Frozen embryo transfers may boost IVF success, study finds

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women \[18 - 40\[years of age (according to date of birth at time of informed consent) who are eligible for ovarian stimulation and ART treatment, including intracytoplasmic sperm injection (ICSI) * Absence of anatomical abnormalities of the reproductive tract that would interfere with implantation or pregnancy * Absence of any medical condition in which pregnancy is contraindicated * Motile, ejaculatory sperm must be available (donated and/or cryopreserved sperm is allowed). Intracytoplasmic sperm injection (ICSI) will be allowed during this trial * Body mass index 18 to 35 kg/m2, inclusive * Able to understand the study * Affiliation with a social security scheme * Dated and signed inform consent Exclusion Criteria: * Altered ovarian reserve (Day3: FSH \>12 UI/l; AMH\<1,0 ng/ml; AFC\<8) * History or presence of tumours of the hypothalamus or pituitary gland * Presence of non isolated uni- or bilateral hydrosalpinx * Abnormal gynaecological bleeding of undetermined origin * Contraindication to being pregnant and/or carrying a pregnancy to term * Known infection with human immunodeficiency virus, active hepatitis B or C virus in the female or male partner * History or presence of ovarian, uterine or mammary cancer * Known allergy or hypersensitivity to human gonadotropin preparations or to compounds that are structurally similar to any of the other medications administered during the trial * Substance abuse that would interfere with trial conduct, as determined by the investigator * Use of testicular or epididymal sperm * Pregnant patient, nursing patient * Participation in another ART clinical trial within the past 30 days * Women who have risk to develop severe ovarian hyperstimulation syndrome (OHSS) during controlled ovarian stimulation (COS) defined as ≥ 18 follicles measuring 10 - 14 mm on the day of triggering * Women with less than 3 follicles ≥ 15 mm on the triggering day or the day before the triggering * Women with premature progesterone elevation during COS ( ≥1.5 ng/ml) * Women with uterine polyps diagnosed during COS * Participation with another interventional study involving human subjects