Could a Two-Drug combo speed up delivery after pregnancy loss?
NCT ID NCT05322252
First seen Apr 14, 2026 · Last updated Jun 22, 2026 · Updated 9 times
Summary
This pilot study tested whether giving two medications (mifepristone and misoprostol) at the same time helps women deliver faster after a nonviable second-trimester pregnancy, compared to misoprostol alone. Thirty women between 14 and 28 weeks pregnant who needed labor induction took part. The goal was to see if more women delivered within 12 hours with the combo, while keeping safety in mind.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PREGNANCY COMPLICATIONS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Barnes-Jewish Hospital
St Louis, Missouri, 63110, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mifepristone and misoprostol
What this could lead to
If it works, this could offer a faster, safer way to complete delivery after a nonviable second-trimester pregnancy, reducing infection risk.
What could go wrong
This is a very small pilot study (30 people) with no long-term follow-up. Results may not apply to all situations, and the simultaneous regimen might not be faster or could increase side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.