Michigan study tests ways to boost genetic testing in cancer patients
NCT ID NCT05162846
First seen Jun 27, 2026 · Last updated Aug 19, 2026 · Updated 2 times
Summary
This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to see if these approaches made it more likely for people to complete testing within six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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793 people
The number who actually took part.
- Started
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Apr 2022
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Able to speak and read English * Access to the internet * Completed the Family Health History Tool (FHHT) * Meeting clinical criteria for genetic evaluation due to any of the below: 1. Personal history of Breast cancer either: * i. Diagnosed under 50 * ii. Personal or family history of triple negative breast cancer * iii. Ashkenazi Jewish ancestry * iv. Male proband * v. 1st or 2nd degree relative with ovarian cancer, pancreatic cancer, breast cancer diagnosed under 50, or male breast cancer 2. Personal history of prostate cancer either: * i. Diagnosed under 50 * ii. Ashkenazi Jewish ancestry * iii. 1st or 2nd degree relative with ovarian cancer, pancreatic cancer, breast cancer diagnosed under 50, or male breast cancer 3. Personal history of any cancer or no personal history of cancer with either: * i. PREMM score ≥ 2.5% * ii. 1st degree relative with pancreatic, or male breast cancer * iii. 1st or 2nd degree relative with ovarian cancer * iv. 1st degree relative with any of these cancers diagnosed under 50: colon, endometrial, or breast * v. Ashkenazi Jewish ancestry and 1st or 2nd degree relative with breast cancer 4. Personal history of endometrial cancer diagnosed under 50 5. Personal history of colorectal cancer diagnosed under 50 6. Personal history of renal cancer diagnosed under 46 7. Personal history of sarcoma diagnosed under 46 and a 1st or 2nd degree relative with sarcoma, breast cancer, or brain cancer diagnosed under 56 8. Personal history of brain cancer diagnosed under 46 and a 1st or 2nd degree relative with sarcoma, breast cancer, or brain cancer diagnosed under 56 9. Personal history of any two of the following cancers with at least one of them diagnosed under 46: breast, sarcoma, or brain 10. Personal history of ovarian cancer 11. Personal history of pancreatic cancer 12. Personal history of adrenal cortical carcinoma Exclusion Criteria: * Prior clinical germline genetic testing for cancer or already have an upcoming appointment scheduled with a genetics provider
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
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Other studies related to the condition(s) this trial covers.
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