One-Patient trial tests keytruda for rare ovarian cancer
NCT ID NCT05368207
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the drug pembrolizumab (Keytruda) as a follow-up treatment for one patient with a rare type of ovarian cancer called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). The goal was to see if the drug could help keep the cancer from coming back. Because only one person took part, the results are very limited and cannot be generalized.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pembrolizumab (Keytruda), a drug that helps the immune system fight cancer
- What this could lead to
- If it works, this could point toward a treatment option for a rare and aggressive ovarian cancer.
- What could go wrong
- This is a single-patient study with no control group, so results may not apply to others. The drug may not prevent cancer from returning and can cause immune-related side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
1 person
The number who actually took part.
- Started
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Dec 2021
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) Exclusion Criteria: * N/A
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Princess Margaret Cancer Centre
Toronto, Ontario, M5G 2M9, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a pill shrink Hard-to-Treat ovarian tumors?