New study tests faster abortion method for women with scarred uterus
NCT ID NCT07465016
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two approaches for inducing abortion in the second trimester for women who have a scarred uterus (e.g., from a previous C-section). One group received a laminaria tent (a seaweed rod that gently opens the cervix) for 12 hours followed by misoprostol pills, while the other group received misoprostol alone. The main goal was to see which method led to a shorter time from start to completion of abortion. The trial included 60 women aged 18-45 with a pregnancy between 13-26 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Misoprostol and Laminaria japonicum
- What this could lead to
- If successful, this could show that using a laminaria tent before misoprostol shortens the time needed for abortion in women with a scarred uterus.
- What could go wrong
- This is a small, completed Phase 4 trial with only 60 participants, so results may not apply to all women. Risks include bleeding, uterine rupture, or need for surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
60 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jan 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age range 18-45 years old. * Women with previous scarred uterus. * Presence of an indication for induction of abortion. * Estimated gestational age between 13-26 weeks as calculated from last normal menstrual period (LMP) and confirmed by abdominal ultrasound. Exclusion Criteria: * Primigravida women. * Pregnant women with placenta previa accreta spectrum. * Women with diagnosed cervical cancer. * History of cervical surgery or presence of cervical scarring. * Presence of allergy to any of the used drugs in the study. * Women withdraws or declines to participate in this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams Maternity Hospital
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.