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Breathing workouts before lung transplant may speed recovery

NCT ID NCT06370832

Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether doing special breathing exercises (inspiratory muscle training) before a lung transplant can help people recover more quickly after surgery. Researchers will enroll 90 adults with lung disease who are waiting for a transplant. The goal is to see if these exercises strengthen breathing muscles, reduce time on a ventilator, and improve quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult participants (≥ 18 years of age) * Lung Transplant Candidates * Participating in outpatient pulmonary rehabilitation (standard of care) * Diagnosis of Interstitial Lung Disease or Chronic Obstructive Pulmonary Disease Exclusion Criteria: * Respiratory exacerbation within the last 1 month * Neurologic or musculoskeletal conditions that may interfere with IMT or functional assessments (i.e. history of stroke, severe arthritis of hands) * Insufficient English fluency to provide informed consent or to follow study protocols * Any evidence of pneumothorax on recent imaging (\< 6 months) * Present ruptures of eardrums or infections leading to fluid behind ear drum * Marked left or right ventricular end-diastolic volume and pressure overload on right heart catheterization or echocardiogram * Severe osteoporosis with history of rib fractures * Cardiac pacemaker or other electronic or magnetic body implant * Individuals listed as rapidly deteriorating or inpatient at the time of eligibility assessment * Individuals awaiting a re-transplant * Inability of the patient to connect to the internet

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inspiratory muscle training

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre hospitalier de l'Université de Montréal (CHUM)

    RECRUITING

    Montreal, Quebec, Canada

  • Edmonton Lung Transplant Program

    RECRUITING

    Edmonton, Alberta, T6G 2G3, Canada

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • Vancouver General Hospital

    RECRUITING

    Vancouver, British Columbia, Canada

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