current or kinesio taping to pelvic floor muscle exercises helps women with primary dysmenorrhea. Sixty women aged 18 to 30 will be randomly assigned to one of three groups: exercises alone, exercises plus interferential curre…

This trial tests whether drinking lavender herbal tea twice daily for nine days around each menstrual cycle can reduce the emotional and physical symptoms of premenstrual syndrome (PMS), such as anxiety, depression, stress, and pain. Sixty women with PMS will be randomly assigned…

Researchers at the University of Oklahoma are testing a mobile health program designed to help adults receiving chemotherapy for metastatic breast or gynecologic cancer stay physically active. The program combines a wearable activity tracker, behavior change techniques, acceptanc…

Researchers are testing whether adding pain neuroscience education to a six-week exercise program helps women with primary dysmenorrhea, the recurring menstrual pain that is not caused by another condition. Sixty-two women aged 18 to 35 join the trial and are split into two group…

Researchers are testing whether adding alpha-lipoic acid, an antioxidant supplement, to standard letrozole treatment helps infertile women with polycystic ovary syndrome ovulate and become pregnant. The trial enrolls 150 women aged 18 to 35 who are trying to conceive. Both groups…

Ataxia-telangiectasia is a rare, inherited disease that damages the nervous system, skin, and immune system, and it has no cure. Researchers are testing sirolimus, an immune-suppressing drug, in children under 17 with the condition. The six participants take sirolimus by mouth fo…

This study tests whether adding a special yoga and physiotherapy program to standard care can lower stress in women receiving brachytherapy for cervical cancer. About 98 women will take part. The program includes gentle movement and breathing exercises designed to be safe during …

This study tests whether a single session of physical activity, physical therapy, or a combination of both can improve how women with endometriosis perceive their bodies and physical abilities, with the goal of boosting overall quality of life. Researchers will enroll 52 menstrua…

This study tests whether a 5-minute educational video about uterine fibroids and their treatments can help patients feel less conflicted when deciding on a treatment plan. About 154 women with fibroids will be randomly assigned to watch the video before their appointment or recei…

This trial tests whether suspended moxibustion, a traditional therapy that holds a burning moxa stick near the skin, can reduce pain from primary dysmenorrhea, or period cramps without an underlying disease. Researchers plan to enroll 48 female students aged 18 to 35 who have mod…

This study tested whether regular footbaths during the luteal phase (the week or two before a period) could help women with premenstrual syndrome (PMS). 92 women participated, with one group receiving footbath therapy and the other receiving no treatment. Researchers measured sym…

This trial tests whether peer education based on the Health Belief Model helps female university students cope with premenstrual syndrome (PMS). About 50 students with PMS will be randomly assigned to either receive two biweekly classroom sessions led by peers, covering PMS cause…

This study looked at whether yoga can reduce pelvic pain and improve quality of life for women with endometriosis. Sixty women who had pelvic pain for at least six months took part. They practiced yoga and reported their pain and well-being using standard questionnaires. The goal…

This trial tests whether progressive muscle relaxation, kinesio taping, or both can reduce premenstrual syndrome symptoms like stress, depression, and poor sleep in university students. Participants are randomly assigned to one of four groups: relaxation exercises, taping, both, …

This trial tests whether a six-session educational program, based on Orem's Self-Care Theory, can improve self-care and menstrual hygiene in adolescent girls aged 15-17 with primary dysmenorrhea (period pain). Participants receive the program over four weeks, while a control grou…

This trial tests whether sleeping next to a traditional Chinese herbal sachet—a cloth bag filled with a blend of 13 aromatic herbs—can reduce menstrual pain and improve anxiety and depression in female college students with primary dysmenorrhea (painful periods without an underly…

This study tests whether a 16-week digital pelvic floor rehabilitation program is feasible for women who have been treated for cervical cancer within the past five years. The program includes supervised group exercise sessions and home exercises, along with information on dilator…

This study asks whether adding acupuncture to a multidisciplinary treatment plan can reduce pain and improve quality of life for women with vulvodynia or chronic pelvic pain lasting at least six months. Half of the participants will receive acupuncture sessions, while the other h…

This study tests whether a non-ablative radiofrequency treatment can improve vaginal tissue health and reduce symptoms of Genitourinary Syndrome of Menopause (GSM), such as dryness and discomfort, in postmenopausal women. Participants will be randomly assigned to receive either t…

This early-stage trial is testing whether a topical solution containing calcitriol, a form of vitamin D, can safely reduce hair loss in adults receiving taxane-based chemotherapy for breast, gynecologic, or other solid tumors. Participants apply the solution to their scalp twice …

This trial tests whether a 12-week structured physiotherapy program—including stretching, aerobic jogging, Kegel exercises, and relaxation—can reduce the severity of period pain in 360 female physical therapy students with primary dysmenorrhea. Participants are randomly assigned …

This study tests four different vaginal treatments (estrogen, DHEA, estrogen with probiotics, and a moisturizer) in 160 breast cancer patients who have vaginal atrophy due to hormone therapy. The goal is to see which treatment best relieves symptoms like dryness and pain, and imp…

This trial tests whether combining breathing exercises with core stabilization exercises relieves menstrual pain better than core exercises alone. It enrolls 48 women aged 18–25 with primary dysmenorrhea, who will attend supervised sessions three times a week for eight weeks. Res…

This study tests a psychosocial program called Conquer Fear Support (CFS) for people with stage III or IV lung or gynecologic cancer who are experiencing fear of cancer progression. The program includes psychoeducation, attention training, worry management, and detached mindfulne…

This trial tests whether an ultrasound-guided erector spinae plane block can reduce pain and the need for opioids during and after cesarean sections in women with placenta accreta, a condition where the placenta grows too deeply into the uterine wall. Participants will receive th…

This study looks at whether a program called prehabilitation—which helps patients get stronger and healthier before surgery—can lower the chance of problems after surgery for advanced ovarian cancer. About 146 women having surgery for ovarian cancer will take part. The goal is to…

This trial investigates whether adding electroacupuncture to a daily nutritional supplement can reduce the severity of premenstrual syndrome (PMS) in young women aged 20 to 29. Participants receive either the supplement alone or the supplement plus 21 sessions of electroacupunctu…

This pilot study tests if a gentle massage technique called manual lymphatic drainage (MLD) can reduce period pain in young women aged 18-25 with primary dysmenorrhea. Twenty participants will receive three monthly MLD sessions before their period. Researchers will measure pain, …

This trial investigates whether a 20-minute warm-water footbath containing magnesium sulfate can reduce pain in women with primary dysmenorrhea (painful periods). Around 120 women aged 18–35 are randomly assigned to receive the magnesium footbath, a plain warm-water footbath, or …

This study is testing whether a daily cream (7-0940®) can safely improve symptoms of vaginal atrophy in 10 women who have already completed laser therapy. Researchers will check vaginal health, quality of life, and any side effects over 45 days. The goal is to see if the cream he…

This study tested a 4-week exercise program before surgery (prehabilitation) in 34 women with cervical cancer. The program included aerobic, resistance, and pelvic floor exercises. Results suggest it may improve pelvic floor strength and shorten hospital stays compared to standar…

This study tests whether high-intensity laser therapy (HILT) can reduce pain during intercourse for women with provoked vestibulodynia, a condition causing severe pain at the vaginal opening. About 145 women with moderate to severe pain will receive either real or sham laser trea…

This study tests whether a podcast-based education program can reduce the severity of premenstrual syndrome (PMS) symptoms and improve quality of life in female university students. Participants listen to eight podcast episodes over four weeks that cover topics like understanding…

This trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive o…

This study tested a small pellet placed under the skin that slowly releases a hormone called gestrinone to treat pelvic pain caused by endometriosis. About 100 women with confirmed endometriosis and ongoing pain after surgery took part. The goal was to see if the pellet is safe a…

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This study tested whether a structured cognitive behavioral therapy (CBT) program could reduce psychological distress and improve problem-solving skills in women with vaginismus. Sixty women were randomly assigned to either CBT sessions over three months or routine care. The resu…

This study looked at whether a one-hour hypnosis session, done 5 to 15 days before a hysterectomy for pelvic gynecological cancer, could lower anxiety around the time of surgery. Twenty-nine women participated, and the hypnosis was guided by a trained nurse. The main goal was to …

This study tested a new medication called OG-6219 in 354 women aged 18 to 49 with moderate to severe endometriosis-related pain. The goal was to see if three different doses could safely reduce pelvic pain compared to a placebo. The trial is complete, and results will show how we…

This study tested a 3-month treatment with a combination of vitamin D, green tea extract (EGCG), vitamin B6, and D-Chiro-inositol in 108 women with uterine fibroids who were planning surgery. The goal was to see if the supplement could ease symptoms and possibly help some women a…

This completed study tested whether a special pain monitor (NOL index) could help doctors give the right amount of pain medication during laparoscopic endometriosis surgery. The goal was to reduce total painkiller use and improve recovery. The study included 125 premenopausal wom…

This study compared two types of minimally invasive hysterectomy: vNOTES (done through the vagina) and conventional laparoscopic hysterectomy (done through small belly cuts). About 90 women having hysterectomy for non-cancer reasons took part. The goal was to see which method cau…

This study compared progressive relaxation exercises (tensing and relaxing muscles while breathing) with isometric exercises (holding muscle contractions) for managing period pain. Sixty women with moderate to severe primary dysmenorrhea took part. Researchers measured pain, othe…

This pilot study tested a portable TENS device for reducing menstrual pain in 34 women with primary dysmenorrhea. Participants used the device on their lower abdomen during pain episodes for up to three cycles. The goal was to see if this drug-free approach could ease pain and im…

This pilot study tested whether giving two medications (mifepristone and misoprostol) at the same time helps women deliver faster after a nonviable second-trimester pregnancy, compared to misoprostol alone. Thirty women between 14 and 28 weeks pregnant who needed labor induction …

This study tested a new way to follow up with gynecologic cancer survivors. Instead of seeing a doctor every time, patients saw a nurse at every other visit and used a smartphone app to help manage their health. The goal was to see if this approach improved self-management skills…

This small pilot study looked at whether acupuncture given twice before surgery could help stabilize blood pressure in women having their uterus removed (total laparoscopic hysterectomy) for fibroids. Thirty-five adult patients received acupuncture before the operation, and resea…

This study tested a home-based cognitive training program called BrainHQ in 60 women with gynecologic cancers who had memory or thinking problems after chemotherapy. Participants used the app for about 2.5 hours per week for 10 weeks. The goal was to see if the program was practi…

This study tested whether placing a small drain in the belly to remove leftover gas after laparoscopic gynecologic surgery reduces shoulder and rib pain. 202 women were randomly assigned to get the drain or standard manual gas release. The goal was to see if fewer women in the dr…

This study tested whether adding ketoprofen to standard paracetamol (acetaminophen) can better control pain in patients receiving brachytherapy for cervical or upper airway/digestive tract cancers. Sixty-eight adults were randomly assigned to receive either paracetamol alone or p…

This study tested a program called PEEPS for people with endometriosis-related pelvic pain. Over eight weekly sessions, participants learned about mindfulness, yoga, nutrition, and pain coping strategies, while getting support from peers and clinicians. The goal was to see if the…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested Korean manupuncture, a hand-based therapy, for reducing pain in women with endometriosis. 74 women were randomly assigned to receive either real or placebo sessions. The goal was to see if this gentle, non-drug approach could help manage pain that often doesn't …

This study tested whether a combination of slow, guided breathing (called cardiac coherence) and a hypnosis session could help women feel less anxious before breast or gynecologic cancer surgery. Fifty-three women participated, practicing the breathing technique several times a d…

This study tested whether a nerve block (stellate ganglion block) combined with standard anesthesia could help women with uterine fibroids sleep better and feel less anxious after laparoscopic surgery. 233 women aged 35-55 took part. Results aim to show if this approach reduces s…

This study compared two surgical techniques for removing the uterus (hysterectomy) due to non-cancerous conditions: the newer vNOTES method (done through the vagina) and standard laparoscopy (keyhole surgery). 145 women took part, and researchers tracked complications, pain, and …

This study tested whether a 12-week adapted physical activity program could improve health-related quality of life in 51 women with endometriosis in Martinique. The program included aerobic, strength, and flexibility exercises. Researchers measured changes using a standard endome…

This phase 2 trial tested whether the drug letrozole can reduce pain during ovarian stimulation in 60 women with endometriosis. Participants received either letrozole or a placebo daily, and researchers measured changes in pain scores. The goal is to find a way to make fertility …

This study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…

This study tested a program that teaches couples communication skills when one partner has advanced cancer. About 440 patients and their partners took part, with half receiving the training and half getting general healthy living information. The goal was to see if the training c…

This study tested whether a non-invasive brain stimulation method called tDCS can help relieve chronic pelvic pain in women with endometriosis. Thirty women who were already on hormone therapy and had daily pain scores above 4 out of 10 took part. They received multiple tDCS sess…

This study tested whether using virtual reality (VR) during a trans-vaginal ultrasound could help women with endometriosis feel less anxious and experience less pain. 155 women were randomly assigned to either use VR for relaxation during the exam or receive standard care. Resear…

This study tested whether giving an anti-inflammatory steroid directly into the uterine arteries during a non-surgical fibroid treatment can lessen pain, nausea, vomiting, and tiredness afterward. Forty-two women with symptomatic fibroids took part. The goal was to see if this si…

This study tested whether injecting the numbing drug ropivacaine into the belly and around a nerve cluster before surgery can lower pain after laparoscopic fibroid removal. 207 women having fibroid surgery were randomly assigned to get either ropivacaine or a placebo. The main go…

This study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…

This study tests whether injecting platelet-rich plasma (PRP) from a woman's own blood into the vulvovaginal area can relieve symptoms of genital atrophy like dryness, burning, and pain during sex. It includes 30 women who cannot use standard hormone treatments. Half receive PRP …

This study looked at whether two sessions of hypnosis could lower anxiety in pregnant women with preterm premature rupture of membranes (PPROM). 60 women took part, with some receiving hypnosis and others standard care. The goal was to see if hypnosis helps reduce anxiety and imp…

This study looks at whether a new pain management approach helps people going through in vitro fertilization (IVF) feel less pain. Researchers will compare pain scores from 206 patients to those from an earlier study. The goal is to see if the updated care plan reduces discomfort…

This study tested a new device called a hysteroscopic morcellator against the standard resectoscope for removing uterine polyps. The goal was to see which method is faster and safer. The trial involved 90 adults with a single polyp. The morcellator uses suction and mechanical cut…

This study tested whether an online education program helps gynecologic cancer patients better manage side effects after brachytherapy. 150 patients were randomly assigned to receive either the online program plus standard care or standard care alone. The goal was to see if the p…

This pilot study tested whether taking a combination of EGCG (from green tea), vitamin D, and D-chiro-inositol for three months before hysteroscopic myomectomy improves surgical outcomes. 90 women with uterine fibroids were divided into two groups: one received the supplements be…

This study tested a 3-month program combining yoga and pelvic floor physiotherapy for women with endometriosis. 82 women started, and 50 completed the program. Researchers measured changes in chronic pelvic pain, painful sex, and quality of life using questionnaires. The goal was…

This study looked at whether music therapy could help college students with premenstrual syndrome (PMS). Twenty participants were split into three groups: one listened to calming music, one sang, and one played instruments. Researchers measured their brain waves, heart rate, musc…

This study tested a cream called MC2-25 to see if it can safely reduce itching in women with vulvar lichen sclerosus, a skin condition that causes discomfort. 33 women used either the active cream or a placebo for 12 weeks. The main goal was to measure how much the worst itching …

This study tested a mobile app designed to help doctors keep track of symptoms in women with advanced ovarian cancer. Ten patients used the app, which combined their medical records with regular symptom reports. The goal was to see if this information helped the care team make be…

This study tested two drugs, letrozole and danazol, to see which better reduces pelvic pain in women with endometriosis. Sixty women aged 18-45 with moderate to severe pain took one of the two drugs daily for 12 weeks. The main goal was to measure changes in pain scores, with the…

This study tested whether paroxetine, a common antidepressant, can reduce hot flashes and night sweats in women who entered menopause after surgery. 90 women took either paroxetine or a placebo daily for 6 months. The goal was to see if paroxetine could be a safer alternative to …

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily…

This early-stage trial tested a vaginal gel containing diclofenac, a common pain reliever, in 42 women with painful periods. The gel is designed to deliver the drug locally, potentially reducing side effects. The study focused on safety and how much drug enters the blood and vagi…

Children with growth hormone deficiency often need daily injections, which can be hard to keep up with. Researchers in Belgium and Luxembourg are asking families in the BELGROW registry to fill out a questionnaire about whether they would consider switching to long-acting growth …

Researchers at Ghent University Hospital are studying whether MRI scans combined with computer models can measure the pressure inside tumors. High pressure in tumor tissue can block cancer drugs from reaching their target. The study enrolls 22 patients with pancreatic cancer or w…

This study gives questionnaires to patients, interpreters, and healthcare professionals to understand how language and cultural differences impact care for women with gynecologic cancer. The goal is to identify barriers and improve the patient experience. About 45 people will tak…

This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer before they start chemotherapy. Using CT scans, researchers want to see how common this condition is and if it affects treatment timing. The goal is to better understand how muscle health rela…

This study aims to understand why testicular cancer sometimes runs in families. Researchers will collect DNA samples and medical information from about 750 people in families with multiple cases of testicular cancer. No treatment is given; the goal is to find genes that increase …

This completed study enrolled 377 individuals and families with a high risk of breast or ovarian cancer due to known or suspected genetic factors. Researchers collected medical records, questionnaires, and biological samples to better understand the disease's natural history and …

This study looks at whether the mobility of a cesarean scar is related to the severity of menstrual pain in women who have had a C-section. Researchers will measure scar mobility, pain levels, and pressure sensitivity in 34 women aged 20–35 with regular cycles and period pain. Th…

Researchers want to know whether the amount, location, and behavior of body fat contribute to two hormone conditions in women: hypothalamic amenorrhea, where menstrual periods stop, and polycystic ovary syndrome (PCOS). The study enrolls 50 women across five groups, including ath…

Researchers at a large hospital in Seoul reviewed records from nearly 33,000 adults who had curative-intent surgery for one of seven cancers in the abdomen or pelvis: pancreatic, gastric, rectal, cervical, endometrial, kidney, or prostate. They grouped patients by whether they re…

This phase 3 trial compares a less invasive sentinel node biopsy approach to standard staging methods in 262 women with early-stage endometrial cancer at intermediate or high risk of recurrence. The goal is to see if the sentinel node policy reduces surgical complications while s…

This study followed over 46,000 women in the Netherlands who tested positive for HPV and had mild abnormal Pap results. Researchers tracked how many developed cervical cancer within five years. The goal was to see if these women could safely have fewer follow-up tests, making scr…

Researchers want to learn which molecules on cancer cells the immune system attacks when checkpoint inhibitor drugs work well. They collect tumor and blood samples from adults with solid tumors who respond to these drugs, either during treatment or after surgery. The team then se…

Researchers at the University of California, San Francisco are running a long-term study to see whether children conceived through infertility treatment have different metabolic profiles than other children. The study has two parts: one looks back at children already born, and th…

This trial tests whether an AI-supported chatbot can boost nursing students' knowledge of gynecologic cancers and their clinical decision-making skills. Third-year nursing students who have completed their obstetrics and gynecology course will be randomly assigned to either use t…

This pilot study tests a streamlined ovarian stimulation protocol for women undergoing fertility treatment. Participants receive a single injection of corifollitropin alfa plus daily oral clomiphene citrate, instead of the usual multiple daily injections. Researchers will measure…

This study asks whether measuring circulating endothelial cells (CECs), cells shed from blood vessel walls, can predict how well ovarian cancer patients respond to standard chemotherapy with or without bevacizumab. Researchers will use a standardized flow cytometry method to coun…

This study looked at people with low or no GnRH, a hormone that controls puberty and fertility. Researchers studied 111 adults and teens to understand how GnRH problems affect the body. The goal was to find new hormone patterns and genetic causes, not to test a treatment.

This study looked at 492 women after menopause to see how often signs of endometriosis show up on routine ultrasound exams. Researchers used a standard method to check for deep endometriosis and cysts. The goal was to learn more about this condition in older women, which is not w…

Researchers at Deraya University are studying whether premenstrual syndrome (PMS) affects a woman's ability to keep balance while doing two things at once, like standing and spelling. They plan to compare 40 women aged 18 to 27 during their PMS phase and their non-PMS phase, usin…

Endometriosis causes severe pelvic pain, and many people still hurt even after treatment. Researchers suspect the nervous system amplifies pain signals, a process called central sensitization. This study tests whether six patient questionnaires can reliably measure central sensit…

This study looks at proteins in the blood of women with ovarian, peritoneal, or fallopian tube cancer who are in remission. The goal is to find a protein pattern, or 'fingerprint,' that signals when the cancer might come back. Researchers followed 119 women with stage III or IV c…

This study looks at why babies born with restricted growth (IUGR) have a higher risk of childhood obesity. Researchers will track 400 mother-infant pairs for two years, analyzing T-cell changes and DNA methylation. The goal is to uncover early biological signs that could lead to …

This study used advanced brain imaging (MRI and MEG) to look for differences in brain structure, chemistry, and activity between people with schizophrenia and healthy volunteers. Over 3,200 adults took part. The goal was to better understand the brain changes linked to schizophre…

This study looked at how diet and exercise changes affect hormones and menstrual cycles in healthy women aged 18-28. Participants followed special diets and exercise programs while researchers measured hormone levels. The goal was to better understand a condition called functiona…

This observational study will examine the molecular and epidemiological characteristics of endometrial cancer in Brazil, focusing on women diagnosed between 2016 and 2019. Researchers will analyze tumor samples for genetic mutations and biomarkers, and collect data on demographic…

This trial tests whether a 15-minute educational video and a list of suggested questions can improve understanding of immunotherapy among patients with advanced cancer and their caregivers. Participants are randomly assigned to receive the educational materials or usual care, and…

This study looked at 78 women to understand why chronic pelvic pain happens in endometriosis. Researchers examined hormones, immune chemicals, and genes, and how nerves and muscles are involved. Participants included women with endometriosis and pain, those with pain but no endom…

This pilot study is testing whether a noninvasive ultrasound device, called USCOM, can measure how well the heart is pumping blood in pregnant people who have just been diagnosed with fetal growth restriction (FGR). FGR means the baby is smaller than expected, and this condition …

This study tests whether giving gynecologic cancer patients a list of questions to ask their doctor improves their confidence, reduces distress, and builds trust. About 70 adults with newly diagnosed or suspected gynecologic cancer will either receive the question list or usual c…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…

This study investigates why some girls with Turner syndrome find it hard to make friends, read emotions, and control their feelings. Researchers will compare 35 girls with Turner syndrome to 35 girls with isolated growth hormone deficiency, all aged 7 to 16. Through puzzles, memo…

This study looks at how often women develop intrauterine adhesions (scar tissue inside the uterus) after having fibroids removed through laparoscopic or open surgery. Researchers will check for adhesions using a small camera inserted into the uterus three months after surgery. Th…

This study tests whether a family-centered developmental care program, called NIDCAP, can improve brain and behavior outcomes in preterm infants born with severe intrauterine growth restriction. The intervention involves weekly observations of each infant's behavior, with persona…

This study examines whether placentas from pregnancies with intrauterine growth restriction (IUGR) have different levels of certain progesterone receptors compared to healthy pregnancies. Researchers will analyze placental tissue collected after delivery from 90 women. The goal i…

This study investigates whether lymph nodes in the lower abdomen, called the inferior epigastric lymph node basin, might be an early stop for ovarian cancer spreading from the peritoneum. Researchers will biopsy these nodes in 20 patients undergoing surgery for ovarian peritoneal…

This study looks at women who have had one cesarean section and are now deciding how to give birth again: trying a vaginal delivery (TOLAC) or scheduling another C-section (ERCD). The goal is to compare the safety of both options for the baby and the mother. Researchers will foll…

Women who become pregnant after weight-loss (bariatric) surgery have a higher chance of delivering smaller-than-expected babies. This study tests whether tracking blood sugar fluctuations with a continuous glucose monitor during each trimester can help predict which babies will b…

This trial investigates whether women with endometriosis have different blood pressure, pain, and platelet responses compared to healthy women. Participants take aspirin or a placebo and undergo handgrip exercise, cold pressor tests, and blood draws. The goal is to understand how…

This study looks at whether a woman's expectations before endometriosis surgery influence her pain, disability, and well-being afterward. Researchers follow about 300 women for a year, tracking their symptoms and psychological factors. The goal is to understand why some women sti…

This study looks at what factors increase the risk of a serious complication called anastomotic leakage after ovarian cancer surgery. Researchers will analyze data from 401 patients to build a prediction model. The goal is to help surgeons identify high-risk patients early and ta…

This study tests whether a structured face-to-face education program can improve women's knowledge about cervical cancer and their attitudes toward the HPV vaccine. One hundred women aged 18-49 in Turkey will be split into two groups: one receives the education, the other gets ro…

This study looks at two ways to examine the uterine cavity after women have had hysteroscopic surgery for conditions like polyps, fibroids, or a uterine septum. One method is a non-invasive 3D ultrasound; the other is an office hysteroscopy, which involves inserting a small camer…

This study tests a digital education program designed to help newly diagnosed women with gynecological cancer learn about egg freezing (oocyte cryopreservation). The program uses videos, images, WhatsApp, and online meetings to teach about fertility preservation options. Research…

This study looks at how lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check for different lung ultrasound patterns and see if they relate to patient outcomes like death or nee…

This study follows 67 women with cervical cancer for one year after they finish radiation therapy. Researchers want to see how their quality of life, including physical and emotional well-being, changes over time. Participants fill out questionnaires about symptoms like fatigue, …

This study looks at how proteins in the blood change in women with ovarian cancer as they go through standard treatment. Researchers collected blood samples before surgery, after surgery, and after chemotherapy to see if these protein shifts could give a fuller picture of how the…

This study looked at whether having a special consultation with a radiotherapy technician (called a manipulator) helps cancer patients feel more informed about their treatment. Researchers enrolled 308 adults with various cancers who were getting radiation therapy. They compared …

This study looks at how sleep length and quality may affect the success of in vitro fertilization (IVF) in women. Participants will wear a ring-shaped device that tracks sleep patterns before and after a frozen embryo transfer. The goal is to see if sleep parameters like total sl…

This study follows 135 women with premature ovarian failure (early menopause) to see if hormone replacement therapy improves their sexual quality of life. Participants fill out questionnaires about sexual function and well-being before starting treatment and again 6 months later.…

This study looked at how certain enzymes called matrix metalloproteinases (MMPs) and their inhibitors relate to human papillomavirus (HPV) in cervical dysplasia and cancer. Researchers collected tissue and cell samples from 216 women with different stages of cervical lesions. The…

This completed study looked at whether a simple blood test (liquid biopsy) can help track breast, ovarian, and endometrial cancers. Researchers analyzed circulating tumor cells in 150 women to see if these cells could predict the risk of cancer spreading or how well treatment wor…

This study looked at 51 women who had a stem cell transplant for acute leukemia as adults. Researchers wanted to find out how many had gynecological problems like early menopause, vaginal graft-versus-host disease, or cervical issues two years after transplant. They also checked …

This completed study looked at a new antibody called anti-SIRPα as a potential immunotherapy for liver cancer. Researchers used blood and tissue samples from 30 liver cancer patients to see how the antibody affects immune cells. The goal was to understand whether blocking the SIR…

This study looked at two ways to help breast and ovarian cancer survivors get genetic counseling: a mailed brochure or a phone call with a health coach. About 668 women took part. The goal was to see which method led more people to actually get genetic counseling or testing. The …

This study looks at whether a score called KELIM can predict how well ovarian cancer patients respond to maintenance treatment with PARP inhibitors after initial chemotherapy. Researchers will analyze data from 243 patients who took part in the PAOLA-1 trial. If KELIM proves usef…

This study looked at 294 women with deep endometriosis affecting the rectum. Researchers compared how patients felt after conservative surgery versus more radical bowel removal. The goal was to see which approach leads to fewer bowel and bladder problems and to find factors that …

This study tested whether injecting a fluorescent dye called indocyanine green (ICG) into the ureters helps surgeons see them more clearly during laparoscopic surgery for deep infiltrating endometriosis. 51 women with suspected or confirmed deep endometriosis took part. The goal …

This study looked at 40 women to see if a physical measurement called anogenital distance (AGD) and certain hormone levels differ between those with and without endometriosis. Researchers measured AGD and took blood and saliva samples before and after showing an empathy-inducing …

This study followed 40 women with cervical, uterine, or ovarian cancer to see how their relationship and sexual communication changed from diagnosis to 3 months after treatment. Participants filled out questionnaires about their sexual activity, desire, and discomfort. The goal w…

This study looked at 1,500 women with advanced ovarian, peritoneal, or fallopian tube cancer to see how genetic changes in their tumors relate to how the disease progresses. Researchers collected tumor samples and medical data to find links between DNA abnormalities and outcomes …

This study looked at a protein called osteopontin in the blood of pregnant women whose water broke too early (PPROM). Researchers compared 71 women with early rupture to those with normal-term rupture to see if protein levels differ. The goal was to learn more about the biology b…

This study looked at whether measuring the stiffness of uterine fibroids can help predict how well they respond to a non-invasive treatment called MR-HIFU. Forty women with symptomatic fibroids were enrolled. The goal was to improve patient selection so that only those likely to …

This pilot study tested a new device that measures cervical stiffness in 21 pregnant women at high risk for preterm birth. The goal was to see if stiffness measurements could improve risk assessment beyond standard ultrasound checks. Researchers hope this could lead to better pre…

This study tested whether a two-hour, peer-led workshop with religious messages could encourage Muslim women in North East England and Scotland to get screened for breast, bowel, and cervical cancer. 169 women aged 25-74 who were not up-to-date with all eligible screenings took p…

This study collected ultrasound and MRI images from 100 women with endometriosis who were scheduled for surgery. The goal was to create a database that helps doctors better identify and stage the disease using these scans. Participants were aged 18-40, had a clinical diagnosis, a…

This study looked at how doctors in Russia treat a specific type of ovarian cancer called HRD-positive. Researchers collected information from 414 patients to understand what treatments they received and how they fared. The goal was to describe real-world practice, not to test a …

This study tested a Portuguese version of the DIVA questionnaire to see if it reliably measures how vaginal aging symptoms (like dryness, itching, or pain) affect daily activities, sex life, emotions, and body image. 300 women with at least one symptom of vulvovaginal atrophy too…

This study looked at whether a special PET/CT scan, done within two months after treatment, helps doctors make better decisions for patients with advanced cervical cancer. Researchers compared what doctors would decide without the scan versus with it. The study involved 40 patien…

This study tested a digital health platform to help people with a hereditary risk of breast and ovarian cancer share their genetic test results with family members. Researchers worked with 128 participants in Switzerland and Korea to see if the tool reduced distress and improved …

This study looked back at 388 women with advanced ovarian, fallopian tube, or peritoneal cancer who were taking the drug niraparib as maintenance therapy. Researchers wanted to see how often serious side effects happened and how patients used the drug in real-life UK clinics. No …

This study looked at 30 women with PCOS who had trouble ovulating. Researchers measured a hormone called AMH while giving low doses of FSH to see if a drop in AMH happens when an egg follicle starts to grow. The goal was to better understand why ovulation fails in PCOS, not to te…

This study looked at 40 women with symptomatic uterine fibroids to understand why MR-guided focused ultrasound (HIFU) works better for some than others. Researchers used MRI and contrast-enhanced ultrasound to measure fibroid blood flow, stiffness, and other features before treat…

This study looked at whether a common vaginal yeast, Candida albicans, plays a role in endometriosis. Researchers compared 48 women with and without endometriosis to see if yeast overgrowth was more common in those with the disease. The goal was to better understand what causes e…

This study tested whether a family history app can help doctors collect and use information about patients' family health risks. Over 600 adults aged 30-69 took part. The goal was to see if the app leads to better screening and genetic referrals for conditions like cancer, heart …

This study reviewed over 11,000 patients with advanced ovarian cancer to see if hospitals that follow ten specific quality standards for surgery have better outcomes. The research looked at how long patients lived without their cancer getting worse and overall survival. The goal …

This completed study looked at how often joint pain occurs in 71 people with ovarian, colorectal, or lung cancer who were taking the drug bevacizumab. Participants filled out a questionnaire about their joint pain over 6 months. The goal was to better understand this side effect.

This study tested whether a flexible, personalized exercise program is practical for cancer patients receiving chemotherapy. Twenty-one adults with breast, ovarian, or colorectal cancer took part. The main goal was to see if patients would join, attend, and stick with the exercis…

This study tested different ways to teach physical activity-related health competence to nursing students in Bavaria. Over 300 students from 16 schools participated, with some schools using new teaching methods and others serving as controls. The goal was to see which approach be…

This study follows over 1,700 women who previously took part in a cervical cancer screening trial. Researchers want to see if testing for HPV alone is as safe and effective as combining it with a Pap smear over 10 years. Participants provide a cervical sample for both tests, and …

This study tested a decision aid for women with a less active ectopic pregnancy (a pregnancy outside the womb that is not growing quickly). 109 women and their doctors used the tool and then answered questions about how helpful and clear it was. The goal was to see if the tool he…

This study looked at 172 kidney transplant recipients who were on stable anti-rejection medication for at least 3 months. Researchers measured levels of a common, harmless virus (Torque Teno Virus) in their blood to see if it could predict serious infections or organ rejection. T…

This study used ultrasound to measure the thickness between the bladder and uterus (vesicouterin thickness) and check for a 'sliding sign' in 117 pregnant women at term. Half had at least one prior C-section, half did not. The goal was to see if ultrasound can detect adhesions th…

This study tested a tool built into electronic health records that prompts doctors to discuss heart health with cancer survivors during routine visits. Researchers enrolled 645 survivors of breast, prostate, colorectal, endometrial, and lymphoma cancers across 12 clinics. The goa…

This study looked at whether following national guidelines for ovarian cancer surgery is cost-effective. Researchers measured the cost per quality-adjusted life year (QALY) over three years in 200 women with advanced ovarian cancer. The goal was to understand the economic impact …

This completed study tested whether a new biomarker called 'mass response' can predict how well a cancer therapy will work. Researchers collected tumor cells from 72 patients with various cancers through fluid drainage or biopsies. The goal was to see if this biomarker could guid…

This study looked at whether a 4-week resistance training program is doable for women who had pregnancy complications like preeclampsia or preterm birth. Seven new moms participated, and researchers measured how well they stuck with the exercises and how they felt about them. The…

This study looked back at 46 women who had a procedure called uterine artery embolization to treat fibroids. The goal was to see how often women later had a baby and what pregnancy complications occurred. The researchers reviewed medical records from one hospital in France to gat…

This study looked at whether using frozen embryos instead of fresh ones in IVF leads to more live births. 237 women took part, and researchers compared pregnancy rates and baby health. The goal was to see if freezing embryos helps the womb lining work better.

This study looked at 22 women with cervical cancer to see if having an empty bladder (using a catheter) or a full bladder (filled with 120cc of fluid) is better during a type of internal radiation called brachytherapy. The goal was to find which method lowers the radiation dose t…

This study examined 33 preterm babies born before 30 weeks to mothers with preeclampsia. Researchers measured certain proteins in the mother's blood, umbilical cord blood, and amniotic fluid to see if they were linked to a lung condition called bronchopulmonary dysplasia (BPD). T…

This study followed 81 pregnant women whose babies were growing slowly in the womb (a condition called IUGR). Researchers used ultrasound to measure blood flow in a key fetal blood vessel every week during the third trimester. They then checked if these measurements could predict…

This study looked at 386 women with cervical, uterine, or ovarian cancer to compare standard laparoscopic surgery versus robot-assisted laparoscopic surgery. The goal was to see which approach causes fewer complications within six months after the operation. Researchers tracked s…

This study explores whether using a PET-scan at the start of brachytherapy (internal radiation) is feasible for patients with locally advanced cervical cancer. Fourteen participants who have already received chemoradiation will undergo an extra PET-scan during brachytherapy and a…

This study looked at pregnant women at high risk for placenta accreta, a serious condition where the placenta grows too deeply into the womb. Researchers wanted to find out which factors, such as how the condition is diagnosed and managed, affect the mother's health. Over 600 wom…

This study looked at over 1,800 frozen embryo transfer cycles to see if a woman's body mass index (BMI) affects whether the transfer can be done as planned and if it leads to pregnancy. Researchers compared obese and non-obese women using different hormone preparation methods. Th…

This study tested a digital chatbot (called CATALYST) to help cancer survivors learn about genetic testing for inherited cancer risk. Fifty adults who had certain cancers (like breast, ovarian, or prostate) used the chatbot or received usual care. The goal was to see if the chatb…

This study tested whether a special survivorship clinic, combined with an app for reporting symptoms, is practical for women who have finished curative treatment for early-stage breast, cervical, or endometrial cancer. Two hundred women visited the clinic at the start and end of …

This study reviewed 575 adults admitted to intensive care for a severe kidney infection called acute obstructive pyelonephritis. Researchers aimed to identify factors that lead to poor outcomes such as death or lasting kidney damage. The goal is to better understand which patient…

This study looked at how a genetic test that checks 25 genes linked to hereditary cancers is used in clinics. Over 1,500 people with a personal or family history of cancer took part. Researchers collected blood samples and had participants fill out questionnaires over five years …

This study looked at how behavioral factors, hormones, and natural body chemicals might influence tumor growth in ovarian cancer. Researchers studied 613 women with ovarian cancer to understand these connections. The goal was to gather knowledge, not to test a treatment.

This study looked at whether giving women a self-collection kit for HPV testing at their family doctor's office would encourage more women to get screened for cervical cancer. The study involved 308 women aged 30-65 who were overdue for screening. Some women were offered the usua…

This study looked at how different doses and methods of giving progesterone (vaginal, under the skin, or muscle injection) affect the structure and function of the uterine lining in women preparing for embryo transfer. 109 healthy women with regular cycles took part, and research…

This completed study looked at how often fallopian tubes are completely removed when women have surgery to remove an ovary and tube (adnexectomy). The goal was to improve the surgical technique to lower the risk of ovarian cancer. 115 women participated, and researchers checked f…

This study looked at 255 women who chose to have permanent sterilization (tubal ligation) surgery. Researchers compared three different surgical approaches to see which one led to the best recovery and highest patient satisfaction. The goal was to help doctors and patients choose…

This study tested whether using an ultrasound during surgery helps doctors decide the best way to remove endometriosis from the rectum. Ten women with deep pelvic endometriosis took part. Doctors performed an ultrasound before and after shaving off the diseased tissue to see if i…

This study analyzed 2000 women who had surgery for endometriosis to see if the lesions tend to appear more on the right or left side of the pelvis. By carefully recording the location of each lesion during surgery, researchers hope to learn more about how endometriosis develops. …

This study looked at two methods to help women who have not been screened for cervical cancer get tested. One group received a vaginal self-sampling kit in the mail, while the other was invited to visit their general practitioner. The goal was to see which approach leads more wom…

This completed study looked at how muscle energy use differs in women with ovarian or endometrial cancer who are losing weight, depending on their body mass index (BMI). Researchers took blood samples, muscle biopsies, and fat tissue from 70 women during surgery. The goal was to …

This study looked at how chemotherapy impacts the quality of life of women treated for stage II or III endometrial cancer. Researchers asked 51 patients to fill out questionnaires about their physical, emotional, and social well-being at least two years after finishing treatment.…

This study looked at 267 women with early-stage cervical cancer to compare two surgical approaches: removing all pelvic lymph nodes versus removing only the sentinel (first) lymph node. The goal was to see which method causes fewer complications within 6 months after surgery. Res…

This completed study looked at whether a blood test for a substance called ADMA can measure blood vessel health in children with growth hormone deficiency or those born small for their age. Researchers compared ADMA levels to ultrasound measurements of artery function in 23 child…

This study looked at 183 women with menstrual pain to understand why it happens and how naproxen (a common painkiller) relieves it. Using MRI scans, researchers measured uterine activity, blood flow, and oxygen levels before and after taking naproxen or a placebo. The goal is to …

This study looked at 65 women with deep infiltrating endometriosis to see if the number of nerve fibers in their lesions is linked to how much pain they feel. Researchers measured nerve density in surgically removed tissue and compared it to pain scores reported by patients. The …

This study measured certain proteins (histones and HMGB1) in the blood of 115 pregnant women to see if they could help detect placenta-related complications like pre-eclampsia. Researchers compared women with normal pregnancies, those with complications, and healthy non-pregnant …

This study looked at how women feel and think after getting a personalized estimate of their breast cancer risk. Researchers used a special computer model (BOADICEA) to give each woman a risk score based on her genes. The goal was to see if this personalized information changes h…

This early study looked at whether adding a woman's own exosomes (tiny particles from her cells) to the liquid used to grow eggs in the lab could help more eggs mature. 32 women with low ovarian reserve took part. The goal was to see if the method was safe and worked, but no embr…

This study looked at whether levels of cell free DNA (tiny DNA fragments) in blood and fluid around eggs are higher in women with endometriosis who are doing IVF. Researchers compared 114 women with and without endometriosis to see if these DNA levels relate to egg quality and pr…

This study tested whether an automated system can grow cancer cells from patient samples (blood, fluid, or tumor tissue) inside chicken eggs. Researchers aimed to see if at least half of the samples would successfully grow. The goal is to create a better, cheaper way to study can…

This study looks at how the quality of life changes over time for young women with MRKH syndrome, a condition where the uterus and upper vagina are underdeveloped. Researchers followed 25 women who took part in an earlier study, asking them to fill out questionnaires about their …

This study looked at medical records from 509 adults in Taiwan to find out how often advanced cervical, endometrial, and ovarian cancers have a specific marker called HER2 IHC 3+. Researchers also described the patients' health details to better understand who might benefit from …

This study tested over 1,000 women with endometrial cancer for DNA repair problems that can be inherited (Lynch syndrome). By analyzing tumor DNA, researchers aimed to personalize cancer treatment and identify family members who might also be at risk. The goal was to improve care…

This study looked at how the location of uterine fibroids affects blood flow in the uterine artery. Researchers used ultrasound to measure blood flow in 185 women with fibroids and compared results based on fibroid location. They found that fibroids located within the uterine mus…

This study looked back at medical records of 342 women in Europe with advanced ovarian cancer and a BRCA gene mutation. All had taken the drug olaparib (Lynparza) as their first maintenance treatment after initial chemotherapy. Researchers tracked how long patients lived without …

This completed study looked back at the medical records of 74 adolescent girls aged 12 to 21 who had bone density scans. Researchers wanted to find out which girls are most at risk for low bone density (osteopenia or osteoporosis), especially those with missed periods or other gy…

This study looked at whether ospemifene, a non-hormonal drug for vaginal dryness, also affects brain activity in postmenopausal women with sexual interest-arousal disorder. Twenty-five women took the drug or a placebo and underwent brain scans while watching sexual videos or smel…

This completed study tested whether augmented reality (AR) can help surgeons during laparoscopic surgery for uterine fibroids or adenomyosis. AR overlays images from pre-surgery scans onto the live video feed, potentially making it easier to see and remove benign tumors. Forty pa…

This completed study looked at how endometriosis might affect egg quality in 16 women undergoing fertility treatment. Researchers analyzed the fluid around the eggs and cells from the egg's support cells to find any unique patterns. The goal was to see if these patterns could pre…

This completed registry study collected real-world data on 99 patients receiving HydroPearl microspheres to block blood flow to conditions like uterine fibroids, arteriovenous malformations, hypervascular tumors, and benign prostatic hyperplasia. The procedure was done through th…

This study tested whether a special brain MRI could predict which unborn babies with poor growth (intrauterine growth restriction) will have health problems after birth. Researchers scanned 82 fetuses before 32 weeks of pregnancy and compared the results to their health at delive…

This study looked at whether surgery for vaginal prolapse can be safely done as a day procedure, allowing women to go home the same day. Thirty-eight women with advanced prolapse were treated at three hospitals in Lyon, France. The goal was to see how many could actually be manag…

This study followed 102 women with ovarian, fallopian tube, or endometrial cancer through six cycles of standard chemotherapy (carboplatin and paclitaxel). Researchers measured taste changes, muscle loss, and nutritional decline at the start, halfway, and end of treatment. The go…

This study followed over 1,400 pregnant women with endometriosis to see how the disease affects pregnancy outcomes like preterm birth. Researchers compared different types of endometriosis to understand which pose higher risks. The goal is to improve pregnancy monitoring and care…

This completed study looked at 138 women with Rokitansky syndrome, a condition where the vagina and uterus are underdeveloped. Researchers compared quality of life and sexual health in women who had surgery versus those who used vaginal dilation. The goal was to see which approac…