PCOS puzzle: does a key hormone drop trigger ovulation?
NCT ID NCT00492882
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 30 women with PCOS who had trouble ovulating. Researchers measured a hormone called AMH while giving low doses of FSH to see if a drop in AMH happens when an egg follicle starts to grow. The goal was to better understand why ovulation fails in PCOS, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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30 people
The number who actually took part.
- Start date
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Nov 2003
- Finished
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Jan 2007
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * normal sperm analysis in the partners and normal hysterosalpingography in all patients * PCOS defined by Rotterdam criteria * resistance to clomiphene citrate, i.e. no ovulation at 150 mg/day or no pregnancy after 6 ovulatory cycles * informed consent before inclusion Exclusion Criteria: * on-going pregnancy * age\<18 or \>40 yr. * unability to understand the treatment protocol * other medications * any co-existent morbid condition contra-indicating a pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Jeanne de Flandre - C.H.R.U.
Lille, 59037, France
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Other studies related to the condition(s) this trial covers.
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