University Health Network, Toronto
Clinical trials sponsored by University Health Network, Toronto, explained in plain language.
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Heat, not knife: new trial aims to cure thyroid cancer in 30 minutes
⭐️ CURE ⭐️ Recruiting nowThis study tests whether a minimally invasive procedure called radiofrequency ablation (RFA) can cure small, low-risk papillary thyroid cancers. Thirty adults who decline surgery or active surveillance will receive ultrasound-guided RFA, which uses heat to destroy the tumor. Rese…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: ⭐️ CURE ⭐️
Last updated May 26, 2026 02:03 UTC
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Blood test could spot hidden cancer and stop it for good
⭐️ CURE ⭐️ Recruiting nowThis study tests whether a blood test that detects tiny bits of tumor DNA can identify lung cancer patients whose cancer might return after surgery. Those with positive results receive extra treatment (chemo plus immunotherapy) to try to eliminate any remaining cancer cells. The …
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: ⭐️ CURE ⭐️
Last updated May 26, 2026 02:00 UTC
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Can a pandemic flu shot protect vulnerable transplant patients?
⭐️ VACCINE ⭐️ Recruiting nowThis study tests a two-dose pandemic H5N1 (bird flu) vaccine in 120 organ transplant recipients. The goal is to see if the vaccine is safe and helps their immune system fight the flu. Participants must be at least 18 years old, more than 3 months post-transplant, and have stable …
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: ⭐️ VACCINE ⭐️
Last updated May 26, 2026 02:11 UTC
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Zapping prostate tumors without major side effects: new trial launches
Disease control Recruiting nowThis study tests a procedure called irreversible electroporation (IRE) using the NanoKnife system to treat intermediate-risk prostate cancer. The goal is to destroy cancer cells with fewer side effects than standard treatments like surgery or radiation. About 100 men over age 50 …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:13 UTC
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New hope for lung transplant patients: drug combo aims to knock out CMV faster
Disease control Recruiting nowThis study tests whether adding the drug letermovir to standard antiviral treatment helps clear cytomegalovirus (CMV) infection faster in people who have received a lung transplant. About 40 participants will receive either the combination or standard care plus a placebo. The goa…
Phase: PHASE4 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:12 UTC
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Lung bath chemo trial aims to wipe out hidden sarcoma cells during surgery
Disease control Recruiting nowThis early-phase study tests a technique called in vivo lung perfusion (IVLP) that delivers chemotherapy directly into the lung during surgery to remove sarcoma tumors that have spread to the lungs. The goal is to kill any microscopic cancer cells left behind, which standard surg…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:11 UTC
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New laser zaps prostate tumors without major surgery
Disease control Recruiting nowThis study tests a new, less invasive treatment for men with intermediate-risk prostate cancer. Doctors use micro-ultrasound to guide a laser that destroys the tumor, aiming to control the disease and delay or avoid the need for surgery or radiation. The study enrolls 7 men aged …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:11 UTC
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One-Week radiation may spare women from mastectomy after breast cancer returns
Disease control Recruiting nowThis study tests whether a 1-week course of focused radiation after surgery is safe and effective for women whose breast cancer has come back in the same breast after prior radiation. About 171 women with small, early-stage recurrences will receive this short treatment. The goal …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:09 UTC
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New trial aims to snuff out melanoma before it returns
Disease control Recruiting nowThis study is for people with high-risk melanoma who have had surgery to remove their cancer. It uses a blood test to find tiny bits of tumor DNA that might be left behind. Participants will receive either a standard immunotherapy or a combination of two immunotherapy drugs to se…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:09 UTC
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Can a Chemo-Radiation combo boost CAR t success in tough lymphoma?
Disease control Recruiting nowThis study is for adults with a type of blood cancer called DLBCL that has come back or not responded to treatment. It tests different combinations of chemotherapy and radiation given before standard CAR T cell therapy to see if they can make the treatment work better and be safe…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:09 UTC
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New hope for liver cancer patients after transplant failure?
Disease control Recruiting nowThis study tests a drug called cabozantinib in 20 adults whose liver cancer came back after a liver transplant. The goal is to see if the drug can control the cancer and slow its growth. Participants take the drug until it stops working or side effects become too severe.
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:08 UTC
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Could multiple myeloma treatment move out of the hospital?
Disease control Recruiting nowThis study looks at whether a cancer drug called teclistamab can be given safely in an outpatient clinic instead of the hospital for people with relapsed or refractory multiple myeloma. It involves 15 adults who have already tried at least three other treatments. The goal is to c…
Phase: PHASE4 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:07 UTC
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New Drug-Radiation combo aims to control advanced lung cancer
Disease control Recruiting nowThis early-stage study tests the safety of combining the drug talazoparib with low-dose chest radiation in people with extensive-stage small cell lung cancer. About 24 participants who have finished initial chemotherapy without their cancer getting worse will take talazoparib pil…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:07 UTC
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Robotic surgery may replace chemo for testicular cancer
Disease control Recruiting nowThis study tests a robotic surgery (R-RPLND) as the first treatment for stage IIA/B testicular seminoma, instead of chemotherapy or radiation. It involves 25 men whose cancer has spread to lymph nodes in the abdomen. The goal is to see if this minimally invasive approach can cont…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:07 UTC
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Brain zaps may steady shaky steps in rare movement disorder
Disease control Recruiting nowThis study tests whether deep brain stimulation (DBS) in the cerebellum can safely improve walking and coordination in people with ataxia that hasn't responded to other treatments. Twelve adults aged 20 to 70 with primary ataxia will receive DBS implants, and researchers will mon…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:02 UTC
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Smart radiation: targeting cancer spots, sparing healthy tissue
Disease control Recruiting nowThis study tests a new way to give radiation to men whose prostate cancer has returned after surgery. Using a special scan (PSMA PET) to find exactly where the cancer is, doctors will give higher radiation doses to those spots and lower doses to healthy areas. The goal is to bett…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:01 UTC
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New drug cocktail offers hope for rare blood cancer patients
Disease control Recruiting nowThis study tests whether combining two drugs, venetoclax and azacitidine, is safe and effective for people with advanced myeloproliferative neoplasms (MPN), a rare blood cancer. About 40 participants will receive the combination to see if it can bring the disease back to a less a…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:01 UTC
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Zapping cancer spots may buy time before stronger drugs needed
Disease control Recruiting nowThis study tests whether giving focused radiation (SBRT) to all visible cancer spots, while continuing current medication, can better control prostate cancer than switching to a stronger drug right away. It is for men with castrate-resistant prostate cancer that has spread to a f…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:01 UTC
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New radiation boost shows promise for tough pancreatic cancer
Disease control Recruiting nowThis study tests whether a high-dose radiation boost after standard chemotherapy can help people with locally advanced pancreatic cancer live longer and feel better. About 43 participants whose tumors shrank or stayed stable after chemo will receive targeted radiation. Researcher…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:01 UTC
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Chemo delivered straight to lungs during surgery: a new hope for colorectal cancer patients?
Disease control Recruiting nowThis study tests a new technique called In Vivo Lung Perfusion (IVLP) that delivers chemotherapy directly into one lung during surgery to remove lung tumors. The goal is to kill any remaining cancer cells while reducing side effects on the rest of the body. About 10 adults with c…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:01 UTC
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Can IV iron boost recovery after heart surgery?
Disease control Recruiting nowThis study tests whether giving iron through a vein (IV) after heart surgery helps people with iron-deficiency anemia recover better. About 60 adults having planned open heart surgery will receive either IV iron or a placebo. The goal is to see if this treatment helps them spend …
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 01:59 UTC
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Could a common diabetes pill slow kidney decline in dialysis patients?
Disease control Recruiting nowThis study tests whether a daily 25 mg dose of empagliflozin, a drug typically used for diabetes, is safe and can help preserve the small amount of kidney function still present in people on peritoneal dialysis. About 20 adults with end-stage kidney disease who produce at least 2…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 01:59 UTC
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Exercise program aims to protect hearts of young cancer survivors
Disease control Recruiting nowThis study tests a 6-month program of supervised exercise, heart risk management, and online support for young cancer survivors (ages 18-45) who have mild heart dysfunction after cancer treatment. The goal is to see if this program improves fitness, heart function, and quality of…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 01:58 UTC
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Could hepatitis b donor lungs save more lives? new safety trial begins
Disease control Recruiting nowThis study tests whether lungs from donors with hepatitis B can be safely transplanted into people who do not have the virus. The lungs are treated with a special machine (EVLP) and UV light to kill the virus, and recipients take antiviral drugs. The goal is to see if this approa…
Phase: PHASE4 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 01:58 UTC
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New combo therapy hopes to shrink tough lung tumors
Disease control Recruiting nowThis early-phase study tests whether adding the experimental drug binimetinib to the immunotherapy pembrolizumab can help shrink tumors in people with advanced non-small cell lung cancer. About 40 participants whose cancer has a specific marker (PD-L1 ≥50%) will receive the combi…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Smart radiation zaps spreading prostate cancer with fewer side effects
Disease control Recruiting nowThis study tests a new type of radiation for prostate cancer that has spread to lymph nodes in the abdomen or pelvis. About 26 men will receive targeted, high-dose radiation that adapts to the tumor's shape each day. The goal is to control the cancer while reducing side effects o…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Radiation zaps may buy time for melanoma patients
Disease control Recruiting nowThis study is for people with metastatic melanoma whose cancer has started growing in a few spots despite treatment. Researchers want to see if giving high-dose, precise radiation to those spots can delay further spread. About 52 adults will take part, and the main goal is to see…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Smart scans and DNA tests guide lymphoma therapy in new trial
Disease control Recruiting nowThis study tests a personalized approach for people with untreated diffuse large B-cell lymphoma (DLBCL). After initial chemotherapy, doctors use PET scans and blood DNA tests to decide if a patient can safely get less chemotherapy or needs a stronger drug called glofitamab. The …
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Anal cancer trial tailors radiation dose using MRI guidance
Disease control Recruiting nowThis study tests a new way to give radiation therapy for anal cancer using MRI guidance to adjust the dose based on each person's risk level. About 80 adults with anal cancer will receive this personalized treatment. Researchers hope to reduce cancer return and find better ways t…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New drug combo could tame autoimmune hepatitis and cut steroid use
Disease control Recruiting nowThis study tests whether adding belimumab to standard treatment can better control autoimmune hepatitis, a chronic liver disease where the immune system attacks the liver. About 48 adults with active or well-controlled disease will receive weekly belimumab injections for 72 weeks…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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New drug aims to wipe out hidden cancer cells in head and neck cancer survivors
Disease control Recruiting nowThis study tests a drug called AZD2936 in about 100 people with high-risk head and neck cancer who still have signs of cancer DNA in their blood after standard treatment. The goal is to see if the drug can clear those cancer signals and prevent the cancer from coming back. Partic…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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New hope for brain tumor patients: experimental drug targets hard-to-treat gliomas
Disease control Recruiting nowThis study tests a drug called tarlatamab in 44 adults with a specific type of brain tumor (IDH-mutant glioma) that has returned or stopped responding to treatment. The goal is to see if the drug can control the tumor and boost the immune system's attack on cancer cells. Particip…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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New drug combo could help kidney transplant patients stay healthier
Disease control Recruiting nowThis study tests whether taking two common diabetes and heart drugs together (dapagliflozin and semaglutide) is safe and helpful for people who have received a kidney transplant. About 20 adults who are at least 3 months post-transplant will take the drugs for 12 weeks. The goal …
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 18, 2026 12:08 UTC
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New hope for pancreatic cancer: targeted combo trial for BRCA/PALB2 patients
Disease control Recruiting nowThis study tests a new combination of chemotherapy drugs (NABPLAGEM) against the standard combo for people with advanced pancreatic cancer that has a BRCA1/2 or PALB2 gene mutation. The goal is to see if the new combo works better at shrinking tumors and helping people live longe…
Phase: PHASE2, PHASE3 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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High-dose lung radiation shows promise in shrinking tumors
Disease control Recruiting nowThis study is testing a type of radiation called stereotactic body radiation therapy (SBRT) for people with lung cancer or cancer that has spread to the lung. The treatment delivers high doses of radiation in just 3 to 10 sessions over 1 to 2 weeks. Researchers want to see how we…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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One-shot radiation blast aims to crush liver tumors
Disease control Recruiting nowThis study tests whether a single, extremely high dose of radiation delivered by a special MRI-guided machine (MR-Linac) can better control liver tumors that have spread from other cancers compared to the usual high dose. About 114 adults with up to three liver metastases from sp…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Could Every-Other-Day radiation be just as good for prostate cancer?
Disease control Recruiting nowThis study compares two ways of giving radiation after prostate cancer surgery. One group gets standard daily radiation for 4 weeks. The other gets stronger doses every other day for about 2 weeks. The goal is to see if the shorter schedule causes similar side effects and control…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Chilled platelets may improve bleeding control in heart surgery
Disease control Recruiting nowThis study tests whether cold-stored platelets work as well as standard room temperature-stored platelets to control bleeding in adults having heart surgery. About 150 participants will be randomly assigned to receive one type of platelet transfusion. The goal is to see if a larg…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Zapping away heart arrhythmias: radiation without surgery shows promise
Disease control Recruiting nowThis study tests a non-invasive radiation treatment for people with serious heart rhythm problems that haven't improved with medication or standard procedures. About 60 participants will receive a single, focused dose of radiation to the problem area of the heart. Researchers wil…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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New pill could help immune system fight rare sarcomas
Disease control Recruiting nowThis study tests an experimental oral drug called ABSK043 in about 20 people with advanced angiogenic sarcomas (intimal sarcoma, head/neck angiosarcoma, or EHE). The drug blocks a protein called PD-L1 to help the immune system attack cancer cells. The main goal is to see if the d…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 07, 2026 18:39 UTC
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Nanoparticle imaging agent could spot hidden tumors in women with advanced cancer
Diagnosis Recruiting nowThis early-stage trial tests a new imaging drug called porphysome nanoparticles in 24 women with advanced gynecological cancers that have spread. The goal is to see if the drug is safe and how it travels through the body to improve PET/CT scans. Participants will receive one dose…
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 26, 2026 02:02 UTC
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Needle showdown: could a new tool improve sarcoidosis diagnosis?
Diagnosis Recruiting nowThis study compares two types of needles used during a lung ultrasound procedure to collect tissue samples from swollen lymph nodes. The goal is to see which needle provides better samples for diagnosing sarcoidosis, a condition that causes inflammation. About 128 adults with sus…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 26, 2026 02:01 UTC
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New blood test and camera could spot breast cancer earlier
Diagnosis Recruiting nowThis study is testing two experimental methods—a blood test called liquid biopsy and a special camera called PEM—to see if they can help doctors find and understand breast abnormalities better in women at high risk for breast cancer. About 100 women who are already scheduled for …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 22, 2026 14:04 UTC
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New study aims to sharpen lung cancer staging for better treatment
Diagnosis Recruiting nowThis study compares a newer, less invasive technique called EBUS-TBNA with standard CT/PET scans to see which more accurately stages lymph nodes in patients with early-stage lung cancer who are scheduled for stereotactic body radiotherapy (SBRT). Accurate staging helps doctors de…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 22, 2026 14:04 UTC
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New portable PET scanner could ease Alzheimer's diagnosis bottleneck
Diagnosis Recruiting nowThis study compares a new, smaller and mobile PET scanner (Radialis PET Imager) to standard PET/CT or PET/MR scanners for imaging amyloid plaques in the brain. Amyloid plaques are a hallmark of Alzheimer's disease. The goal is to see if the new device can produce equally useful i…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 22, 2026 14:01 UTC
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Blood test could spot cancer early in High-Risk patients
Diagnosis Recruiting nowThis study is testing a new blood test that looks for tiny bits of tumor DNA to find cancer early in people with inherited cancer syndromes. About 1,000 participants will give blood samples and answer questionnaires. The goal is to see if the test can detect cancer sooner than st…
Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 19, 2026 11:48 UTC
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Green dye could replace standard method for spotting breast cancer spread
Diagnosis Recruiting nowThis study tests if a special green dye called indocyanine green (ICG) can find cancer in lymph nodes as accurately as the standard two-dye method in people with breast cancer who have already had chemotherapy. About 100 adults will receive both the new dye and the standard dyes …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated May 18, 2026 11:59 UTC
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Simple drug during surgery may stop chronic pain in breast cancer patients
Prevention Recruiting nowThis study tests whether giving the numbing drug lidocaine through a vein during breast cancer surgery can prevent persistent pain that often lasts for months after the operation. About 1,600 adults having a lumpectomy or mastectomy will be randomly assigned to receive either lid…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Prevention
Last updated May 14, 2026 12:02 UTC
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Eye training may boost vision in glaucoma patients
Symptom relief Recruiting nowThis study tests a special eye exercise program called biofeedback training for people with glaucoma, a disease that can damage eyesight. The training helps patients learn to use the healthy parts of their retina more effectively. Researchers will compare 70 participants who rece…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:13 UTC
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New study aims to settle debate on best neck pain procedure
Symptom relief Recruiting nowThis study compares two methods of using radiofrequency to treat chronic neck pain caused by arthritis in the spine joints. About 72 adults with moderate to severe neck pain will be randomly assigned to one of two needle techniques. The goal is to see which approach provides bett…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:13 UTC
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AI guides surgeons to safer gallbladder removals
Symptom relief Recruiting nowThis study tests whether an artificial intelligence tool can help surgeons perform gallbladder removal more safely. About 70 patients having laparoscopic cholecystectomy will be randomly assigned to surgery with or without AI guidance. The goal is to see if AI helps surgeons achi…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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Can surgery improve life for breast cancer that returns to the chest wall?
Symptom relief Recruiting nowThis study follows 104 breast cancer patients whose cancer has spread to the chest wall and who are having surgery to remove the affected area. The goal is to see how the surgery impacts their quality of life, pain, and survival. Researchers hope to provide better evidence for tr…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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New screening system could make palliative care more efficient for cancer patients
Symptom relief Recruiting nowThis study tests a new approach called STEP2, which uses online symptom screening to decide which advanced cancer patients need a palliative care referral. It compares this targeted method to giving everyone a routine referral. The goal is to see if STEP2 works just as well at im…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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New lattice radiation aims to crush tumor pain better than standard therapy
Symptom relief Recruiting nowThis study compares a new type of radiation called Lattice therapy to standard radiation for people with large solid tumors (at least 5 cm) that cannot be removed by surgery. The goal is to see if Lattice therapy provides better pain relief 30 days after treatment. About 148 adul…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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Spinal zaps and muscle pulses: new combo therapy aims to steady MS patients
Symptom relief Recruiting nowThis study tests whether adding two types of electrical stimulation to balance training can improve mobility and reduce fall risk in people with Multiple Sclerosis (MS). Up to 24 participants will be randomly assigned to balance training alone, with muscle stimulation (FES), or w…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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Shorter radiation course may ease side effects for men with advanced prostate cancer
Symptom relief Recruiting nowThis study is for men with prostate cancer that has spread to other parts of the body. It compares two ways of giving radiation to the prostate: one schedule gives treatment every other day for two weeks, the other once a week for six weeks. The goal is to see if the shorter sche…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:12 UTC
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New therapy aims to ease trauma for parents of kids with cancer
Symptom relief Recruiting nowThis study tests a therapy called EASE for parents whose child has cancer. It aims to reduce traumatic stress symptoms over six months. About 306 parents will either get EASE plus their usual support or usual support alone. They will fill out questionnaires at several points to t…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:09 UTC
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Could a Therapy-Ketamine combo stop suicidal thoughts in days?
Symptom relief Recruiting nowThis study tests whether adding ketamine to an online therapy program can quickly reduce suicidal thoughts in people with depression that hasn't improved with other treatments. About 110 adults will receive weekly online therapy for 13 weeks, and half will also get six ketamine i…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:09 UTC
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Can cannabis capsules ease arthritis pain? new study aims to find out.
Symptom relief Recruiting nowThis study tests whether daily oral cannabis extracts (CBD or THC) can reduce pain interference in 100 adults aged 40-80 with hip or knee osteoarthritis. Participants take a capsule daily for 8 weeks and track their symptoms remotely. The goal is to see if a larger trial is feasi…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:09 UTC
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Shocking new hope for stroke fall risk?
Symptom relief Recruiting nowThis pilot study tests whether combining balance training with a mild electrical stimulation to the spinal cord can improve balance and reduce falls in people who had a stroke over a year ago. Sixteen participants will be randomly assigned to receive either real or sham stimulati…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:08 UTC
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Could a simple breathing device clear long COVID brain fog?
Symptom relief Recruiting nowThis study tests a device called Hi-OxSR that lets people briefly rebreathe their own carbon dioxide. Early results suggest it may reduce brain fog and fatigue in people with Long COVID. The trial will enroll 120 adults to find the best dose and check safety.
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:08 UTC
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Can a single ketamine infusion ease daily headaches for months?
Symptom relief Recruiting nowThis study tests whether a single high-dose intravenous ketamine infusion can reduce the number and severity of headache days in people with chronic daily headaches (15+ headache days per month). 56 adults aged 18-75 will receive either ketamine or a placebo (saline) and be follo…
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:07 UTC
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Virtual rehab helps cancer survivors get back on their feet
Symptom relief Recruiting nowThis study tests an 8-week virtual rehab program (CaRE@Home) for cancer survivors who have finished treatment. It aims to reduce disability and improve physical function, anxiety, and quality of life. About 388 adults with breast, colorectal, head and neck cancer, or lymphoma wil…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:02 UTC
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New app connects young cancer survivors for support after treatment
Symptom relief Recruiting nowThis study tests whether a smartphone app that connects young adults (ages 18-40) with trained peer navigators can help them feel more in control of their health after finishing cancer treatment. About 138 people who had breast cancer, testicular cancer, lymphoma, or sarcoma will…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:02 UTC
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Breathing workouts before lung transplant may speed ICU recovery
Symptom relief Recruiting nowThis study tests whether doing special breathing exercises (inspiratory muscle training) before a lung transplant can help patients recover more quickly after surgery. About 90 adults with lung disease who are waiting for a transplant will either do these exercises or receive usu…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 02:01 UTC
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New radiation method aims to save cancer Patients' saliva
Symptom relief Recruiting nowThis study compares standard radiation therapy with a newer, daily adaptive technique to see if it can better protect the saliva glands in people with head and neck cancer. About 50 participants will be randomly assigned to one of the two treatments. The goal is to reduce dry mou…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 26, 2026 01:59 UTC
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Can early palliative care boost quality of life for blood cancer patients?
Symptom relief Recruiting nowThis study looks at whether adding early palliative care to usual treatment helps people with multiple myeloma or aggressive B-cell lymphoma feel better. About 144 patients and their caregivers will either get early palliative care plus standard care or standard care alone. Resea…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 14:05 UTC
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Wrist surgery pain breakthrough? new study tests cheap drug
Symptom relief Recruiting nowThis study tests if putting tranexamic acid (TXA) directly into the surgical wound during wrist fracture repair can lower pain and the need for strong painkillers afterward. About 90 adults having wrist surgery will be randomly assigned to receive either TXA or a placebo. The mai…
Phase: PHASE4 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Video calls ease cancer patients' fears before radiation treatment
Symptom relief Recruiting nowThis study looks at whether a video call with a radiation therapist before starting radiotherapy helps breast cancer patients feel less worried and anxious compared to a standard phone call. About 130 people will take part and fill out questionnaires at three points: when they jo…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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New radiation technique aims to ease urinary side effects for prostate cancer patients
Symptom relief Recruiting nowThis study tests if a newer, adaptive form of radiation therapy (SBRT) can reduce urinary side effects compared to standard image-guided radiation for men with localized prostate cancer. About 320 participants will be randomly assigned to one of the two radiation approaches. The …
Phase: PHASE3 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Medical cannabis under the microscope: can it ease pain, anxiety, and more?
Symptom relief Recruiting nowThis study is tracking 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep problems, anxiety, depression, or epilepsy. Researchers will use standard questionnaires to measure changes in symptoms over 24 weeks. The goal is to see how well medical cann…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Nerve block offers hope for debilitating headache sufferers
Symptom relief Recruiting nowThis study looks at whether a simple nerve block in the back of the head can temporarily relieve severe headaches caused by spinal fluid leaks. About 34 adults with this condition will receive the injection and be monitored for pain changes. The goal is to provide a safe, accessi…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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New program aims to wean surgery patients off opioids safely
Symptom relief Recruiting nowThis study tests a program for adults who take opioids for chronic pain before surgery. The program includes pain education, therapy, and a mobile app to help patients reduce opioid use and manage pain better after surgery. Researchers will compare how many patients successfully …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Can pressurized oxygen clear long COVID brain fog?
Symptom relief Recruiting nowThis study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can ease lingering COVID-19 symptoms like brain fog and fatigue. About 120 adults with long COVID will receive the treatment, and researchers will track changes in thinking speed a…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Hand surgery study aims to cut unused opioid pills
Symptom relief Recruiting nowThis study tests whether giving a standard, evidence-based opioid prescription after hand or forearm surgery leads to fewer unused pills while still controlling pain well. About 292 adults having day surgery at Toronto Western Hospital will take part. The goal is to find a balanc…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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New program aims to ease 'brain fog' for cancer patients with brain tumors
Symptom relief Recruiting nowThis study is testing a new program called the Cognitive Stepped Care Program (CSCP) for adults with brain metastases. The program screens for thinking and memory problems and offers different levels of support, from education to one-on-one coaching. Researchers want to see if th…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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New online clinic aims to restore intimacy after prostate cancer
Symptom relief Recruiting nowThis study tests a nationwide virtual clinic called SHAReClinic that provides education and counselling to help prostate cancer patients and their partners manage sexual health after treatment. About 575 people will take part, using online modules and surveys to track changes in …
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Talking therapy trial aims to ease emotional toll of ovarian cancer
Symptom relief Recruiting nowThis study tests a short counseling program called CALM for women with advanced ovarian cancer. The goal is to see if it's practical and helpful for reducing stress and improving well-being. Participants will fill out questionnaires and may receive up to 6 therapy sessions.
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Lullaby therapy: a new tune for epilepsy in pregnancy?
Symptom relief Recruiting nowThis study tests whether creating a personalized lullaby can improve quality of life and reduce stress, anxiety, and depression in pregnant women with epilepsy. Thirty first-time mothers-to-be will be randomly assigned to either take part in the Lullaby Project or receive standar…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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Could a shot of your own cells fix a creaky knee?
Symptom relief Recruiting nowThis study tests whether injections made from a person's own bone marrow or fat cells can reduce knee pain from osteoarthritis better than a placebo. About 148 adults with moderate knee arthritis will receive one of these cell injections or a dummy shot. Researchers will track pa…
Phase: PHASE2, PHASE3 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 08, 2026 12:02 UTC
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New imaging study aims to sharpen radiation for stomach and esophageal cancers
Knowledge-focused Recruiting nowThis study explores whether combining PET and MRI scans can help doctors better plan radiation therapy for people with esophagogastric cancer. Up to 15 participants will receive scans before, during, and after treatment, but the images won't change their current care. The goal is…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:13 UTC
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New scan method could spot radiation heart damage early
Knowledge-focused Recruiting nowThis study looks at 40 adults getting chest radiation for cancer. Researchers will use PET/MR scans and blood tests before and after treatment to find early signs of heart and lung problems, like pulmonary hypertension. The goal is to better predict who might develop these side e…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:13 UTC
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New study aims to unlock secrets of radiation therapy in head and neck cancer
Knowledge-focused Recruiting nowThis study is for people newly diagnosed with head and neck cancer who are getting treatment with the goal of a cure. Researchers want to see how radiation therapy changes MRI scans and immune system markers in the tumor. About 40 participants will have extra MRI scans and biopsi…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:12 UTC
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New study aims to predict sarcoma spread using scans and blood
Knowledge-focused Recruiting nowThis study is for people with aggressive soft-tissue sarcoma (grade 2 or 3, larger than 5 cm). Researchers want to see if special MRI scans and blood tests can predict whether the cancer will spread to other parts of the body. The goal is to find better ways to personalize treatm…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:12 UTC
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Lung fluid clues may predict sarcoma spread
Knowledge-focused Recruiting nowThis study collects lung fluid and tissue samples from 70 people with soft-tissue sarcoma who are already having lung surgery. Researchers will look for specific inflammatory markers (NETs) in the fluid to see if they can predict how far the cancer has spread. The goal is to bett…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:12 UTC
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AR and zaps: can a high-tech combo restore hand function after spinal injury?
Knowledge-focused Recruiting nowThis pilot study tests whether a device that combines augmented reality (AR) with functional electrical stimulation (FES) is safe and easy to use for people with cervical spinal cord injury. Seven participants will complete 20 one-hour sessions over 10 weeks, using the system to …
Phase: EARLY_PHASE1 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:10 UTC
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New imaging study could change how we track advanced prostate cancer
Knowledge-focused Recruiting nowThis study is for men with advanced prostate cancer. It uses two different PET scans (PSMA and FDG) to get a clearer picture of the cancer's biology at different stages and during treatment. The goal is to learn how these scans might help doctors choose better treatments and moni…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:06 UTC
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Blood tests could help predict Dementia's path
Knowledge-focused Recruiting nowThis study aims to create a model that better predicts how different types of dementia will progress over time. Researchers will follow 500 people with early dementia or mild cognitive impairment, using blood tests and thinking assessments. The goal is to improve prognostic confi…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:03 UTC
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Operating rooms go green: waste audit aims to cut trash and boost recycling
Knowledge-focused Recruiting nowThis study looks at how much waste is created during surgeries at Toronto Western Hospital, focusing on anesthesia-related trash. Researchers will sort through waste bins to measure what can be recycled, reused, or is thrown away incorrectly. They will also test if teaching staff…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:02 UTC
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Blood samples collected to unlock cancer secrets
Knowledge-focused Recruiting nowThis study aims to collect blood samples (liquid biopsies) from 2,500 people with cancer or at high risk for cancer. The samples will be stored and used in future research to better understand how cancers grow and respond to treatment. No new treatments are being tested; the goal…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:02 UTC
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Tailor-Made cancer trials aim to match tumors with targeted drugs
Knowledge-focused Recruiting nowThis study is for 400 people with advanced or rare cancers who have not responded to standard treatments. Doctors use each person's tumor gene profile to pick a personalized therapy. The goal is to see if this approach improves tumor shrinkage and helps more patients get targeted…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:02 UTC
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7,000-Person cancer hunt: can DNA detect hidden disease before it returns?
Knowledge-focused Recruiting nowThis study is collecting blood, tissue, urine, and saliva from 7,000 people with many types of cancer to look for tiny bits of cancer DNA left after treatment. The goal is to find out if this DNA test can spot remaining cancer early and help doctors decide on next treatments. Par…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:01 UTC
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New study probes hidden clues in head and neck tumors
Knowledge-focused Recruiting nowThis study aims to understand how head and neck tumors change during treatment by analyzing MRI scans and tissue samples. About 60 adults with newly diagnosed head and neck cancer who are scheduled for curative therapy will take part. Researchers will look for biological markers …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:01 UTC
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Global study aims to uncover hidden dangers of breathing tube removal
Knowledge-focused Recruiting nowThis study observes 3000 adult patients to learn how often complications like low oxygen or cardiac arrest happen within an hour after a breathing tube is removed. Researchers will track practices in operating rooms and intensive care units worldwide to identify risk factors and …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:01 UTC
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Ontario doctors launch registry to solve mystery of rare bone breaks
Knowledge-focused Recruiting nowThis study aims to collect detailed information from 300 people in Ontario who have had a rare type of thigh bone fracture called an atypical femur fracture (AFF). Researchers want to learn what causes these fractures and identify risk factors, especially in people taking long-te…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:01 UTC
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Smart shirt trial aims to catch radiation side effects early
Knowledge-focused Recruiting nowThis study looks at whether a special shirt called Hexoskin can help track side effects in 100 people getting radiation for cancer that has spread. Participants wear the shirt and use a phone app to report symptoms. The goal is to see if this approach is practical and can catch p…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:00 UTC
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Spine cancer study: which radiation works better?
Knowledge-focused Recruiting nowThis study watches how doctors decide between two types of radiation for people with cancer that has spread to the spine. It will compare standard radiation with a more precise type called SBRT to see which one controls pain and tumor growth better. About 100 adults with painful …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:00 UTC
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Scientists hunt for clues in ovarian cancer samples to personalize treatment
Knowledge-focused Recruiting nowThis study collects blood, tumor tissue, and other fluids from 510 people with advanced ovarian cancer. Researchers will analyze these samples to find genetic and immune markers that may predict how long patients live or how well they respond to treatment. Results may be shared w…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Brain scans aim to unlock secrets of spinal cord stimulation for chronic pain
Knowledge-focused Recruiting nowThis study looks at how spinal cord stimulation (SCS) helps people with long-term nerve pain in the back or legs. Researchers will use brain scans to understand why some types of SCS work better than others. The goal is to find out which patients are most likely to benefit and im…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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BeeHive trial seeks clues to outsmart head and neck cancer
Knowledge-focused Recruiting nowThis study is for people with head and neck cancer that has come back or spread. It tests a new drug, alone or with another drug, to see how the cancer responds. The main goal is to find biological markers in tumors and blood that predict whether the treatment works or stops work…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Pregnancy and epilepsy: are guidelines being followed?
Knowledge-focused Recruiting nowThis study looks at how well doctors follow recommended epilepsy management guidelines for pregnant women with epilepsy. Researchers will track pregnancy, delivery, and baby outcomes, as well as the mother's seizure control. About 80 participants will be observed to see if follow…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Heart scans could predict danger in fabry patients
Knowledge-focused Recruiting nowThis study looks at whether special MRI scans can spot early signs of heart damage in people with Fabry disease. Researchers will follow 300 adults with Fabry disease over time to see if these scans help predict serious heart problems like dangerous heart rhythms, heart failure, …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Massive canadian study hunts rare cancer mutations for better treatments
Knowledge-focused Recruiting nowThis study follows 5,500 Canadian cancer patients whose tumors have rare genetic changes. Researchers will collect data on how these cancers behave and how well different treatments work, including newer targeted drugs. The goal is to learn more about these uncommon mutations to …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Can a simple blood test predict cancer risk from targeted radiation?
Knowledge-focused Recruiting nowThis study looks at people with neuroendocrine tumors (NETs) who are getting or have gotten peptide radionuclide therapy (PRRT). The goal is to find early warning signs in the blood that might show who is at higher risk of developing blood cancers like myelodysplastic syndrome (M…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Gene hunt: 1,000 women join quest to decode gynecologic cancers
Knowledge-focused Recruiting nowThis study aims to learn more about gene and protein changes in gynecologic cancers (ovarian, uterine, cervical, and others). Researchers will collect tissue and blood samples from 1,000 participants before surgery or radiation. By analyzing these samples, they hope to better und…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Mice with human tumors could unlock personalized cancer treatments
Knowledge-focused Recruiting nowThis study takes tumor samples from people with breast, colorectal, or ovarian cancer and grows them in mice. Researchers then test different drugs on these mouse tumors to see which ones might work best for each person. The goal is to find personalized treatment options and lear…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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Can a blood test spot hidden cervical cancer? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether a special PET scan and a blood test for HPV can find leftover cancer cells in people with cervical cancer after they finish standard chemoradiation. About 64 adults with stage IB-IVA cervical cancer will take part. The goal is to see how well these tes…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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New MRI study aims to personalize head and neck cancer treatment
Knowledge-focused Recruiting nowThis study uses repeated MRI scans during radiation therapy to see how head and neck tumors change. Researchers hope to learn which tumor areas need higher radiation doses. About 173 people with newly diagnosed head and neck cancer will participate, along with 20 healthy voluntee…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Can a scan predict radiation success? new study aims to find out
Knowledge-focused Recruiting nowThis study looks at whether CT and MRI scans can help predict how well brain tumors will respond to radiation treatment. Researchers will scan 90 adults with brain metastases before and after radiotherapy. The goal is to validate imaging biomarkers that could guide personalized t…
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC
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Massive ICU trial aims to find best treatments for lung failure
Knowledge-focused Recruiting nowThis large, ongoing study tests several treatments for patients with severe breathing failure (acute hypoxemic respiratory failure). It includes up to 6,250 adults in the ICU who need oxygen or a breathing machine. The goal is to find which treatments—like different ventilator se…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC
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New ventilator strategy aims to reduce sedation risks
Knowledge-focused Recruiting nowThis early-stage trial tests whether a new method of giving muscle relaxants can help patients on breathing machines breathe on their own more safely. It involves 23 adults with severe breathing failure. The goal is to see if the approach is safe and feasible, not to cure or trea…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 11:59 UTC
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Can MRI make radiation smarter for liver and pancreatic cancer?
Knowledge-focused Recruiting nowThis study looks at whether using MRI scans before each radiation treatment is practical and can help doctors adjust the radiation plan for better accuracy. About 30 adults with liver or pancreatic cancer will get up to 5 extra MRIs during their radiation course. The main goal is…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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New imaging tech aims to sharpen radiation for kids with cancer
Knowledge-focused Recruiting nowThis study is testing whether a new type of imaging (HyperSight CBCT) and adaptive planning (Ethos) can better track changes in tumors and nearby organs during radiation therapy for children with non-brain cancers. Twenty children aged 18 or under will receive standard radiation …
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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Lung cancer gene test could personalize treatment
Knowledge-focused Recruiting nowThis study looks at whether tissue samples taken during a routine lung biopsy (called EBUS-TBNA) can be used to analyze gene changes in lung cancer. The goal is to see if these gene changes can help predict which treatments—like surgery, chemo, or radiation—will work best for eac…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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Could sound waves tame troubled brains? new study aims to find out
Knowledge-focused Recruiting nowThis study is testing whether low-intensity focused ultrasound (LIFUS) can safely change brain activity in people with conditions like Parkinson's disease, essential tremor, epilepsy, or substance abuse disorder. Researchers will measure brain responses and any changes in movemen…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC