Family study aims to unlock secrets of hereditary breast and ovarian cancer

NCT ID NCT00040222

Completed Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 36 times

Summary

This completed study enrolled 377 individuals and families with a high risk of breast or ovarian cancer due to known or suspected genetic factors. Researchers collected medical records, questionnaires, and biological samples to better understand the disease's natural history and genetic causes. No treatment was provided, but participants received genetic counseling and referrals if needed. The goal was to create a resource for future research into cancer prevention and early detection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FAMILIAL OVARIAN CANCER are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Contacts and locations

Show contact details

Locations

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

breast neoplasm Cowden disease hereditary breast carcinoma Li-Fraumeni syndrome ovarian cancer Peutz-Jeghers syndrome Risk Reduction Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRCA1-ASSOCIATE MALIGNANCIES BRCA1-ASSOCIATE MALIGNANCIES BRCA2-ASSOCIATED MALIGNANCIES BRCA2-ASSOCIATED MALIGNANCIES FAMILIAL BREAST CANCER FAMILIAL OVARIAN CANCER