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When to operate? ovarian cancer trial tests best time for surgery after chemo

NCT ID NCT03579394

First seen Jan 07, 2026 · Last updated Jun 20, 2026 · Updated 23 times

Summary

This trial studied 211 women with advanced ovarian cancer who were not candidates for upfront surgery. Researchers compared having surgery after 3 rounds of chemotherapy versus after 6 rounds. The goal was to see which timing leads to longer disease-free survival. All patients received standard carboplatin and paclitaxel chemo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Grenoble-Alpes - Site Nord (La Tronche)

    Grenoble, 38043, France

  • CHU de BREST - Hôpital Cavale Blanche

    Brest, 29200, France

  • CHU de Limoges - Hôpital de la Mère et de l'Enfant

    Limoges, 87000, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre François Baclesse

    Caen, 14000, France

  • Centre Georges François Leclerc

    Dijon, 21079, France

  • Centre Hospitalier Universitaire Bretonneau

    Tours, 37000, France

  • Centre Hospitalier Universitaire Caen

    Caen, 14033, France

  • Centre Jean Bernard - Clinique Victor Hugo

    Le Mans, 72000, France

  • Centre Jean Perrin

    Clermont-Ferrand, 63000, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Clinique Médico-chirurgicale CHARCOT

    Sainte-Foy-lès-Lyon, 69110, France

  • Groupe Hospitalier Pitié Salpétrière

    Paris, 75651, France

  • Gustave Roussy

    Villejuif, 94805, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Européen Georges Pompidou

    Paris, 75015, France

  • Hôpital Privé du Confluent

    Nantes, 44202, France

  • Hôpital René Huguenin, Institut Curie

    Saint-Cloud, 92210, France

  • Hôpital Saint-Joseph

    Marseille, 13008, France

  • Hôpital Simone Veil

    Eaubonne, 95602, France

  • Hôpital de la Milétrie - Centre Hospitalier Universitaire de Poitiers

    Poitiers, 86021, France

  • Hôpital du Scorff

    Lorient, 56100, France

  • ICA - Polyclinique Urbain V

    Avignon, 84000, France

  • ICM Val d'Aurelle

    Montpellier, 34298, France

  • ICO Centre René Gauducheau

    Saint-Herblain, 44805, France

  • Institut Bergonié

    Bordeau, 33076, France

  • Institut Claudius Regaud

    Toulouse, 31059, France

  • Institut Jean Godinot

    Reims, 51056, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Carboplatin and paclitaxel chemotherapy followed by interval debulking surgery

What this could lead to

If successful, this could help doctors decide the best timing for surgery after chemotherapy to improve how long patients stay free of ovarian cancer.

What could go wrong

This is a completed trial, but it only looked at timing of surgery, not a new drug. Results may not apply to all ovarian cancer types or stages.

Conditions

The condition(s) this trial relates to.

ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.