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Could a cream after surgery beat cervical precancer in HIV-Positive women?

NCT ID NCT05413811

First seen Feb 18, 2026 · Last updated May 25, 2026 · Updated 12 times

Summary

This study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is acceptable and helpful for treating cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it acceptable, and to check if it helped clear the precancerous cells. The study is complete, and results will show if this combination approach is worth pursuing further.

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Contacts and locations

Locations

  • Clinical HIV Research Unit Temba Lethu Wing Helen Joseph Hospital

    Westdene, Johannesburg, 2092, South Africa

Conditions

Explore the condition pages connected to this study.